Orofacial Cleft Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1833538
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Genes

35 genes associated with the disease Orofacial Cleft in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ARHGAP29 Rho GTPase activating protein 29
BCL3 B-cell CLL/lymphoma 3
BDNF brain-derived neurotrophic factor
BMP4 bone morphogenetic protein 4
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CBS cystathionine-beta-synthase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
DLX4 distal-less homeobox 4
EDN1 endothelin 1
EDNRB endothelin receptor type B
EYA1 EYA transcriptional coactivator and phosphatase 1
FOXE1 forkhead box E1
GREM1 gremlin 1, DAN family BMP antagonist
GRHL3 grainyhead-like 3 (Drosophila)
IRF6 interferon regulatory factor 6
JAG2 jagged 2
MSX1 msh homeobox 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYH9 myosin, heavy chain 9, non-muscle
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NECTIN1 nectin cell adhesion molecule 1
NECTIN2 nectin cell adhesion molecule 2
PNRC1 proline-rich nuclear receptor coactivator 1
PRL prolactin
PVR poliovirus receptor
SUMO1 small ubiquitin-like modifier 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFA transforming growth factor, alpha
TP63 tumor protein p63
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBR1 ubiquitin protein ligase E3 component n-recognin 1
VAX1 ventral anterior homeobox 1