Osteoarthritis Gene Set

Dataset DISEASES Curated Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. (Experimental Factor Ontology, EFO_0002506)
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Genes

7 genes involed in the disease Osteoarthritis from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ASTN2 astrotactin 2 5.0
NCOA3 nuclear receptor coactivator 3 5.0
COL11A1 collagen, type XI, alpha 1 5.0
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 5.0
MCF2L MCF.2 cell line derived transforming sequence-like 5.0
DOT1L DOT1-like histone H3K79 methyltransferase 5.0
GDF5 growth differentiation factor 5 5.0