| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.134974 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.132852 |
| VIM | vimentin | 0.127683 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.108052 |
| ATP13A3 | ATPase type 13A3 | 0.0947319 |
| PLAT | plasminogen activator, tissue | 0.0848991 |
| COL3A1 | collagen, type III, alpha 1 | 0.0793076 |
| PODXL | podocalyxin-like | 0.0702775 |
| APP | amyloid beta (A4) precursor protein | 0.0608022 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.060036 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.057228 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0555044 |
| FSTL1 | follistatin-like 1 | 0.0551122 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.053179 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0530034 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0514009 |
| CENPF | centromere protein F, 350/400kDa | 0.05084 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0501126 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0486657 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0468465 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0467565 |
| NAV2 | neuron navigator 2 | 0.0451846 |
| MCL1 | myeloid cell leukemia 1 | 0.0450909 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0432468 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0428504 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0426931 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.042458 |
| NEK7 | NIMA-related kinase 7 | 0.0422091 |
| CDH13 | cadherin 13 | 0.0416612 |
| TLE4 | transducin-like enhancer of split 4 | 0.0416561 |
| MB21D2 | Mab-21 domain containing 2 | 0.0410891 |
| SQSTM1 | sequestosome 1 | 0.0409777 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0406281 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0399287 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0388148 |
| INSIG1 | insulin induced gene 1 | 0.0371148 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0367014 |
| THBS2 | thrombospondin 2 | 0.0366894 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0364402 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0359435 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.035733 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0354898 |
| MKI67 | marker of proliferation Ki-67 | 0.0348982 |
| PTMA | prothymosin, alpha | 0.0345976 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0329605 |
| COL5A2 | collagen, type V, alpha 2 | 0.0329509 |
| OGA | O-GlcNAcase | 0.0328971 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0321522 |
| CENPE | centromere protein E, 312kDa | 0.031695 |
| CRY1 | cryptochrome circadian clock 1 | 0.0314146 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0312671 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0307857 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0303314 |
| ANLN | anillin, actin binding protein | 0.0302887 |
| GLIS3 | GLIS family zinc finger 3 | 0.0299019 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0297939 |
| RAB7A | RAB7A, member RAS oncogene family | 0.029617 |
| ERBIN | erbb2 interacting protein | 0.0296109 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0295973 |
| NUP98 | nucleoporin 98kDa | 0.0292915 |
| RND3 | Rho family GTPase 3 | 0.0291596 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0282616 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0278543 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0278542 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.027772 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0276968 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0272726 |
| ACTG1 | actin gamma 1 | 0.0270119 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0269874 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0269632 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0268614 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0268176 |
| NABP1 | nucleic acid binding protein 1 | 0.0267886 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0265592 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0265149 |
| FAT1 | FAT atypical cadherin 1 | 0.0259196 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0258701 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0257295 |
| KIF14 | kinesin family member 14 | 0.0249906 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0249033 |
| UBC | ubiquitin C | 0.0248884 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0248314 |
| TPX2 | TPX2, microtubule-associated | 0.0246281 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0243796 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.0242821 |
| HLA-B | major histocompatibility complex, class I, B | 0.0241659 |
| NMT2 | N-myristoyltransferase 2 | 0.0240538 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.023947 |
| WTAP | Wilms tumor 1 associated protein | 0.0239379 |
| FNIP1 | folliculin interacting protein 1 | 0.0238423 |
| DIAPH1 | diaphanous-related formin 1 | 0.0236659 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0236435 |
| FSTL5 | follistatin-like 5 | 0.0235429 |
| PCNX4 | pecanex 4 | 0.0233392 |
| JMJD1C | jumonji domain containing 1C | 0.0232395 |
| TENM3 | teneurin transmembrane protein 3 | 0.0230472 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0226785 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0226203 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0224687 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0224541 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.203614 |
| MT2A | metallothionein 2A | -0.152991 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.120166 |
| TMSB10 | thymosin beta 10 | -0.10927 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0939666 |
| MAP1B | microtubule-associated protein 1B | -0.0900528 |
| B2M | beta-2-microglobulin | -0.0833071 |
| AHNAK | AHNAK nucleoprotein | -0.0804306 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.074925 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0721183 |
| ZNF292 | zinc finger protein 292 | -0.0667403 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0625986 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0607784 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0605787 |
| MYADM | myeloid-associated differentiation marker | -0.0582952 |
| NAV1 | neuron navigator 1 | -0.05647 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0557033 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0556545 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.054445 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0543066 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0541051 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0536795 |
| TXNIP | thioredoxin interacting protein | -0.0534088 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0524474 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0488253 |
| LOXL2 | lysyl oxidase-like 2 | -0.0479508 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0476288 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0472659 |
| PRELID2 | PRELI domain containing 2 | -0.0466361 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0460528 |
| LDHA | lactate dehydrogenase A | -0.044526 |
| STC1 | stanniocalcin 1 | -0.0417331 |
| MT1X | metallothionein 1X | -0.0417091 |
| TAGLN2 | transgelin 2 | -0.0416415 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0408209 |
| SMIM44 | small integral membrane protein 44 | -0.0404368 |
| RTN4 | reticulon 4 | -0.0393089 |
| PFN1 | profilin 1 | -0.0385515 |
| GDF15 | growth differentiation factor 15 | -0.0383564 |
| MX2 | MX dynamin-like GTPase 2 | -0.0377698 |
| NDRG1 | N-myc downstream regulated 1 | -0.0374773 |
| RIGI | RNA sensor RIG-I | -0.0374381 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0373041 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0369015 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0368063 |
| CANX | calnexin | -0.0364043 |
| SMYD3 | SET and MYND domain containing 3 | -0.0363527 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0357437 |
| SEPTIN7 | septin 7 | -0.035651 |
| RRBP1 | ribosome binding protein 1 | -0.0353987 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.035141 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0347627 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0345318 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.034503 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0344682 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0342036 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0340674 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0338717 |
| S100A10 | S100 calcium binding protein A10 | -0.0336873 |
| SUCNR1 | succinate receptor 1 | -0.0336468 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0334547 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.033429 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0326714 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0324688 |
| LOX | lysyl oxidase | -0.0324371 |
| SRGN | serglycin | -0.032116 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0320791 |
| PHF21A | PHD finger protein 21A | -0.0312831 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0307903 |
| COL1A2 | collagen, type I, alpha 2 | -0.0307345 |
| TRAM2 | translocation associated membrane protein 2 | -0.0303453 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0299687 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0299505 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0298969 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0297122 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.029409 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0293959 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0292745 |
| CUX1 | cut-like homeobox 1 | -0.0292709 |
| NCOR2 | nuclear receptor corepressor 2 | -0.028944 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0282432 |
| BBX | bobby sox homolog (Drosophila) | -0.0281526 |
| VEGFA | vascular endothelial growth factor A | -0.0280268 |
| TPM4 | tropomyosin 4 | -0.0277966 |
| MYOF | myoferlin | -0.0277732 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.027628 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0276095 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0275401 |
| BSG | basigin (Ok blood group) | -0.0273942 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0272002 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0266829 |
| BPTF | bromodomain PHD finger transcription factor | -0.0265497 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0264932 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0264022 |
| FN1 | fibronectin 1 | -0.0263814 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0262924 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0259463 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0256685 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0254797 |
| FLNB | filamin B, beta | -0.0252683 |
