Osteoarthrosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0086743
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Genes

118 genes associated with the disease Osteoarthrosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACAN aggrecan
ACO1 aconitase 1, soluble
ACTB actin, beta
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRG2 adhesion G protein-coupled receptor G2
AGER advanced glycosylation end product-specific receptor
AK4 adenylate kinase 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ASPN asporin
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BMPR1A bone morphogenetic protein receptor, type IA
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CDKN2A cyclin-dependent kinase inhibitor 2A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC1 chloride intracellular channel 1
CLIC4 chloride intracellular channel 4
CLU clusterin
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
COL6A2 collagen, type VI, alpha 2
COL9A1 collagen, type IX, alpha 1
COMP cartilage oligomeric matrix protein
CTSD cathepsin D
CTSK cathepsin K
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL6 chemokine (C-X-C motif) ligand 6
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DPEP1 dipeptidase 1 (renal)
DPYSL2 dihydropyrimidinase-like 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EEF2 eukaryotic translation elongation factor 2
ENO1 enolase 1, (alpha)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERRFI1 ERBB receptor feedback inhibitor 1
ESD esterase D
ETFA electron-transfer-flavoprotein, alpha polypeptide
EZR ezrin
FGF18 fibroblast growth factor 18
FRZB frizzled-related protein
FTL ferritin, light polypeptide
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GDF5 growth differentiation factor 5
GLS glutaminase
GSTK1 glutathione S-transferase kappa 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IHH indian hedgehog
IL1B interleukin 1, beta
IMMT inner membrane protein, mitochondrial
ISOC2 isochorismatase domain containing 2
LTBP3 latent transforming growth factor beta binding protein 3
MATN3 matrilin 3
MMP13 matrix metallopeptidase 13
MSN moesin
MVP major vault protein
MYH13 myosin, heavy chain 13, skeletal muscle
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NFE2L2 nuclear factor, erythroid 2-like 2
NME2 NME/NM23 nucleoside diphosphate kinase 2
OPA1 optic atrophy 1 (autosomal dominant)
P3H3 prolyl 3-hydroxylase 3
PDCD6IP programmed cell death 6 interacting protein
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PLCD1 phospholipase C, delta 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLS3 plastin 3
POU3F3 POU class 3 homeobox 3
PPARG peroxisome proliferator-activated receptor gamma
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAN RAN, member RAS oncogene family
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RUNX2 runt-related transcription factor 2
S100A4 S100 calcium binding protein A4
SCRN1 secernin 1
SDCBP syndecan binding protein (syntenin)
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC23A Sec23 homolog A (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMAD3 SMAD family member 3
SOD2 superoxide dismutase 2, mitochondrial
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAP1 TNF receptor-associated protein 1
TRIM2 tripartite motif containing 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TXNRD1 thioredoxin reductase 1
TXNRD2 thioredoxin reductase 2
VDAC2 voltage-dependent anion channel 2
VIM vimentin
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta