Osteopenia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Osteopenia refers to a reduction in bone mineral density (BMD) below normal peak BMD but not low enough to be classified as osteoporosis. According to the WHO, osteopenia is characterized by a value of BMD more than 1 standard deviation below the young adult mean, but less than 2 standard deviations below this value. (Human Phenotype Ontology, HP_0000938)
External Link https://www.disgenet.org/browser/0/1/0/C0029453
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Genes

791 genes associated with the disease Osteopenia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABI1 abl-interactor 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACAD8 acyl-CoA dehydrogenase family, member 8
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACKR2 atypical chemokine receptor 2
ACP5 acid phosphatase 5, tartrate resistant
ACR acrosin
ACTB actin, beta
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTSL2 ADAMTS-like 2
ADCY10 adenylate cyclase 10 (soluble)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADORA2B adenosine A2b receptor
AFG3L2 AFG3-like AAA ATPase 2
AGBL2 ATP/GTP binding protein-like 2
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGXT2 alanine--glyoxylate aminotransferase 2
AHR aryl hydrocarbon receptor
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AHSG alpha-2-HS-glycoprotein
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AIP aryl hydrocarbon receptor interacting protein
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALPL alkaline phosphatase, liver/bone/kidney
AMBP alpha-1-microglobulin/bikunin precursor
AMELX amelogenin, X-linked
ANGPTL2 angiopoietin-like 2
ANKRD11 ankyrin repeat domain 11
ANO5 anoctamin 5
ANOS1 anosmin 1
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANTXR2 anthrax toxin receptor 2
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMC9 armadillo repeat containing 9
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
ASCC2 activating signal cointegrator 1 complex subunit 2
ASF1A anti-silencing function 1A histone chaperone
ASXL1 additional sex combs like transcriptional regulator 1
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVP arginine vasopressin
B3GAT3 beta-1,3-glucuronyltransferase 3
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL6 B-cell CLL/lymphoma 6
BEST1 bestrophin 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BGN biglycan
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP15 bone morphogenetic protein 15
BMP2 bone morphogenetic protein 2
BMP3 bone morphogenetic protein 3
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD2 bromodomain containing 2
BRD4 bromodomain containing 4
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C1QTNF4 C1q and tumor necrosis factor related protein 4
C4BPA complement component 4 binding protein, alpha
CALCA calcitonin-related polypeptide alpha
CALCR calcitonin receptor
CAMP cathelicidin antimicrobial peptide
CARD14 caspase recruitment domain family, member 14
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCND1 cyclin D1
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CD109 CD109 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD6 CD6 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC73 cell division cycle 73
CDH23 cadherin-related 23
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDX2 caudal type homeobox 2
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAD chondroadherin
CHD7 chromodomain helicase DNA binding protein 7
CHRM3 cholinergic receptor, muscarinic 3
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CIITA class II, major histocompatibility complex, transactivator
CLDN11 claudin 11
CLIP2 CAP-GLY domain containing linker protein 2
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
COG1 component of oligomeric golgi complex 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL7A1 collagen, type VII, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
COX2
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CRBN cereblon
CREB3L1 cAMP responsive element binding protein 3-like 1
CREBBP CREB binding protein
CREM cAMP responsive element modulator
CRIPT cysteine-rich PDZ-binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRTAP cartilage associated protein
CRX cone-rod homeobox
CRYGD crystallin, gamma D
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CST3 cystatin C
CTC1 CTS telomere maintenance complex component 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNS cystinosin, lysosomal cystine transporter
CTSK cathepsin K
CUX1 cut-like homeobox 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
DCAF17 DDB1 and CUL4 associated factor 17
DCHS1 dachsous cadherin-related 1
DCN decorin
DCSTAMP dendrocyte expressed seven transmembrane protein
DCTN4 dynactin 4 (p62)
DDIT3 DNA-damage-inducible transcript 3
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DEFB103A defensin, beta 103A
DEFB103B defensin, beta 103B
DEPTOR DEP domain containing MTOR-interacting protein
DHCR7 7-dehydrocholesterol reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DLX3 distal-less homeobox 3
DMD dystrophin
DMP1 dentin matrix acidic phosphoprotein 1
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21
DNER delta/notch-like EGF repeat containing
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK11 dedicator of cytokinesis 11
DOCK7 dedicator of cytokinesis 7
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DOK3 docking protein 3
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DPP3 dipeptidyl-peptidase 3
DUSP14 dual specificity phosphatase 14
DUSP2 dual specificity phosphatase 2
DUSP6 dual specificity phosphatase 6
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EBI3 Epstein-Barr virus induced 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EED embryonic ectoderm development
EFL1 elongation factor like GTPase 1
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR2 early growth response 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELANE elastase, neutrophil expressed
ELN elastin
EMCN endomucin
ENG endoglin
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
EPO erythropoietin
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERVW-1 endogenous retrovirus group W, member 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRG estrogen-related receptor gamma
ETV6 ets variant 6
EXOC6B exocyst complex component 6B
EXT2 exostosin glycosyltransferase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FARSB phenylalanyl-tRNA synthetase, beta subunit
FAS Fas cell surface death receptor
FASN fatty acid synthase
FAT4 FAT atypical cadherin 4
FBLIM1 filamin binding LIM protein 1
FBN1 fibrillin 1
FBN2 fibrillin 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FFAR1 free fatty acid receptor 1
FFAR2 free fatty acid receptor 2
FGF17 fibroblast growth factor 17
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FHL2 four and a half LIM domains 2
FKBP10 FK506 binding protein 10, 65 kDa
FKBP14 FK506 binding protein 14, 22 kDa
FLG filaggrin
FN1 fibronectin 1
FNDC1 fibronectin type III domain containing 1
FNDC5 fibronectin type III domain containing 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
FTH1 ferritin, heavy polypeptide 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATA1 GATA binding protein 1 (globin transcription factor 1)
GBA glucosidase, beta, acid
GC group-specific component (vitamin D binding protein)
GCM2 glial cells missing homolog 2 (Drosophila)
GDF5 growth differentiation factor 5
GEMIN4 gem (nuclear organelle) associated protein 4
GFI1 growth factor independent 1 transcription repressor
GGCX gamma-glutamyl carboxylase
GGT1 gamma-glutamyltransferase 1
GGTLC3 gamma-glutamyltransferase light chain 3
GH1 growth hormone 1
GHR growth hormone receptor
GIP gastric inhibitory polypeptide
GJA1 gap junction protein, alpha 1, 43kDa
GLI2 GLI family zinc finger 2
GLIS3 GLIS family zinc finger 3
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAS GNAS complex locus
GNPAT glyceronephosphate O-acyltransferase
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GOPC golgi-associated PDZ and coiled-coil motif containing
GORAB golgin, RAB6-interacting
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPBAR1 G protein-coupled bile acid receptor 1
GPR35 G protein-coupled receptor 35
GRAP2 GRB2-related adaptor protein 2
GRN granulin
GSK3B glycogen synthase kinase 3 beta
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2H5 general transcription factor IIH, polypeptide 5
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GZF1 GDNF-inducible zinc finger protein 1
HAMP hepcidin antimicrobial peptide
HAVCR1 hepatitis A virus cellular receptor 1
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBZ hemoglobin, zeta
HDAC4 histone deacetylase 4
HES1 hes family bHLH transcription factor 1
HESX1 HESX homeobox 1
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-B major histocompatibility complex, class I, B
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
HP haptoglobin
HPD 4-hydroxyphenylpyruvate dioxygenase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRAS Harvey rat sarcoma viral oncogene homolog
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSPA14 heat shock 70kDa protein 14
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
ICAM1 intercellular adhesion molecule 1
ICK intestinal cell (MAK-like) kinase
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFITM5 interferon induced transmembrane protein 5
IFNG interferon, gamma
IFRD1 interferon-related developmental regulator 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGFBP1 insulin-like growth factor binding protein 1
IGSF23 immunoglobulin superfamily, member 23
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL11 interleukin 11
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17B interleukin 17B
IL17D interleukin 17D
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL20 interleukin 20
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL27 interleukin 27
IL27RA interleukin 27 receptor, alpha
IL3 interleukin 3
IL32 interleukin 32
IL33 interleukin 33
IL33R interleukin 33 receptor
IL37 interleukin 37
IL4 interleukin 4
IL6 interleukin 6
IL7 interleukin 7
IL9 interleukin 9
IMMT inner membrane protein, mitochondrial
IRF4 interferon regulatory factor 4
IRS2 insulin receptor substrate 2
IRX5 iroquois homeobox 5
KAT2A K(lysine) acetyltransferase 2A
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5A lysine (K)-specific demethylase 5A
KEAP1 kelch-like ECH-associated protein 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIF3A kinesin family member 3A
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KL klotho
KLF10 Kruppel-like factor 10
KLF13 Kruppel-like factor 13
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT8 keratin 8, type II
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS8 lectin, galactoside-binding, soluble, 8
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHX4 LIM homeobox 4
LIFR leukemia inhibitory factor receptor alpha
LIMK1 LIM domain kinase 1
LIMS1 LIM and senescent cell antigen-like domains 1
LIMS2 LIM and senescent cell antigen-like domains 2
LMNA lamin A/C
LOC102724560 cystathionine beta-synthase
LOC105371045 uncharacterized LOC105371045
LRP2 low density lipoprotein receptor-related protein 2
LRP4 low density lipoprotein receptor-related protein 4
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEL2 melanoma antigen family L2
MAOA monoamine oxidase A
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MBTPS2 membrane-bound transcription factor peptidase, site 2
MECOM MDS1 and EVI1 complex locus
MECP2 methyl CpG binding protein 2
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MFAP2 microfibrillar-associated protein 2
MFGE8 milk fat globule-EGF factor 8 protein
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MLXIPL MLX interacting protein-like
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPEG1 macrophage expressed 1
MPLKIP M-phase specific PLK1 interacting protein
MPO myeloperoxidase
MPST mercaptopyruvate sulfurtransferase
MRGPRF MAS-related GPR, member F
MRPS22 mitochondrial ribosomal protein S22
MSC musculin
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MSTN myostatin
MSTO1 misato 1, mitochondrial distribution and morphology regulator
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYSM1 Myb-like, SWIRM and MPN domains 1
NAGA N-acetylgalactosaminidase, alpha-
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCK1 NCK adaptor protein 1
NCOA1 nuclear receptor coactivator 1
NCOA5 nuclear receptor coactivator 5
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGLY1 N-glycanase 1
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOV nephroblastoma overexpressed
NPR2 natriuretic peptide receptor 2
NPY neuropeptide Y
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSD1 nuclear receptor binding SET domain protein 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NT5E 5'-nucleotidase, ecto (CD73)
NUP107 nucleoporin 107kDa
NUP62 nucleoporin 62kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
ORAI1 ORAI calcium release-activated calcium modulator 1
OSM oncostatin M
OSTM1 osteopetrosis associated transmembrane protein 1
OTX2 orthodenticle homeobox 2
OXA1L oxidase (cytochrome c) assembly 1-like
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P3H1 prolyl 3-hydroxylase 1
P4HB prolyl 4-hydroxylase, beta polypeptide
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAH phenylalanine hydroxylase
PAX5 paired box 5
PCNA proliferating cell nuclear antigen
PDE11A phosphodiesterase 11A
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PECAM1 platelet/endothelial cell adhesion molecule 1
PEX6 peroxisomal biogenesis factor 6
PHGDH phosphoglycerate dehydrogenase
PHOSPHO1 phosphatase, orphan 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIFO primary cilia formation
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLG plasminogen
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLS3 plastin 3
PMEL premelanosome protein
PMM2 phosphomannomutase 2
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
PON1 paraoxonase 1
POU1F1 POU class 1 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRDM1 PR domain containing 1, with ZNF domain
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKG2 protein kinase, cGMP-dependent, type II
PRL prolactin
PRLR prolactin receptor
PRMT1 protein arginine methyltransferase 1
PRMT3 protein arginine methyltransferase 3
PRMT5 protein arginine methyltransferase 5
PRNP prion protein
PROK2 prokineticin 2
PROKR2 prokineticin receptor 2
PROP1 PROP paired-like homeobox 1
PRRX1 paired related homeobox 1
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
PSG5 pregnancy specific beta-1-glycoprotein 5
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMC3IP PSMC3 interacting protein
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRA protein tyrosine phosphatase, receptor type, A
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
PURA purine-rich element binding protein A
PYCARD PYD and CARD domain containing
PYCR1 pyrroline-5-carboxylate reductase 1
PYY peptide YY
QRFPR pyroglutamylated RFamide peptide receptor
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RB1CC1 RB1-inducible coiled-coil 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBP4 retinol binding protein 4, plasma
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RECQL4 RecQ protein-like 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RFC2 replication factor C (activator 1) 2, 40kDa
RGN regucalcin
RGS12 regulator of G-protein signaling 12
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHBDL1 rhomboid, veinlet-like 1 (Drosophila)
RIOX1 ribosomal oxygenase 1
RNF113A ring finger protein 113A
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL11 ribosomal protein L11
RPL29 ribosomal protein L29
RPS19 ribosomal protein S19
RPS19BP1 ribosomal protein S19 binding protein 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RRBP1 ribosome binding protein 1
RSAD2 radical S-adenosyl methionine domain containing 2
RSPO1 R-spondin 1
RSPRY1 ring finger and SPRY domain containing 1
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
S100A12 S100 calcium binding protein A12
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
S1PR2 sphingosine-1-phosphate receptor 2
SART3 squamous cell carcinoma antigen recognized by T cells 3
SATB2 SATB homeobox 2
SBDS Shwachman-Bodian-Diamond syndrome
SCARB2 scavenger receptor class B, member 2
SCIN scinderin
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCT secretin
SEC24D SEC24 family member D
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD2 SET domain containing 2
SFRP5 secreted frizzled-related protein 5
SGK1 serum/glucocorticoid regulated kinase 1
SGMS2 sphingomyelin synthase 2
SH3BP2 SH3-domain binding protein 2
SH3PXD2B SH3 and PX domains 2B
SHBG sex hormone-binding globulin
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SIRT6 sirtuin 6
SKI SKI proto-oncogene
SLA Src-like-adaptor
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC39A13 solute carrier family 39 (zinc transporter), member 13
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLIT3 slit homolog 3 (Drosophila)
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SND1 staphylococcal nuclease and tudor domain containing 1
SNX10 sorting nexin 10
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOST sclerostin
SOX3 SRY (sex determining region Y)-box 3
SOX9 SRY (sex determining region Y)-box 9
SPHK1 sphingosine kinase 1
SPIDR scaffolding protein involved in DNA repair
SPP1 secreted phosphoprotein 1
SPRY4 sprouty homolog 4 (Drosophila)
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRP54 signal recognition particle 54kDa
SRY sex determining region Y
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STING1 stimulator of interferon response cGAMP interactor 1
STS steroid sulfatase (microsomal), isozyme S
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SYK spleen tyrosine kinase
SYT1 synaptotagmin I
TAC3 tachykinin 3
TACR3 tachykinin receptor 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAPT1 transmembrane anterior posterior transformation 1
TAT tyrosine aminotransferase
TBL2 transducin (beta)-like 2
TCF4 transcription factor 4
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TET1 tet methylcytosine dioxygenase 1
TEX11 testis expressed 11
TFEB transcription factor EB
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGIF2 TGFB-induced factor homeobox 2
TGM2 transglutaminase 2
THBD thrombomodulin
THY1 Thy-1 cell surface antigen
TIMELESS timeless circadian clock
TLR2 toll-like receptor 2
TLR9 toll-like receptor 9
TMEM38B transmembrane protein 38B
TMEM67 transmembrane protein 67
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNXB tenascin XB
TOB2 transducer of ERBB2, 2
TONSL tonsoku-like, DNA repair protein
TP53 tumor protein p53
TPX2 TPX2, microtubule-associated
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAP triiodothyronine receptor auxiliary protein
TREM1 triggering receptor expressed on myeloid cells 1
TRIM24 tripartite motif containing 24
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRPS1 trichorhinophalangeal syndrome I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC1 tuberous sclerosis 1
TSC22D3 TSC22 domain family, member 3
TSPO translocator protein (18kDa)
TUBB6 tubulin, beta 6 class V
TXLNG taxilin gamma
TXN thioredoxin
TYROBP TYRO protein tyrosine kinase binding protein
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UNC80 unc-80 homolog (C. elegans)
UROS uroporphyrinogen III synthase
USP6 ubiquitin specific peptidase 6
USP9X ubiquitin specific peptidase 9, X-linked
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
VIP vasoactive intestinal peptide
VKORC1 vitamin K epoxide reductase complex, subunit 1
VSIG4 V-set and immunoglobulin domain containing 4
VSX1 visual system homeobox 1
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR11 WD repeat domain 11
WIF1 WNT inhibitory factor 1
WISP3 WNT1 inducible signaling pathway protein 3
WLS wntless Wnt ligand secretion mediator
WNK1 WNK lysine deficient protein kinase 1
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT16 wingless-type MMTV integration site family, member 16
WNT3 wingless-type MMTV integration site family, member 3
WNT5A wingless-type MMTV integration site family, member 5A
XPR1 xenotropic and polytropic retrovirus receptor 1
XYLT2 xylosyltransferase II
YAP1 Yes-associated protein 1
ZFP36 ZFP36 ring finger protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZMPSTE24 zinc metallopeptidase STE24
ZNF384 zinc finger protein 384