Osteopoikilosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An osteosclerosis that results_in numerous bone islands located_in skeleton. (Human Disease Ontology, DOID_11991)
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Genes

92 genes co-occuring with the disease Osteopoikilosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
LEMD3 LEM domain containing 3 3.822
TMEM53 transmembrane protein 53 2.342
EMD emerin 2.155
BANF2 barrier to autointegration factor 2 1.927
OSTM1 osteopetrosis associated transmembrane protein 1 1.919
MSRB3 methionine sulfoxide reductase B3 1.916
LEMD2 LEM domain containing 2 1.893
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.854
HMGA2 high mobility group AT-hook 2 1.851
MAP2K1 mitogen-activated protein kinase kinase 1 1.828
ELN elastin 1.783
CLCN7 chloride channel, voltage-sensitive 7 1.782
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 1.77
LBR lamin B receptor 1.75
SYNE2 spectrin repeat containing, nuclear envelope 2 1.712
BANF1 barrier to autointegration factor 1 1.672
SNX10 sorting nexin 10 1.649
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 1.639
TGFB1 transforming growth factor, beta 1 1.605
AMER1 APC membrane recruitment protein 1 1.596
PLPP7 phospholipid phosphatase 7 (inactive) 1.563
SUN2 Sad1 and UNC84 domain containing 2 1.537
SMAD3 SMAD family member 3 1.536
SUN1 Sad1 and UNC84 domain containing 1 1.526
ANKLE2 ankyrin repeat and LEM domain containing 2 1.52
XPOT exportin, tRNA 1.517
TBC1D30 TBC1 domain family, member 30 1.478
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.477
TOR1AIP2 torsin A interacting protein 2 1.468
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.417
LLPH LLP homolog, long-term synaptic facilitation (Aplysia) 1.414
TM7SF2 transmembrane 7 superfamily member 2 1.414
TMEM135 transmembrane protein 135 1.401
SYNE4 spectrin repeat containing, nuclear envelope family member 4 1.386
SYNE1 spectrin repeat containing, nuclear envelope 1 1.368
EXT2 exostosin glycosyltransferase 2 1.367
IRAK3 interleukin-1 receptor-associated kinase 3 1.362
LRP5 low density lipoprotein receptor-related protein 5 1.352
SMAD9 SMAD family member 9 1.349
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.341
CA2 carbonic anhydrase II 1.341
NRM nurim (nuclear envelope membrane protein) 1.338
SMAD2 SMAD family member 2 1.331
TEX22 testis expressed 22 1.314
KRT1 keratin 1, type II 1.313
RCE1 Ras converting CAAX endopeptidase 1 1.292
EXT1 exostosin glycosyltransferase 1 1.287
UHMK1 U2AF homology motif (UHM) kinase 1 1.282
TMEM38A transmembrane protein 38A 1.28
SP7 Sp7 transcription factor 1.263
ZMPSTE24 zinc metallopeptidase STE24 1.261
NUP133 nucleoporin 133kDa 1.258
LMNB1 lamin B1 1.213
LMNB2 lamin B2 1.206
SUN3 Sad1 and UNC84 domain containing 3 1.204
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.202
KRAS Kirsten rat sarcoma viral oncogene homolog 1.201
POPDC2 popeye domain containing 2 1.193
ZFYVE16 zinc finger, FYVE domain containing 16 1.192
SMAD6 SMAD family member 6 1.177
WIF1 WNT inhibitory factor 1 1.175
TMEM201 transmembrane protein 201 1.171
MANEAL mannosidase, endo-alpha-like 1.16
PTH parathyroid hormone 1.153
MYORG myogenesis regulating glycosidase (putative) 1.143
RDH10 retinol dehydrogenase 10 (all-trans) 1.135
FERMT3 fermitin family member 3 1.128
BMPER BMP binding endothelial regulator 1.117
CCDC13 coiled-coil domain containing 13 1.112
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.098
SOST sclerostin 1.098
TMEM263 transmembrane protein 263 1.092
TMPO thymopoietin 1.082
SYNE3 spectrin repeat containing, nuclear envelope family member 3 1.08
SMAD5 SMAD family member 5 1.069
TOR1AIP1 torsin A interacting protein 1 1.064
PORCN porcupine homolog (Drosophila) 1.062
LMO7 LIM domain 7 1.056
RUNX2 runt-related transcription factor 2 1.048
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 1.046
TMEM209 transmembrane protein 209 1.043
BTBD6 BTB (POZ) domain containing 6 1.041
TMBIM4 transmembrane BAX inhibitor motif containing 4 1.04
NFYB nuclear transcription factor Y, beta 1.036
FOXH1 forkhead box H1 1.028
TMEM121 transmembrane protein 121 1.022
FBN1 fibrillin 1 1.02
RGPD2 RANBP2-like and GRIP domain containing 2 1.019
TMEM43 transmembrane protein 43 1.013
ALPL alkaline phosphatase, liver/bone/kidney 1.01
ICMT isoprenylcysteine carboxyl methyltransferase 1.008
RSPO4 R-spondin 4 1.005