| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.113243 |
| RAB7A | RAB7A, member RAS oncogene family | 0.110945 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.101176 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0823383 |
| EGR1 | early growth response 1 | 0.0810426 |
| RASAL2 | RAS protein activator like 2 | 0.0803012 |
| HMGA2 | high mobility group AT-hook 2 | 0.0792785 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0718435 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0708592 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.065241 |
| ECT2 | epithelial cell transforming 2 | 0.0594287 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0543166 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0515786 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0427203 |
| HDAC9 | histone deacetylase 9 | 0.0427066 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0426781 |
| TMSB10 | thymosin beta 10 | 0.0415855 |
| H1-0 | H1.0 linker histone | 0.0412093 |
| JMJD1C | jumonji domain containing 1C | 0.0409204 |
| FNIP1 | folliculin interacting protein 1 | 0.0394422 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0371235 |
| CALR | calreticulin | 0.0365575 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0365076 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0362337 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0352197 |
| NAV3 | neuron navigator 3 | 0.0346342 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0346113 |
| KLF6 | Kruppel-like factor 6 | 0.0345875 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0338459 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0332226 |
| ADIPOR2 | adiponectin receptor 2 | 0.0331528 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0324629 |
| GCG | glucagon | 0.0323589 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0322366 |
| TUBA1B | tubulin, alpha 1b | 0.0320399 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.031302 |
| JUN | jun proto-oncogene | 0.0309152 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0308114 |
| NHSL1 | NHS-like 1 | 0.0303581 |
| BCHE | butyrylcholinesterase | 0.0302704 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0301682 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0297264 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0294183 |
| SETX | senataxin | 0.0294009 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0293569 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0293559 |
| EHBP1 | EH domain binding protein 1 | 0.0292385 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0280626 |
| CUX1 | cut-like homeobox 1 | 0.0279853 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0279585 |
| YAP1 | Yes-associated protein 1 | 0.0278183 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0276891 |
| ENO1 | enolase 1, (alpha) | 0.0274036 |
| PFN1 | profilin 1 | 0.0271987 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0267343 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0262809 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0257992 |
| ZNF207 | zinc finger protein 207 | 0.0251523 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0251137 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0250068 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0246926 |
| INTS6 | integrator complex subunit 6 | 0.0244423 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0241887 |
| CCNL1 | cyclin L1 | 0.0239791 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0237854 |
| GPHN | gephyrin | 0.0236708 |
| KIF18A | kinesin family member 18A | 0.0232743 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0230796 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0230429 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.0229533 |
| TTC27 | tetratricopeptide repeat domain 27 | 0.0221935 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0219803 |
| PCDH7 | protocadherin 7 | 0.021856 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0218437 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.021834 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0216011 |
| KIF18B | kinesin family member 18B | 0.0215516 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0212057 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0208744 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0207622 |
| MYPN | myopalladin | 0.0204766 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0204617 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0203796 |
| PTMA | prothymosin, alpha | 0.0202113 |
| CRY1 | cryptochrome circadian clock 1 | 0.0202036 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0200918 |
| MED13 | mediator complex subunit 13 | 0.020084 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0198012 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0195439 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0193346 |
| PER1 | period circadian clock 1 | 0.0192102 |
| ZNF804A | zinc finger protein 804A | 0.0189347 |
| MEMO1 | mediator of cell motility 1 | 0.0188798 |
| ATL2 | atlastin GTPase 2 | 0.0186879 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.018622 |
| ACTG1 | actin gamma 1 | 0.0183761 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0182097 |
| POTEF | POTE ankyrin domain family, member F | 0.0179337 |
| NLGN1 | neuroligin 1 | 0.0179135 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0178621 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.208035 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.126379 |
| RPS2 | ribosomal protein S2 | -0.113248 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0807421 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0759669 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0721161 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0659822 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0643691 |
| ATP11A | ATPase, class VI, type 11A | -0.058566 |
| TENM3 | teneurin transmembrane protein 3 | -0.0571801 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0568837 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0530912 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0510382 |
| YEATS2 | YEATS domain containing 2 | -0.0494404 |
| ZNF292 | zinc finger protein 292 | -0.0479456 |
| EXOC6B | exocyst complex component 6B | -0.0475929 |
| KIF5B | kinesin family member 5B | -0.0462724 |
| RPS12 | ribosomal protein S12 | -0.0459118 |
| CPOX | coproporphyrinogen oxidase | -0.0456429 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0455633 |
| EDN1 | endothelin 1 | -0.0442803 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0442486 |
| RPS3 | ribosomal protein S3 | -0.0435521 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0413441 |
| RPL26 | ribosomal protein L26 | -0.041101 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0405327 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0404255 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0402647 |
| OGA | O-GlcNAcase | -0.0400874 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0398103 |
| RPL11 | ribosomal protein L11 | -0.0392712 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0388064 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0383767 |
| DST | dystonin | -0.0382592 |
| TXNRD1 | thioredoxin reductase 1 | -0.0374647 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0370602 |
| TNPO1 | transportin 1 | -0.0364497 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0361417 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0360054 |
| SET | SET nuclear proto-oncogene | -0.0358792 |
| XPO1 | exportin 1 | -0.0358153 |
| TMEM41B | transmembrane protein 41B | -0.03572 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0357003 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.0352518 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0352433 |
| GOLGA4 | golgin A4 | -0.0349475 |
| NEK7 | NIMA-related kinase 7 | -0.0347967 |
| RPL19 | ribosomal protein L19 | -0.0346773 |
| RAD51B | RAD51 paralog B | -0.0338803 |
| RPS27A | ribosomal protein S27a | -0.0338801 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.033492 |
| FTL | ferritin, light polypeptide | -0.0334714 |
| YBX3 | Y box binding protein 3 | -0.0325859 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0325046 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0323073 |
| SMYD3 | SET and MYND domain containing 3 | -0.0323073 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.031952 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0316718 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.031193 |
| RPL38 | ribosomal protein L38 | -0.0309129 |
| IL6ST | interleukin 6 signal transducer | -0.030879 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0304593 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0303786 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0302739 |
| RPL7 | ribosomal protein L7 | -0.0297607 |
| NEBL | nebulette | -0.0295338 |
| RPL23 | ribosomal protein L23 | -0.0294755 |
| BBX | bobby sox homolog (Drosophila) | -0.0293812 |
| PRKCI | protein kinase C, iota | -0.0292804 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.028892 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0288372 |
| LMO7 | LIM domain 7 | -0.0285579 |
| AHNAK | AHNAK nucleoprotein | -0.0283482 |
| MED13L | mediator complex subunit 13-like | -0.02833 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0279647 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0278167 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0278147 |
| RPL12 | ribosomal protein L12 | -0.0277045 |
| MPG | N-methylpurine-DNA glycosylase | -0.0276933 |
| PHF3 | PHD finger protein 3 | -0.0275977 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.027435 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0272601 |
| WWOX | WW domain containing oxidoreductase | -0.0269185 |
| CLTC | clathrin, heavy chain (Hc) | -0.0269088 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0264462 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0263837 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0263048 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0261505 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0258516 |
| RPL37 | ribosomal protein L37 | -0.0257415 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0254626 |
| SERINC1 | serine incorporator 1 | -0.025204 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0251538 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0248565 |
| DSG2 | desmoglein 2 | -0.0246406 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0245243 |
| CDK19 | cyclin-dependent kinase 19 | -0.0243882 |
| PCM1 | pericentriolar material 1 | -0.0243337 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0241463 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0240361 |
