| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0779205 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0627062 |
| MCL1 | myeloid cell leukemia 1 | 0.0456003 |
| CCNL1 | cyclin L1 | 0.045111 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0444022 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0385159 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0384168 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.038408 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0375344 |
| SMAD3 | SMAD family member 3 | 0.033683 |
| VMP1 | vacuole membrane protein 1 | 0.0318652 |
| TAOK3 | TAO kinase 3 | 0.0318465 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0317975 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0310257 |
| MYO10 | myosin X | 0.0309648 |
| WWC2 | WW and C2 domain containing 2 | 0.0305789 |
| WWC1 | WW and C2 domain containing 1 | 0.0290215 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0268219 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0266787 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0249871 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0245339 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0244091 |
| ETNK1 | ethanolamine kinase 1 | 0.0243963 |
| SGMS2 | sphingomyelin synthase 2 | 0.023567 |
| UBAP1 | ubiquitin associated protein 1 | 0.0234563 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.02343 |
| ATP13A3 | ATPase type 13A3 | 0.0230754 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0219105 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 0.0217663 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.021649 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0215678 |
| ATF3 | activating transcription factor 3 | 0.0215496 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0210158 |
| SLMAP | sarcolemma associated protein | 0.0209013 |
| NPTN | neuroplastin | 0.0205391 |
| FDPS | farnesyl diphosphate synthase | 0.0204634 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0203047 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0202244 |
| WDR26 | WD repeat domain 26 | 0.0198707 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0195374 |
| EGR1 | early growth response 1 | 0.0192037 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.019045 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0190091 |
| LATS2 | large tumor suppressor kinase 2 | 0.0188259 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0187057 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0184015 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0179692 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0178007 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0176278 |
| CRY1 | cryptochrome circadian clock 1 | 0.0171773 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0170621 |
| CD83 | CD83 molecule | 0.0167622 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0167563 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0167109 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0164649 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0162422 |
| EZR | ezrin | 0.0161394 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0161183 |
| CADM1 | cell adhesion molecule 1 | 0.0159621 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.0159607 |
| LEMD3 | LEM domain containing 3 | 0.0159553 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0159434 |
| YTHDC1 | YTH domain containing 1 | 0.0159398 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0159082 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0158804 |
| CEP95 | centrosomal protein 95kDa | 0.0157419 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.015625 |
| LRRC8B | leucine rich repeat containing 8 family, member B | 0.0155544 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0153761 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0151432 |
| SIRT1 | sirtuin 1 | 0.0150679 |
| SIK3 | SIK family kinase 3 | 0.0150046 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0149142 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0147593 |
| TUFT1 | tuftelin 1 | 0.0147531 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0146515 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0146081 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0145901 |
| TSC22D2 | TSC22 domain family, member 2 | 0.014549 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0145401 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0145191 |
| AZIN1 | antizyme inhibitor 1 | 0.0143706 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0143562 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0142709 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.014223 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0141681 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0141591 |
| S100A8 | S100 calcium binding protein A8 | 0.0139969 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0139596 |
| STK17A | serine/threonine kinase 17a | 0.0138227 |
| CNST | consortin, connexin sorting protein | 0.0137542 |
| WAC | WW domain containing adaptor with coiled-coil | 0.013696 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0136391 |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.0136361 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0135811 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0135472 |
| PER1 | period circadian clock 1 | 0.0135351 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0134937 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0133886 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0133264 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.20589 |
| RPL19 | ribosomal protein L19 | -0.179963 |
| RPL23 | ribosomal protein L23 | -0.167403 |
| CLTC | clathrin, heavy chain (Hc) | -0.0846197 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0822775 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0768766 |
| ASPH | aspartate beta-hydroxylase | -0.0671754 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0653927 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.064302 |
| TMEM123 | transmembrane protein 123 | -0.0629793 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0579786 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0541534 |
| ENO1 | enolase 1, (alpha) | -0.0515132 |
| ACTG1 | actin gamma 1 | -0.0501138 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0491353 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0488421 |
| DSPP | dentin sialophosphoprotein | -0.0449172 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0444494 |
| CEP250 | centrosomal protein 250kDa | -0.0439147 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0423998 |
| CANX | calnexin | -0.0410075 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0403552 |
| LDHA | lactate dehydrogenase A | -0.0396002 |
| VCP | valosin containing protein | -0.0393937 |
| MT2A | metallothionein 2A | -0.0381179 |
| LASP1 | LIM and SH3 protein 1 | -0.0380509 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0377 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0365429 |
| PGK1 | phosphoglycerate kinase 1 | -0.0353206 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0352857 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0349523 |
| TMSB4X | thymosin beta 4, X-linked | -0.0346635 |
| AHNAK | AHNAK nucleoprotein | -0.0344456 |
| ZNF292 | zinc finger protein 292 | -0.0344333 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0338858 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0324305 |
| ENAH | enabled homolog (Drosophila) | -0.0323129 |
| KRT18 | keratin 18, type I | -0.0320362 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0318383 |
| RPL12 | ribosomal protein L12 | -0.0313778 |
| GOLGB1 | golgin B1 | -0.0309686 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | -0.0304033 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0300011 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0294772 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0294072 |
| PFDN4 | prefoldin subunit 4 | -0.0289558 |
| TPD52 | tumor protein D52 | -0.0288278 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0285763 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0285604 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0282839 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0279071 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0278729 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0278086 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0276963 |
| CCND1 | cyclin D1 | -0.0276778 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0275194 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0270795 |
| EXOC4 | exocyst complex component 4 | -0.0269671 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0269181 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0269172 |
| NDRG1 | N-myc downstream regulated 1 | -0.0267836 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0267684 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0265669 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -0.0265427 |
| ARF1 | ADP-ribosylation factor 1 | -0.026263 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0260339 |
| KRT8 | keratin 8, type II | -0.0260257 |
| INHBA | inhibin, beta A | -0.0259428 |
| RAI1 | retinoic acid induced 1 | -0.0257871 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0254662 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0254462 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0254214 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0253092 |
| B2M | beta-2-microglobulin | -0.0252142 |
| SET | SET nuclear proto-oncogene | -0.0250383 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0250081 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0249301 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0244017 |
| RAD51B | RAD51 paralog B | -0.0243958 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.024374 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0242919 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0242826 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0237536 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0237208 |
| PTMA | prothymosin, alpha | -0.0236762 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0234147 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0233625 |
| BPTF | bromodomain PHD finger transcription factor | -0.0232025 |
| BBX | bobby sox homolog (Drosophila) | -0.023199 |
| RRBP1 | ribosome binding protein 1 | -0.0230837 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.023005 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0229993 |
| SP100 | SP100 nuclear antigen | -0.0229502 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.0228659 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0226343 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0226241 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0221963 |
| PRELID2 | PRELI domain containing 2 | -0.022145 |
| DENND1A | DENN/MADD domain containing 1A | -0.0221351 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0220694 |
