Osteochondrosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An ischemic bone disease that results_in necrosis followed by regrowth in children and teens located_in bone. (Human Disease Ontology, DOID_8125)
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Genes

162 genes co-occuring with the disease Osteochondrosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
COL2A1 collagen, type II, alpha 1 2.737
ACAN aggrecan 2.41
COL9A3 collagen, type IX, alpha 3 2.104
CCDC90B coiled-coil domain containing 90B 2.023
COL9A2 collagen, type IX, alpha 2 1.996
COL9A1 collagen, type IX, alpha 1 1.979
SOX9 SRY (sex determining region Y)-box 9 1.967
CLCN2 chloride channel, voltage-sensitive 2 1.957
IGF1 insulin-like growth factor 1 (somatomedin C) 1.916
GALNS galactosamine (N-acetyl)-6-sulfatase 1.915
MMP13 matrix metallopeptidase 13 1.91
BMP2 bone morphogenetic protein 2 1.871
CRP C-reactive protein, pentraxin-related 1.856
COMP cartilage oligomeric matrix protein 1.833
RUNX2 runt-related transcription factor 2 1.831
BGLAP bone gamma-carboxyglutamate (gla) protein 1.821
WBP11 WW domain binding protein 11 1.817
IHH indian hedgehog 1.807
PTH parathyroid hormone 1.781
COL24A1 collagen, type XXIV, alpha 1 1.726
LCORL ligand dependent nuclear receptor corepressor-like 1.724
SLC26A2 solute carrier family 26 (anion exchanger), member 2 1.721
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.721
COL10A1 collagen, type X, alpha 1 1.72
MATN3 matrilin 3 1.704
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.675
TRPS1 trichorhinophalangeal syndrome I 1.672
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 1.667
IL1B interleukin 1, beta 1.637
MMP3 matrix metallopeptidase 3 1.623
ARSK arylsulfatase family, member K 1.614
IL6 interleukin 6 1.592
PRG4 proteoglycan 4 1.586
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.539
F2 coagulation factor II (thrombin) 1.536
COL1A1 collagen, type I, alpha 1 1.534
COL1A2 collagen, type I, alpha 2 1.522
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.52
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 1.508
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1.506
TRAPPC2 trafficking protein particle complex 2 1.505
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 1.499
LYG2 lysozyme G-like 2 1.498
XIRP2 xin actin binding repeat containing 2 1.492
COL11A2 collagen, type XI, alpha 2 1.489
PTH1R parathyroid hormone 1 receptor 1.483
ACP5 acid phosphatase 5, tartrate resistant 1.474
TNF tumor necrosis factor 1.472
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 1.449
TGFB1 transforming growth factor, beta 1 1.431
FAF1 Fas (TNFRSF6) associated factor 1 1.424
SOX5 SRY (sex determining region Y)-box 5 1.422
MECR mitochondrial trans-2-enoyl-CoA reductase 1.411
COL11A1 collagen, type XI, alpha 1 1.4
LEP leptin 1.384
F5 coagulation factor V (proaccelerin, labile factor) 1.378
PAX1 paired box 1 1.373
NCDN neurochondrin 1.373
PTHLH parathyroid hormone-like hormone 1.371
PTH2R parathyroid hormone 2 receptor 1.37
ARSB arylsulfatase B 1.37
INS insulin 1.35
CFAP20 cilia and flagella associated protein 20 1.35
FAM184B family with sequence similarity 184, member B 1.349
DMRT3 doublesex and mab-3 related transcription factor 3 1.327
AOAH acyloxyacyl hydrolase (neutrophil) 1.319
GGN gametogenetin 1.311
LLPH LLP homolog, long-term synaptic facilitation (Aplysia) 1.297
TBC1D22A TBC1 domain family, member 22A 1.286
MATN1 matrilin 1, cartilage matrix protein 1.286
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.286
EXT1 exostosin glycosyltransferase 1 1.283
FBXO25 F-box protein 25 1.28
SOST sclerostin 1.277
ANKRD42 ankyrin repeat domain 42 1.277
MT3 metallothionein 3 1.271
TBX5 T-box 5 1.27
BCAP29 B-cell receptor-associated protein 29 1.259
ALB albumin 1.259
KRT25 keratin 25, type I 1.257
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.252
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 1.246
COL5A1 collagen, type V, alpha 1 1.243
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.237
COL5A2 collagen, type V, alpha 2 1.229
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.228
SMR3A submaxillary gland androgen regulated protein 3A 1.219
FGF5 fibroblast growth factor 5 1.218
CTSK cathepsin K 1.218
FGF18 fibroblast growth factor 18 1.218
BNC2 basonuclin 2 1.217
UFSP2 UFM1-specific peptidase 2 1.216
TMSB4X thymosin beta 4, X-linked 1.212
FGF6 fibroblast growth factor 6 1.207
FGF4 fibroblast growth factor 4 1.202
BGN biglycan 1.197
FGF3 fibroblast growth factor 3 1.194
FGF22 fibroblast growth factor 22 1.19
FGF16 fibroblast growth factor 16 1.188
FGF20 fibroblast growth factor 20 1.185
FGF17 fibroblast growth factor 17 1.183
FGF9 fibroblast growth factor 9 1.17
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 1.167
LBX1 ladybird homeobox 1 1.166
FGF8 fibroblast growth factor 8 (androgen-induced) 1.165
SPP1 secreted phosphoprotein 1 1.163
FGF10 fibroblast growth factor 10 1.16
GH1 growth hormone 1 1.155
FGF2 fibroblast growth factor 2 (basic) 1.152
VWC2 von Willebrand factor C domain containing 2 1.15
IL1A interleukin 1, alpha 1.149
NOS3 nitric oxide synthase 3 (endothelial cell) 1.149
ENG endoglin 1.144
GDF5 growth differentiation factor 5 1.142
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli) 1.14
THY1 Thy-1 cell surface antigen 1.14
IL1RN interleukin 1 receptor antagonist 1.139
TGFB3 transforming growth factor, beta 3 1.139
FGF7 fibroblast growth factor 7 1.136
HP haptoglobin 1.129
FBN2 fibrillin 2 1.119
CCDC91 coiled-coil domain containing 91 1.115
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.113
LUM lumican 1.104
UGDH UDP-glucose 6-dehydrogenase 1.099
FGFR3 fibroblast growth factor receptor 3 1.096
FRZB frizzled-related protein 1.089
TRAFD1 TRAF-type zinc finger domain containing 1 1.087
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.078
GOLGA5 golgin A5 1.077
CLCA4 chloride channel accessory 4 1.071
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.069
SOX6 SRY (sex determining region Y)-box 6 1.066
GLB1 galactosidase, beta 1 1.064
RAB30 RAB30, member RAS oncogene family 1.064
CADPS2 Ca++-dependent secretion activator 2 1.063
MMP1 matrix metallopeptidase 1 1.061
MMP16 matrix metallopeptidase 16 (membrane-inserted) 1.047
DLEU7 deleted in lymphocytic leukemia, 7 1.047
TAC1 tachykinin, precursor 1 1.047
DCN decorin 1.046
IBSP integrin-binding sialoprotein 1.046
FKBP10 FK506 binding protein 10, 65 kDa 1.042
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.037
ASPN asporin 1.035
FGF23 fibroblast growth factor 23 1.034
CKM creatine kinase, muscle 1.031
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 1.031
TLK2 tousled-like kinase 2 1.031
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.029
GH2 growth hormone 2 1.029
MGP matrix Gla protein 1.018
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 1.017
APOF apolipoprotein F 1.016
COL3A1 collagen, type III, alpha 1 1.013
CKMT1B creatine kinase, mitochondrial 1B 1.013
CKB creatine kinase, brain 1.011
PPP1R36 protein phosphatase 1, regulatory subunit 36 1.01
COL27A1 collagen, type XXVII, alpha 1 1.01
ELN elastin 1.007
SECTM1 secreted and transmembrane 1 1.006
SP7 Sp7 transcription factor 1.0