Osteolysis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Osteolysis refers to the destruction of bone through bone resorption with removal or loss of calcium. (Human Phenotype Ontology, HP_0002797)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010014
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Genes

32 genes/proteins associated with the disease Osteolysis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.88009
SPP1 secreted phosphoprotein 1 2.88009
IBSP integrin-binding sialoprotein 2.88009
PTHLH parathyroid hormone-like hormone 2.88009
ANTXR2 anthrax toxin receptor 2 2.88009
TNF tumor necrosis factor 2.88009
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.88009
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.41174
BCL2L1 BCL2-like 1 1.31208
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.27224
COL1A1 collagen, type I, alpha 1 1.25776
BCL2 B-cell CLL/lymphoma 2 1.22853
PARP1 poly (ADP-ribose) polymerase 1 1.2279
PECAM1 platelet/endothelial cell adhesion molecule 1 1.22306
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.21173
H2AFX H2A histone family, member X 1.21043
BAD BCL2-associated agonist of cell death 1.20946
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.20493
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.19966
MAPK1 mitogen-activated protein kinase 1 1.18783
MAPK14 mitogen-activated protein kinase 14 1.15492
BAX BCL2-associated X protein 1.13041
CFLAR CASP8 and FADD-like apoptosis regulator 1.11877
VEGFA vascular endothelial growth factor A 1.09332
JUN jun proto-oncogene 1.09297
MAPK3 mitogen-activated protein kinase 3 1.05864
IL6 interleukin 6 1.04868
CRP C-reactive protein, pentraxin-related 1.04647
CCL2 chemokine (C-C motif) ligand 2 1.04051
FGF2 fibroblast growth factor 2 (basic) 1.02821
MCL1 myeloid cell leukemia 1 1.02485
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.0189