| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Osimertinib (mesylate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Osimertinib (mesylate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.0993869 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0899332 |
| RAD51B | RAD51 paralog B | 0.0863013 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0850289 |
| TOX | thymocyte selection-associated high mobility group box | 0.0840859 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0831172 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0655486 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0591587 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0515206 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0503942 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0488464 |
| CABIN1 | calcineurin binding protein 1 | 0.0467963 |
| ZNF638 | zinc finger protein 638 | 0.0455757 |
| VCL | vinculin | 0.0455594 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0438854 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0429042 |
| ATRN | attractin | 0.0421516 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0404093 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.039778 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.03965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0357252 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0353577 |
| NUP58 | nucleoporin 58 | 0.0346866 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0346819 |
| CENPF | centromere protein F, 350/400kDa | 0.0346813 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0322857 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0321889 |
| ZNF608 | zinc finger protein 608 | 0.0320313 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0317761 |
| PCBP2 | poly(rC) binding protein 2 | 0.0295777 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0291196 |
| CDH18 | cadherin 18, type 2 | 0.0289824 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0287777 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 0.0287095 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.028627 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0282608 |
| DST | dystonin | 0.0282391 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0281704 |
| ADAR | adenosine deaminase, RNA-specific | 0.0280844 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0279988 |
| JMJD1C | jumonji domain containing 1C | 0.0276225 |
| RPL3 | ribosomal protein L3 | 0.0274488 |
| SET | SET nuclear proto-oncogene | 0.0273168 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0269518 |
| SPAG5 | sperm associated antigen 5 | 0.0268913 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0266436 |
| PNN | pinin, desmosome associated protein | 0.025048 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0249951 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0249639 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0244296 |
| NEBL | nebulette | 0.0241286 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0238692 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0235288 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0233037 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0230937 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0229698 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0228897 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.022539 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.022504 |
| DIDO1 | death inducer-obliterator 1 | 0.0224072 |
| PTCH1 | patched 1 | 0.0221053 |
| SP3 | Sp3 transcription factor | 0.0220136 |
| NGLY1 | N-glycanase 1 | 0.0218638 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0217943 |
| ZNF292 | zinc finger protein 292 | 0.0217524 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0217154 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0215829 |
| FMNL2 | formin-like 2 | 0.0208639 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0208052 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0207141 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0204916 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0202983 |
| CEP192 | centrosomal protein 192kDa | 0.0202008 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.019934 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0199059 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0198072 |
| FLNA | filamin A, alpha | 0.0197738 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0197017 |
| INSIG2 | insulin induced gene 2 | 0.0196541 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0196209 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0195902 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0195653 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0195653 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0194495 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0193852 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.019314 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0191871 |
| SNX3 | sorting nexin 3 | 0.0191163 |
| HELZ | helicase with zinc finger | 0.0190649 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0188967 |
| CCSAP | centriole, cilia and spindle-associated protein | 0.018825 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0184644 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0184325 |
| KIF5B | kinesin family member 5B | 0.0184273 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0183496 |
| TMF1 | TATA element modulatory factor 1 | 0.0183488 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.0182691 |
| PDS5A | PDS5 cohesin associated factor A | 0.0176785 |
| CASC3 | cancer susceptibility candidate 3 | 0.0176563 |
| RPS18 | ribosomal protein S18 | 0.0176155 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.283101 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.14498 |
| ACTG1 | actin gamma 1 | -0.124075 |
| RPS6 | ribosomal protein S6 | -0.0846315 |
| PTMA | prothymosin, alpha | -0.0730441 |
| GNAS | GNAS complex locus | -0.0707083 |
| RPLP1 | ribosomal protein, large, P1 | -0.0657378 |
| TMSB10 | thymosin beta 10 | -0.0649821 |
| RPS8 | ribosomal protein S8 | -0.0627828 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0597469 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0596205 |
| RPL28 | ribosomal protein L28 | -0.0572661 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0495685 |
| RPLP0 | ribosomal protein, large, P0 | -0.048729 |
| RPL34 | ribosomal protein L34 | -0.0468842 |
| HMGB1 | high mobility group box 1 | -0.0465161 |
| RPS21 | ribosomal protein S21 | -0.0464963 |
| RPS24 | ribosomal protein S24 | -0.046467 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0460325 |
| RPS11 | ribosomal protein S11 | -0.0457754 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0453492 |
| RPS19 | ribosomal protein S19 | -0.0447254 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0428466 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0428449 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0396163 |
| RPL32 | ribosomal protein L32 | -0.0391556 |
| RPL19 | ribosomal protein L19 | -0.0383121 |
| RPL38 | ribosomal protein L38 | -0.0381128 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0377433 |
| DEK | DEK proto-oncogene | -0.0377318 |
| TENM3 | teneurin transmembrane protein 3 | -0.0372393 |
| RPL8 | ribosomal protein L8 | -0.0368961 |
| HMGA1 | high mobility group AT-hook 1 | -0.0359799 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0356638 |
| RPLP2 | ribosomal protein, large, P2 | -0.0350587 |
| RPS28 | ribosomal protein S28 | -0.0347866 |
| EGR1 | early growth response 1 | -0.0340116 |
| RPS25 | ribosomal protein S25 | -0.0337659 |
| RPL11 | ribosomal protein L11 | -0.0335636 |
| NF1 | neurofibromin 1 | -0.0334775 |
| RPS29 | ribosomal protein S29 | -0.0334412 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0326909 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0326802 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0325327 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0323586 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0322952 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0318238 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0315419 |
| RPS15 | ribosomal protein S15 | -0.0311688 |
| RPS5 | ribosomal protein S5 | -0.0306786 |
| RPS13 | ribosomal protein S13 | -0.0305554 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0304671 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0302872 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0300985 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0300561 |
| FUS | FUS RNA binding protein | -0.0297843 |
| RPL37A | ribosomal protein L37a | -0.029674 |
| CADM2 | cell adhesion molecule 2 | -0.0291293 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0289464 |
| ADNP | activity-dependent neuroprotector homeobox | -0.028313 |
| RPS27A | ribosomal protein S27a | -0.0281648 |
| RPL23 | ribosomal protein L23 | -0.0279486 |
| RPL36A | ribosomal protein L36a | -0.0279411 |
| RPL27A | ribosomal protein L27a | -0.0275008 |
| S100A9 | S100 calcium binding protein A9 | -0.0274987 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0274711 |
| RPL31 | ribosomal protein L31 | -0.02737 |
| CCNI | cyclin I | -0.0273091 |
| PFN1 | profilin 1 | -0.0273063 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0270451 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0269351 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0269187 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0267618 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0266912 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0266266 |
| CAVIN1 | caveolae associated protein 1 | -0.0265912 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0264324 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0258277 |
| RPS20 | ribosomal protein S20 | -0.0256652 |
| BPTF | bromodomain PHD finger transcription factor | -0.0254938 |
| S100A10 | S100 calcium binding protein A10 | -0.0254011 |
| TXNRD1 | thioredoxin reductase 1 | -0.0251293 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.025085 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0249755 |
| RPL13A | ribosomal protein L13a | -0.0249158 |
| RPS16 | ribosomal protein S16 | -0.0246122 |
| RPL36 | ribosomal protein L36 | -0.0245965 |
| NOP58 | NOP58 ribonucleoprotein | -0.024573 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0243558 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0241145 |
| ZNF33A | zinc finger protein 33A | -0.0241029 |
| RCC1 | regulator of chromosome condensation 1 | -0.0240864 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0238881 |
| RPL7A | ribosomal protein L7a | -0.0233098 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0231297 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0230826 |
| TMEM123 | transmembrane protein 123 | -0.022929 |
| RPL5 | ribosomal protein L5 | -0.0228571 |
| CDK12 | cyclin-dependent kinase 12 | -0.0227976 |
| TPD52 | tumor protein D52 | -0.0227286 |
