Osteomalacia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A bone remodeling disease that has_material_basis_in a vitamin D deficiency which results_in softening located_in bone. (Human Disease Ontology, DOID_10573)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010018
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Genes

29 genes/proteins associated with the disease Osteomalacia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
MEPE matrix extracellular phosphoglycoprotein 2.88009
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.28734
AR androgen receptor 1.24118
ACTA1 actin, alpha 1, skeletal muscle 1.23074
PTH parathyroid hormone 1.19639
POU3F1 POU class 3 homeobox 1 1.19607
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.17134
CXCL8 chemokine (C-X-C motif) ligand 8 1.16104
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 1.13075
GLUL glutamate-ammonia ligase 1.12185
S100A8 S100 calcium binding protein A8 1.12048
GPX2 glutathione peroxidase 2 1.11775
RPA2 replication protein A2, 32kDa 1.10942
SPP1 secreted phosphoprotein 1 1.10803
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.10562
CDA cytidine deaminase 1.10388
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.09262
TPD52L1 tumor protein D52-like 1 1.08407
E2F1 E2F transcription factor 1 1.08126
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.08091
CD14 CD14 molecule 1.07199
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.05535
GNPDA2 glucosamine-6-phosphate deaminase 2 1.05386
IGF1 insulin-like growth factor 1 (somatomedin C) 1.04465
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 1.04014
MMP1 matrix metallopeptidase 1 1.02596
IL6 interleukin 6 1.02559
TNF tumor necrosis factor 1.02114
VIM vimentin 1.01437