Osteolysis_Leukocyte - Lymphocyte - B-Lymphocyte - Plasma Cell (MMHCC)_GSE755 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE755
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Genes

600 genes differentially expressed during Osteolysis_Leukocyte - Lymphocyte - B-Lymphocyte - Plasma Cell (MMHCC)_GSE755 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
NUDC nudC nuclear distribution protein 2.55267
RPP38 ribonuclease P/MRP 38kDa subunit 2.53618
USP8 ubiquitin specific peptidase 8 2.47258
CDC34 cell division cycle 34 2.45553
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 2.41736
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.36757
PRPF18 pre-mRNA processing factor 18 2.35969
CIAPIN1 cytokine induced apoptosis inhibitor 1 2.30307
FOXK2 forkhead box K2 2.28664
LMF2 lipase maturation factor 2 2.27598
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 2.2508
DEXI Dexi homolog (mouse) 2.22389
ATG14 autophagy related 14 2.21611
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.21186
GAPVD1 GTPase activating protein and VPS9 domains 1 2.20459
UGP2 UDP-glucose pyrophosphorylase 2 2.19145
CCT4 chaperonin containing TCP1, subunit 4 (delta) 2.18823
RPP14 ribonuclease P/MRP 14kDa subunit 2.17885
TP53BP1 tumor protein p53 binding protein 1 2.16977
NMT1 N-myristoyltransferase 1 2.16403
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.15202
SZT2 seizure threshold 2 homolog (mouse) 2.14607
DOLK dolichol kinase 2.13841
PMPCA peptidase (mitochondrial processing) alpha 2.13532
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 2.10404
PKD1 polycystic kidney disease 1 (autosomal dominant) 2.10065
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.09448
TCP1 t-complex 1 2.07782
TRIM32 tripartite motif containing 32 2.06266
LMAN2 lectin, mannose-binding 2 2.04793
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.04672
HIRIP3 HIRA interacting protein 3 2.04103
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 2.03955
TBPL1 TBP-like 1 2.01645
RBL2 retinoblastoma-like 2 2.01632
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 2.01516
KDR kinase insert domain receptor 1.99594
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 1.99381
USP34 ubiquitin specific peptidase 34 1.99234
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 1.98599
API5 apoptosis inhibitor 5 1.98533
SCN2A sodium channel, voltage gated, type II alpha subunit 1.97896
CYHR1 cysteine/histidine-rich 1 1.97712
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 1.96631
BRD1 bromodomain containing 1 1.95999
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 1.94841
BAG6 BCL2-associated athanogene 6 1.94776
MOGS mannosyl-oligosaccharide glucosidase 1.94288
IL10RB interleukin 10 receptor, beta 1.94023
DUT deoxyuridine triphosphatase 1.93464
E2F6 E2F transcription factor 6 1.91866
PGGT1B protein geranylgeranyltransferase type I, beta subunit 1.90654
RCE1 Ras converting CAAX endopeptidase 1 1.90351
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 1.89654
TUBA4A tubulin, alpha 4a 1.89517
MATR3 matrin 3 1.89187
PNN pinin, desmosome associated protein 1.88961
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 1.88641
UBA2 ubiquitin-like modifier activating enzyme 2 1.88035
SYNPO synaptopodin 1.86916
DYNLT1 dynein, light chain, Tctex-type 1 1.86446
CDC23 cell division cycle 23 1.85874
ZNF623 zinc finger protein 623 1.85628
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 1.85549
MAP3K4 mitogen-activated protein kinase kinase kinase 4 1.85073
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 1.84969
HSF2 heat shock transcription factor 2 1.83455
ANKLE2 ankyrin repeat and LEM domain containing 2 1.83308
TRIM28 tripartite motif containing 28 1.8325
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.83171
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.82951
BIRC5 baculoviral IAP repeat containing 5 1.82596
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 1.82287
C1D C1D nuclear receptor corepressor 1.82157
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.81646
TOP3B topoisomerase (DNA) III beta 1.8164
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 1.81357
SYMPK symplekin 1.80763
CPB1 carboxypeptidase B1 (tissue) 1.7979
PRPF31 pre-mRNA processing factor 31 1.7963
ATG5 autophagy related 5 1.79414
FOLR1 folate receptor 1 (adult) 1.792
DPYSL4 dihydropyrimidinase-like 4 1.78928
RAB11FIP2 RAB11 family interacting protein 2 (class I) 1.78903
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.78852
RABGAP1 RAB GTPase activating protein 1 1.7857
NBEAL2 neurobeachin-like 2 1.7854
AGGF1 angiogenic factor with G patch and FHA domains 1 1.78465
HSPE1 heat shock 10kDa protein 1 1.77819
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.77768
ATF2 activating transcription factor 2 1.77603
NUP160 nucleoporin 160kDa 1.77169
DRG2 developmentally regulated GTP binding protein 2 1.76972
GALK2 galactokinase 2 1.76872
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.76516
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 1.75918
SRRD SRR1 domain containing 1.75621
ARID4A AT rich interactive domain 4A (RBP1-like) 1.75329
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 1.75324
LYRM1 LYR motif containing 1 1.75157
SKIL SKI-like proto-oncogene 1.75145
ARG2 arginase 2 1.74974
BRD8 bromodomain containing 8 1.7474
CHSY1 chondroitin sulfate synthase 1 1.74147
PISD phosphatidylserine decarboxylase 1.72583
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 1.72311
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 1.71883
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 1.71778
SREK1 splicing regulatory glutamine/lysine-rich protein 1 1.71458
ERI2 ERI1 exoribonuclease family member 2 1.7141
NUP188 nucleoporin 188kDa 1.71015
PEX3 peroxisomal biogenesis factor 3 1.70227
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1.69931
PACRG PARK2 co-regulated 1.69893
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 1.69523
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 1.69432
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 1.69391
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 1.69295
HDAC2 histone deacetylase 2 1.68874
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 1.68828
PCGF1 polycomb group ring finger 1 1.68353
PIBF1 progesterone immunomodulatory binding factor 1 1.68278
IFT27 intraflagellar transport 27 1.68085
MAPK14 mitogen-activated protein kinase 14 1.67759
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 1.67757
ZBTB6 zinc finger and BTB domain containing 6 1.67711
CCNC cyclin C 1.67652
DEDD death effector domain containing 1.67635
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 1.67628
ADAM18 ADAM metallopeptidase domain 18 1.67611
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.67554
RPA2 replication protein A2, 32kDa 1.67421
PICALM phosphatidylinositol binding clathrin assembly protein 1.67409
SIAH1 siah E3 ubiquitin protein ligase 1 1.6737
TBC1D5 TBC1 domain family, member 5 1.6732
HELZ helicase with zinc finger 1.67274
DYNLL1 dynein, light chain, LC8-type 1 1.67215
CCKAR cholecystokinin A receptor 1.67183
TELO2 telomere maintenance 2 1.6709
COL19A1 collagen, type XIX, alpha 1 1.66998
WDR73 WD repeat domain 73 1.66892
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 1.66773
CYB5R3 cytochrome b5 reductase 3 1.66751
CTSZ cathepsin Z 1.66572
SUZ12 SUZ12 polycomb repressive complex 2 subunit 1.6651
FANCL Fanconi anemia, complementation group L 1.663
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 1.66071
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 1.66015
MAPK6 mitogen-activated protein kinase 6 1.65569
ZNF787 zinc finger protein 787 1.64885
PI3 peptidase inhibitor 3, skin-derived 1.64761
RBM39 RNA binding motif protein 39 1.64484
RAD23B RAD23 homolog B (S. cerevisiae) 1.64409
NOVA2 neuro-oncological ventral antigen 2 1.64314
ACP2 acid phosphatase 2, lysosomal 1.63851
OSGIN2 oxidative stress induced growth inhibitor family member 2 1.63833
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.63658
ZNF253 zinc finger protein 253 1.63464
KPNA6 karyopherin alpha 6 (importin alpha 7) 1.63172
IFNA10 interferon, alpha 10 1.631
FLT1 fms-related tyrosine kinase 1 1.6275
PRNP prion protein 1.62698
KIF20B kinesin family member 20B 1.62488
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 1.6237
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa 1.62362
C21ORF2 chromosome 21 open reading frame 2 1.62219
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 1.62206
ARPP19 cAMP-regulated phosphoprotein, 19kDa 1.62148
DOCK1 dedicator of cytokinesis 1 1.62017
ADCY6 adenylate cyclase 6 1.6182
MTDH metadherin 1.61384
GTPBP6 GTP binding protein 6 (putative) 1.61339
CRYBB2 crystallin, beta B2 1.61151
GCKR glucokinase (hexokinase 4) regulator 1.61133
IL1RL1 interleukin 1 receptor-like 1 1.61105
GTF2A2 general transcription factor IIA, 2, 12kDa 1.60951
FKBP2 FK506 binding protein 2, 13kDa 1.60678
JRK Jrk homolog (mouse) 1.60313
PER1 period circadian clock 1 1.60224
ALOX12 arachidonate 12-lipoxygenase 1.60113
MRPL33 mitochondrial ribosomal protein L33 1.60046
MYO16 myosin XVI 1.60009
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 1.60002
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.59979
SMYD5 SMYD family member 5 1.59751
PMPCB peptidase (mitochondrial processing) beta 1.59665
CKS2 CDC28 protein kinase regulatory subunit 2 1.59478
ZBTB24 zinc finger and BTB domain containing 24 1.58745
CARS cysteinyl-tRNA synthetase 1.5852
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 1.58411
MDH1 malate dehydrogenase 1, NAD (soluble) 1.58233
ALPP alkaline phosphatase, placental 1.57779
PRDM2 PR domain containing 2, with ZNF domain 1.57643
ASMT acetylserotonin O-methyltransferase 1.57309
HMHB1 histocompatibility (minor) HB-1 1.57257
DPYS dihydropyrimidinase 1.57159
MOB4 MOB family member 4, phocein 1.571
KLHDC10 kelch domain containing 10 1.56926
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.56921
CELA2B chymotrypsin-like elastase family, member 2B 1.56791
CD47 CD47 molecule 1.56724
FOXN2 forkhead box N2 1.56705
COX6C cytochrome c oxidase subunit VIc 1.563
N4BP2L2 NEDD4 binding protein 2-like 2 1.56108
CTNNBIP1 catenin, beta interacting protein 1 1.56101
DCBLD2 discoidin, CUB and LCCL domain containing 2 1.5585
HSPA4 heat shock 70kDa protein 4 1.55759
CYLD cylindromatosis (turban tumor syndrome) 1.55692
ALG8 ALG8, alpha-1,3-glucosyltransferase 1.55491
POFUT1 protein O-fucosyltransferase 1 1.55392
ACAA2 acetyl-CoA acyltransferase 2 1.55304
SLC25A42 solute carrier family 25, member 42 1.54987
TCL1B T-cell leukemia/lymphoma 1B 1.54956
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 1.54795
MGP matrix Gla protein 1.54787
DNM1L dynamin 1-like 1.54742
BOLA2 bolA family member 2 1.54713
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 1.54655
CRLF3 cytokine receptor-like factor 3 1.54535
KTN1 kinectin 1 (kinesin receptor) 1.5435
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.54336
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 1.54223
PRRC1 proline-rich coiled-coil 1 1.5415
MT2A metallothionein 2A 1.54103
ANKRD40 ankyrin repeat domain 40 1.53937
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.53812
PAX3 paired box 3 1.53706
GLE1 GLE1 RNA export mediator 1.53548
SIM2 single-minded family bHLH transcription factor 2 1.53509
TRIM29 tripartite motif containing 29 1.53257
CDH16 cadherin 16, KSP-cadherin 1.53102
KDM5C lysine (K)-specific demethylase 5C 1.53085
MED22 mediator complex subunit 22 1.53041
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 1.52953
INVS inversin 1.52618
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 1.52561
CTF1 cardiotrophin 1 1.52519
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 1.52499
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.52438
ZNF202 zinc finger protein 202 1.52206
RCN2 reticulocalbin 2, EF-hand calcium binding domain 1.51881
GRK1 G protein-coupled receptor kinase 1 1.51696
MAPK7 mitogen-activated protein kinase 7 1.51696
AHSG alpha-2-HS-glycoprotein 1.51694
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.51496
HMGN2 high mobility group nucleosomal binding domain 2 1.51473
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 1.51329
ZNF354A zinc finger protein 354A 1.51261
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 1.5122
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.51182
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 1.51151
ADCY7 adenylate cyclase 7 1.51086
SCML2 sex comb on midleg-like 2 (Drosophila) 1.5054
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 1.50286
FAM175B family with sequence similarity 175, member B 1.50236
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 1.50214
RHD Rh blood group, D antigen 1.5021
SAFB2 scaffold attachment factor B2 1.50204
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 1.50123
CLCNKA chloride channel, voltage-sensitive Ka 1.49914
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 1.49503
MLXIP MLX interacting protein 1.49395
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 1.49384
USP22 ubiquitin specific peptidase 22 1.49278
VARS valyl-tRNA synthetase 1.49247
NCOR2 nuclear receptor corepressor 2 1.49128
CIZ1 CDKN1A interacting zinc finger protein 1 1.49116
DIDO1 death inducer-obliterator 1 1.49038
LARP4 La ribonucleoprotein domain family, member 4 1.4901
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 1.48913
DRD4 dopamine receptor D4 1.4882
RUFY3 RUN and FYVE domain containing 3 1.48801
PSME4 proteasome (prosome, macropain) activator subunit 4 1.48794
SNTA1 syntrophin, alpha 1 1.48725
H2AFX H2A histone family, member X 1.4868
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 1.48461
MOG myelin oligodendrocyte glycoprotein 1.4836
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 1.48347
LAGE3 L antigen family, member 3 1.48274
KLF10 Kruppel-like factor 10 1.48223
URM1 ubiquitin related modifier 1 1.48203
PDIA3 protein disulfide isomerase family A, member 3 1.48165
PTPRK protein tyrosine phosphatase, receptor type, K 1.48156
SIGLEC7 sialic acid binding Ig-like lectin 7 1.48143
DEPDC5 DEP domain containing 5 1.48069
ZNF146 zinc finger protein 146 1.48011
HARS histidyl-tRNA synthetase 1.47855
CYB561D2 cytochrome b561 family, member D2 1.47835
SP100 SP100 nuclear antigen 1.47775
RPA3 replication protein A3, 14kDa 1.47635
HIP1R huntingtin interacting protein 1 related 1.47632
RABGGTA Rab geranylgeranyltransferase, alpha subunit 1.47528
STK10 serine/threonine kinase 10 1.47201
WBP1L WW domain binding protein 1-like 1.471
XPC xeroderma pigmentosum, complementation group C 1.46924
KRT12 keratin 12, type I 1.46828
U2AF2 U2 small nuclear RNA auxiliary factor 2 1.46823
GP5 glycoprotein V (platelet) 1.46779
MAP2K4 mitogen-activated protein kinase kinase 4 1.46728
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.46694

decreased expression

Symbol Name Standardized Value
CASC3 cancer susceptibility candidate 3 -2.62211
TOX4 TOX high mobility group box family member 4 -2.54831
FAM178A family with sequence similarity 178, member A -2.53286
EFNA3 ephrin-A3 -2.50359
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 -2.45531
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.43162
FAM168B family with sequence similarity 168, member B -2.40164
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) -2.35249
AKR1C4 aldo-keto reductase family 1, member C4 -2.34823
ATR ATR serine/threonine kinase -2.30292
AAMP angio-associated, migratory cell protein -2.29218
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 -2.282
ARRB2 arrestin, beta 2 -2.26721
KIAA0226 KIAA0226 -2.23876
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.21884
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -2.20842
BBC3 BCL2 binding component 3 -2.20156
PRPF6 pre-mRNA processing factor 6 -2.19361
CALCOCO1 calcium binding and coiled-coil domain 1 -2.18142
PGAM1 phosphoglycerate mutase 1 (brain) -2.17241
DDB1 damage-specific DNA binding protein 1, 127kDa -2.17142
TRBC1 T cell receptor beta constant 1 -2.1689
CYTH2 cytohesin 2 -2.15316
ILVBL ilvB (bacterial acetolactate synthase)-like -2.1471
DOLPP1 dolichyldiphosphatase 1 -2.13994
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -2.13774
SNX4 sorting nexin 4 -2.12046
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -2.08745
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.08617
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -2.07909
ECE2 endothelin converting enzyme 2 -2.07748
DGUOK deoxyguanosine kinase -2.07257
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -2.06122
PHB prohibitin -2.06108
EIF1 eukaryotic translation initiation factor 1 -2.06021
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.05587
SP2 Sp2 transcription factor -2.0463
FAM193A family with sequence similarity 193, member A -2.03637
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.03526
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.02466
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -2.02203
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -2.00555
NUP62 nucleoporin 62kDa -1.99871
DCTN6 dynactin 6 -1.99455
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 -1.99386
SF3A2 splicing factor 3a, subunit 2, 66kDa -1.98848
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -1.97913
JAK1 Janus kinase 1 -1.97605
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 -1.97532
NQO1 NAD(P)H dehydrogenase, quinone 1 -1.96927
TSC22D2 TSC22 domain family, member 2 -1.96817
UCKL1 uridine-cytidine kinase 1-like 1 -1.96299
TFE3 transcription factor binding to IGHM enhancer 3 -1.95856
SEC24C SEC24 family member C -1.95129
U2SURP U2 snRNP-associated SURP domain containing -1.94799
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -1.9415
STIM1 stromal interaction molecule 1 -1.93754
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -1.9341
ZNF324 zinc finger protein 324 -1.93214
FMO4 flavin containing monooxygenase 4 -1.92435
PLCG1 phospholipase C, gamma 1 -1.92004
BICD1 bicaudal D homolog 1 (Drosophila) -1.91915
ACLY ATP citrate lyase -1.91868
IL10 interleukin 10 -1.91687
LOC100507424 uncharacterized LOC100507424 -1.91483
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -1.90901
CLASP2 cytoplasmic linker associated protein 2 -1.90886
LTBP4 latent transforming growth factor beta binding protein 4 -1.90813
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -1.90723
SLCO2A1 solute carrier organic anion transporter family, member 2A1 -1.90293
OXSR1 oxidative stress responsive 1 -1.90134
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 -1.89573
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -1.87958
DVL3 dishevelled segment polarity protein 3 -1.87278
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -1.87142
GDE1 glycerophosphodiester phosphodiesterase 1 -1.87057
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -1.86942
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -1.85192
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -1.85073
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -1.84611
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 -1.84563
AHCTF1 AT hook containing transcription factor 1 -1.84301
DZIP3 DAZ interacting zinc finger protein 3 -1.84191
CENPI centromere protein I -1.83796
CTSB cathepsin B -1.83165
USP9X ubiquitin specific peptidase 9, X-linked -1.83143
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -1.82911
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -1.82726
ZBTB11 zinc finger and BTB domain containing 11 -1.82269
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -1.82087
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -1.81445
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -1.81108
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -1.80822
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -1.80573
ANKRD12 ankyrin repeat domain 12 -1.80009
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -1.79949
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 -1.79901
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -1.79439
UBE2B ubiquitin-conjugating enzyme E2B -1.79367
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -1.78928
CLTC clathrin, heavy chain (Hc) -1.78452
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain -1.78434
KDM4C lysine (K)-specific demethylase 4C -1.78288
AES amino-terminal enhancer of split -1.77813
RET ret proto-oncogene -1.77797
PHF21A PHD finger protein 21A -1.77793
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) -1.77732
CLTCL1 clathrin, heavy chain-like 1 -1.77655
CP ceruloplasmin (ferroxidase) -1.77653
SEC23IP SEC23 interacting protein -1.7761
CHD4 chromodomain helicase DNA binding protein 4 -1.77606
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -1.77367
NDRG2 NDRG family member 2 -1.77014
NPHP4 nephronophthisis 4 -1.76968
IFT20 intraflagellar transport 20 -1.766
RSRC2 arginine/serine-rich coiled-coil 2 -1.76559
C2CD3 C2 calcium-dependent domain containing 3 -1.7605
DSTN destrin (actin depolymerizing factor) -1.75961
BRMS1 breast cancer metastasis suppressor 1 -1.75632
ZBED1 zinc finger, BED-type containing 1 -1.75325
NFE2L1 nuclear factor, erythroid 2-like 1 -1.75037
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -1.74988
PPP1R13B protein phosphatase 1, regulatory subunit 13B -1.74898
KLF5 Kruppel-like factor 5 (intestinal) -1.74744
DOCK2 dedicator of cytokinesis 2 -1.74506
ATXN7L3B ataxin 7-like 3B -1.74495
FKBP1A FK506 binding protein 1A, 12kDa -1.73799
PCDH1 protocadherin 1 -1.73646
TBKBP1 TBK1 binding protein 1 -1.73633
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 -1.73501
CBR3 carbonyl reductase 3 -1.73261
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -1.72495
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -1.72358
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -1.72311
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -1.72181
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -1.72156
PIAS3 protein inhibitor of activated STAT, 3 -1.7198
SPATA2 spermatogenesis associated 2 -1.71961
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -1.71731
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -1.71149
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.71063
MSN moesin -1.71025
RHOG ras homolog family member G -1.70919
RIN1 Ras and Rab interactor 1 -1.70866
MRPL3 mitochondrial ribosomal protein L3 -1.70703
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 -1.70563
TXLNA taxilin alpha -1.70554
SEC14L2 SEC14-like 2 (S. cerevisiae) -1.70503
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -1.70195
GLP1R glucagon-like peptide 1 receptor -1.70157
GPA33 glycoprotein A33 (transmembrane) -1.69371
RXRG retinoid X receptor, gamma -1.69348
CD2AP CD2-associated protein -1.68867
OCRL oculocerebrorenal syndrome of Lowe -1.68666
HACD2 3-hydroxyacyl-CoA dehydratase 2 -1.68654
ELF2 E74-like factor 2 (ets domain transcription factor) -1.68384
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 -1.68377
APOE apolipoprotein E -1.68264
LRP10 low density lipoprotein receptor-related protein 10 -1.67851
H1FX H1 histone family, member X -1.67341
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -1.67324
ZNF212 zinc finger protein 212 -1.67139
ITGAV integrin, alpha V -1.67012
WBP4 WW domain binding protein 4 -1.66768
OPN1SW opsin 1 (cone pigments), short-wave-sensitive -1.66489
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled -1.66351
OMG oligodendrocyte myelin glycoprotein -1.66226
ZFP36L1 ZFP36 ring finger protein-like 1 -1.65905
NCAPH2 non-SMC condensin II complex, subunit H2 -1.65757
RALBP1 ralA binding protein 1 -1.6542
ACD adrenocortical dysplasia homolog (mouse) -1.65367
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.65116
KRAS Kirsten rat sarcoma viral oncogene homolog -1.65022
GDI1 GDP dissociation inhibitor 1 -1.64851
SCP2 sterol carrier protein 2 -1.64631
HOXA4 homeobox A4 -1.64181
ZNF646 zinc finger protein 646 -1.64136
KYNU kynureninase -1.63939
TMEM41B transmembrane protein 41B -1.63721
AP1B1 adaptor-related protein complex 1, beta 1 subunit -1.63543
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -1.63377
ZC3H3 zinc finger CCCH-type containing 3 -1.63137
PCDHA13 protocadherin alpha 13 -1.62857
ADAM15 ADAM metallopeptidase domain 15 -1.62854
ALPL alkaline phosphatase, liver/bone/kidney -1.62413
HMGN4 high mobility group nucleosomal binding domain 4 -1.62401
RBMS2 RNA binding motif, single stranded interacting protein 2 -1.62247
STARD3 StAR-related lipid transfer (START) domain containing 3 -1.6216
SETD3 SET domain containing 3 -1.61708
STARD7 StAR-related lipid transfer (START) domain containing 7 -1.61585
VAMP4 vesicle-associated membrane protein 4 -1.61507
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit -1.61461
ICK intestinal cell (MAK-like) kinase -1.61384
FOXJ2 forkhead box J2 -1.61351
SULT4A1 sulfotransferase family 4A, member 1 -1.61035
SEC23B Sec23 homolog B (S. cerevisiae) -1.60809
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -1.60489
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -1.60447
MICB MHC class I polypeptide-related sequence B -1.60415
YPEL1 yippee-like 1 (Drosophila) -1.60189
CTSO cathepsin O -1.60025
ZNF259P1 zinc finger protein 259 pseudogene 1 -1.59969
DOT1L DOT1-like histone H3K79 methyltransferase -1.59797
ALAS1 5'-aminolevulinate synthase 1 -1.59779
STAU1 staufen double-stranded RNA binding protein 1 -1.59723
ERCC3 excision repair cross-complementation group 3 -1.59671
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -1.5966
MCL1 myeloid cell leukemia 1 -1.59098
ZFP36 ZFP36 ring finger protein -1.58918
NGDN neuroguidin, EIF4E binding protein -1.58763
BTN2A1 butyrophilin, subfamily 2, member A1 -1.58718
PLLP plasmolipin -1.58346
ZNF467 zinc finger protein 467 -1.58213
FAS Fas cell surface death receptor -1.58123
DPYSL3 dihydropyrimidinase-like 3 -1.58068
HLA-A major histocompatibility complex, class I, A -1.58047
ACBD3 acyl-CoA binding domain containing 3 -1.57951
CBR4 carbonyl reductase 4 -1.57601
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -1.57404
BLM Bloom syndrome, RecQ helicase-like -1.57307
KAT7 K(lysine) acetyltransferase 7 -1.57264
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -1.57228
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) -1.57142
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.56982
AKT1 v-akt murine thymoma viral oncogene homolog 1 -1.56663
CSNK2A1 casein kinase 2, alpha 1 polypeptide -1.5596
TMEM151B transmembrane protein 151B -1.55383
LIPC lipase, hepatic -1.54774
CD59 CD59 molecule, complement regulatory protein -1.54094
PRKCSH protein kinase C substrate 80K-H -1.54043
PSKH1 protein serine kinase H1 -1.53928
CNOT1 CCR4-NOT transcription complex, subunit 1 -1.53605
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -1.536
DKC1 dyskeratosis congenita 1, dyskerin -1.53456
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -1.53436
CNR2 cannabinoid receptor 2 (macrophage) -1.53234
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -1.53218
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -1.53198
CDC42 cell division cycle 42 -1.52911
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -1.52846
MAT1A methionine adenosyltransferase I, alpha -1.52756
COPS8 COP9 signalosome subunit 8 -1.52726
ARC activity-regulated cytoskeleton-associated protein -1.52674
MXD1 MAX dimerization protein 1 -1.52484
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -1.52428
IL32 interleukin 32 -1.52328
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -1.52168
LAMP1 lysosomal-associated membrane protein 1 -1.52158
RNF44 ring finger protein 44 -1.51919
IL1R1 interleukin 1 receptor, type I -1.51705
PML promyelocytic leukemia -1.51487
NEFL neurofilament, light polypeptide -1.51481
ZNF32 zinc finger protein 32 -1.51357
CLASP1 cytoplasmic linker associated protein 1 -1.51283
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -1.51152
METTL7A methyltransferase like 7A -1.5099
GLS glutaminase -1.50876
NTF3 neurotrophin 3 -1.50776
HCLS1 hematopoietic cell-specific Lyn substrate 1 -1.50422
SSTR3 somatostatin receptor 3 -1.50409
MNT MAX network transcriptional repressor -1.5034
TUBB3 tubulin, beta 3 class III -1.50263
LTB lymphotoxin beta (TNF superfamily, member 3) -1.50225
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 -1.50161
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 -1.497
PARP1 poly (ADP-ribose) polymerase 1 -1.49628
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -1.49431
FGR FGR proto-oncogene, Src family tyrosine kinase -1.49352
PNLIPRP1 pancreatic lipase-related protein 1 -1.49173
SULF1 sulfatase 1 -1.49144
SEPW1 selenoprotein W, 1 -1.48855
RANBP1 RAN binding protein 1 -1.48626
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E -1.48626
SNCG synuclein, gamma (breast cancer-specific protein 1) -1.48475
SUMO3 small ubiquitin-like modifier 3 -1.48453
GMPS guanine monphosphate synthase -1.48248
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) -1.47978
CFHR3 complement factor H-related 3 -1.47973
RBM15B RNA binding motif protein 15B -1.47911
KLK6 kallikrein-related peptidase 6 -1.47837
PRODH2 proline dehydrogenase (oxidase) 2 -1.46885
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -1.46513
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 -1.46512
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) -1.46251
POU2F3 POU class 2 homeobox 3 -1.45907
CHRND cholinergic receptor, nicotinic, delta (muscle) -1.4578
KIF1A kinesin family member 1A -1.45708
TCOF1 Treacher Collins-Franceschetti syndrome 1 -1.45296
HMGXB3 HMG box domain containing 3 -1.45175
TCTA T-cell leukemia translocation altered -1.45046
ACTN3 actinin, alpha 3 (gene/pseudogene) -1.44969
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 -1.44867
PTOV1-AS1 PTOV1 antisense RNA 1 -1.44793
MTA1 metastasis associated 1 -1.4476
ZNF133 zinc finger protein 133 -1.44619
GJA8 gap junction protein, alpha 8, 50kDa -1.44599
RHOD ras homolog family member D -1.44508
PMP22 peripheral myelin protein 22 -1.44384
SRSF6 serine/arginine-rich splicing factor 6 -1.44304
CD2 CD2 molecule -1.44289
Funding