| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.0492101 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0481458 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.045874 |
| LMTK2 | lemur tyrosine kinase 2 | 0.045206 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.039799 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0386425 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.036876 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.036582 |
| NEK7 | NIMA-related kinase 7 | 0.036285 |
| SMAD3 | SMAD family member 3 | 0.0362348 |
| SQSTM1 | sequestosome 1 | 0.0351058 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0345636 |
| ITGA6 | integrin, alpha 6 | 0.0339499 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0336718 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.032002 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0314436 |
| FOSL1 | FOS-like antigen 1 | 0.0313439 |
| H1-0 | H1.0 linker histone | 0.0294113 |
| VCAN | versican | 0.0290809 |
| MYOF | myoferlin | 0.027301 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0267629 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0263646 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.026174 |
| TOP1 | topoisomerase (DNA) I | 0.0260726 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0255878 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0248312 |
| FAT1 | FAT atypical cadherin 1 | 0.0245665 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0238261 |
| VCL | vinculin | 0.0238027 |
| NPTN | neuroplastin | 0.0234211 |
| ITGB4 | integrin, beta 4 | 0.0234039 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0224421 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0217781 |
| ANXA11 | annexin A11 | 0.0215228 |
| SLTM | SAFB-like, transcription modulator | 0.0210483 |
| RTN4 | reticulon 4 | 0.0209698 |
| ARRDC3 | arrestin domain containing 3 | 0.020943 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.020557 |
| RIN2 | Ras and Rab interactor 2 | 0.020226 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0197487 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0197124 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.019033 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0188876 |
| XPO1 | exportin 1 | 0.0188083 |
| EREG | epiregulin | 0.0187949 |
| SERTAD2 | SERTA domain containing 2 | 0.0187643 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0187357 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0186026 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0183196 |
| RHEB | Ras homolog enriched in brain | 0.0181321 |
| PTEN | phosphatase and tensin homolog | 0.0180555 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0180322 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.017646 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0176307 |
| RLF | rearranged L-myc fusion | 0.0174957 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0173093 |
| WWC1 | WW and C2 domain containing 1 | 0.0171112 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0169314 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0168714 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0168547 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0165876 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0164396 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0164378 |
| ZFP36 | ZFP36 ring finger protein | 0.0163943 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0161552 |
| CAB39 | calcium binding protein 39 | 0.0160869 |
| ITGAV | integrin, alpha V | 0.0160629 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0160459 |
| CDCP1 | CUB domain containing protein 1 | 0.0159769 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0158684 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0158339 |
| CCNL1 | cyclin L1 | 0.0155891 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0154899 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0152354 |
| RPS2 | ribosomal protein S2 | 0.0147675 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 0.0144491 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0144488 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0142765 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0142724 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0142223 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0139981 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0139613 |
| OLA1 | Obg-like ATPase 1 | 0.013853 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0138303 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0137732 |
| CRY1 | cryptochrome circadian clock 1 | 0.0136944 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0134637 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0133829 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0133742 |
| ZFR | zinc finger RNA binding protein | 0.0133313 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0132933 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0131809 |
| FOXO1 | forkhead box O1 | 0.012989 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0127933 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.012773 |
| IPO7 | importin 7 | 0.0127433 |
| AZIN1 | antizyme inhibitor 1 | 0.0126575 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0126393 |
| YAP1 | Yes-associated protein 1 | 0.0126239 |
| JAG1 | jagged 1 | 0.0124884 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.182009 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.161954 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.159709 |
| FLNB | filamin B, beta | -0.101287 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0996374 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0947359 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0937132 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0912277 |
| TXNIP | thioredoxin interacting protein | -0.0910598 |
| TMSB10 | thymosin beta 10 | -0.0895094 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0883656 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.085402 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0778754 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0775841 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0743449 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0729182 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0726335 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0715955 |
| KLK10 | kallikrein-related peptidase 10 | -0.0689067 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0659924 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0647912 |
| MXD1 | MAX dimerization protein 1 | -0.0643775 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0636866 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0599528 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.059742 |
| PMM2 | phosphomannomutase 2 | -0.0597221 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0595128 |
| TRRAP | transformation/transcription domain-associated protein | -0.0577547 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0572356 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0568971 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0562915 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0546195 |
| PARD3 | par-3 family cell polarity regulator | -0.0523846 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0519225 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0512857 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0502984 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0499133 |
| CDK13 | cyclin-dependent kinase 13 | -0.0493304 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0487805 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0487073 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0485573 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0479409 |
| NPSR1 | neuropeptide S receptor 1 | -0.0477688 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0473676 |
| PTMA | prothymosin, alpha | -0.0471931 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0470413 |
| DIAPH2 | diaphanous-related formin 2 | -0.0467721 |
| HDLBP | high density lipoprotein binding protein | -0.0461154 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0455663 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0449846 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0440718 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0433945 |
| VIM | vimentin | -0.043207 |
| COPA | coatomer protein complex, subunit alpha | -0.04298 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.042338 |
| CLMP | CXADR-like membrane protein | -0.0423084 |
| PERP | PERP, TP53 apoptosis effector | -0.0420734 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.041874 |
| MORF4L2 | mortality factor 4 like 2 | -0.0414547 |
| DIAPH1 | diaphanous-related formin 1 | -0.0403494 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0403443 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0402494 |
| SVIL | supervillin | -0.0400711 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0395959 |
| ARF4 | ADP-ribosylation factor 4 | -0.0393786 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0390183 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0389551 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0388044 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0387233 |
| GOLGA4 | golgin A4 | -0.0384356 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0380399 |
| RIOK3 | RIO kinase 3 | -0.0380195 |
| EGFR | epidermal growth factor receptor | -0.0377061 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.03755 |
| S100A11 | S100 calcium binding protein A11 | -0.0374676 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0374534 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0373359 |
| FBXO11 | F-box protein 11 | -0.0372406 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0371516 |
| LMO7 | LIM domain 7 | -0.0370129 |
| EZR | ezrin | -0.0368002 |
| MSN | moesin | -0.0362429 |
| RASAL2 | RAS protein activator like 2 | -0.0359037 |
| NDRG1 | N-myc downstream regulated 1 | -0.0358529 |
| SRP54 | signal recognition particle 54kDa | -0.035811 |
| CALU | calumenin | -0.035504 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0350581 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0350557 |
| EFNA5 | ephrin-A5 | -0.03469 |
| PGK1 | phosphoglycerate kinase 1 | -0.0345234 |
| HDAC9 | histone deacetylase 9 | -0.0344801 |
| GOLGB1 | golgin B1 | -0.0344324 |
| SP100 | SP100 nuclear antigen | -0.0340904 |
| TAOK3 | TAO kinase 3 | -0.0336573 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0332986 |
| COG5 | component of oligomeric golgi complex 5 | -0.033258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0330622 |
| ANXA2 | annexin A2 | -0.0328975 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0328507 |
| MCL1 | myeloid cell leukemia 1 | -0.0327513 |
