| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.104186 |
| JMJD1C | jumonji domain containing 1C | 0.0643482 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0544179 |
| COL5A2 | collagen, type V, alpha 2 | 0.0537739 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0473474 |
| PTK2 | protein tyrosine kinase 2 | 0.0466656 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0448675 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0433955 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0429858 |
| RBM25 | RNA binding motif protein 25 | 0.0422525 |
| MED13 | mediator complex subunit 13 | 0.0421232 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0416238 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0412355 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0407732 |
| QKI | QKI, KH domain containing, RNA binding | 0.040613 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0400852 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0384415 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0376974 |
| RPS6 | ribosomal protein S6 | 0.03731 |
| CENPF | centromere protein F, 350/400kDa | 0.0368654 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0366735 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0360664 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0348576 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0343926 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0339832 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0338472 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0335466 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0332838 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.032224 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0307968 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0305346 |
| MED13L | mediator complex subunit 13-like | 0.0303065 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.030154 |
| SET | SET nuclear proto-oncogene | 0.0301117 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0296939 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0296659 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0295775 |
| RPS21 | ribosomal protein S21 | 0.0294893 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0293234 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0290907 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0289587 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0287989 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0287193 |
| RPL37A | ribosomal protein L37a | 0.0285545 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.028468 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0281877 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0281094 |
| PCM1 | pericentriolar material 1 | 0.0278125 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0276949 |
| RPL9 | ribosomal protein L9 | 0.0273414 |
| SRPK2 | SRSF protein kinase 2 | 0.0272471 |
| RBM33 | RNA binding motif protein 33 | 0.0268127 |
| LATS2 | large tumor suppressor kinase 2 | 0.02654 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.026279 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0261882 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.025862 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0257704 |
| PHIP | pleckstrin homology domain interacting protein | 0.0257265 |
| IPO7 | importin 7 | 0.0257205 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0256039 |
| ZNF638 | zinc finger protein 638 | 0.0253787 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0252117 |
| PNN | pinin, desmosome associated protein | 0.0249048 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0249013 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0247735 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0247682 |
| DIAPH1 | diaphanous-related formin 1 | 0.0247641 |
| PCBP2 | poly(rC) binding protein 2 | 0.0246493 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.024627 |
| RPS12 | ribosomal protein S12 | 0.0245996 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0241903 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0240414 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0239899 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0237968 |
| USP34 | ubiquitin specific peptidase 34 | 0.0237726 |
| USP47 | ubiquitin specific peptidase 47 | 0.0236379 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0236326 |
| SETD5 | SET domain containing 5 | 0.0233767 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0233264 |
| PDS5B | PDS5 cohesin associated factor B | 0.0233223 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0232548 |
| BRD4 | bromodomain containing 4 | 0.022856 |
| RPL11 | ribosomal protein L11 | 0.0228513 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0228176 |
| ARMH4 | armadillo like helical domain containing 4 | 0.0227969 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0227896 |
| WDR43 | WD repeat domain 43 | 0.0227534 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0226851 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0226491 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0226349 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0226263 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0225214 |
| SMC5 | structural maintenance of chromosomes 5 | 0.022428 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0223156 |
| RPLP2 | ribosomal protein, large, P2 | 0.0222569 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0221877 |
| PAPOLA | poly(A) polymerase alpha | 0.0221809 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0219987 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0219701 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0219218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104742 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0963236 |
| SMYD3 | SET and MYND domain containing 3 | -0.0529251 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0504479 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0377119 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0356639 |
| LDHA | lactate dehydrogenase A | -0.0333635 |
| NEBL | nebulette | -0.0321405 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0314629 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0303694 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0298567 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0297935 |
| CADM2 | cell adhesion molecule 2 | -0.0294994 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0292737 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0279024 |
| PGK1 | phosphoglycerate kinase 1 | -0.0271258 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259088 |
| TENM3 | teneurin transmembrane protein 3 | -0.0257041 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0255617 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.025147 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0245985 |
| SBF2 | SET binding factor 2 | -0.0241119 |
| NGLY1 | N-glycanase 1 | -0.0237678 |
| ARFGEF3 | ARFGEF family member 3 | -0.0233247 |
| WDR45B | WD repeat domain 45B | -0.022306 |
| AUTS2 | autism susceptibility candidate 2 | -0.021996 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0217917 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0217576 |
| H1-0 | H1.0 linker histone | -0.0216443 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0214152 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0210159 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0206352 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0205794 |
| EGR1 | early growth response 1 | -0.0204498 |
| ZNF217 | zinc finger protein 217 | -0.0203782 |
| RRBP1 | ribosome binding protein 1 | -0.0197834 |
| ZNF33A | zinc finger protein 33A | -0.0195834 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0195706 |
| RAD51B | RAD51 paralog B | -0.0190536 |
| TBC1D32 | TBC1 domain family, member 32 | -0.018845 |
| DST | dystonin | -0.0184398 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0183861 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0178648 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0177363 |
| TPD52 | tumor protein D52 | -0.0175008 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0174831 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0173815 |
| CABIN1 | calcineurin binding protein 1 | -0.0173354 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0170382 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0168028 |
| INSIG2 | insulin induced gene 2 | -0.0164828 |
| RPL4 | ribosomal protein L4 | -0.0162906 |
| MAPT | microtubule-associated protein tau | -0.0161165 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0160593 |
| HELZ | helicase with zinc finger | -0.0160184 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0159217 |
| S100A10 | S100 calcium binding protein A10 | -0.0155733 |
| PCDH11X | protocadherin 11 X-linked | -0.0155031 |
| CCDC47 | coiled-coil domain containing 47 | -0.0152196 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0150584 |
| HMGB2 | high mobility group box 2 | -0.0148008 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0147702 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0147675 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.014572 |
| CAVIN1 | caveolae associated protein 1 | -0.0145344 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0145157 |
| GYS1 | glycogen synthase 1 (muscle) | -0.014461 |
| HIP1 | huntingtin interacting protein 1 | -0.0142778 |
| TUBB | tubulin, beta class I | -0.0142356 |
| TMEM14B | transmembrane protein 14B | -0.0141233 |
| TMEM123 | transmembrane protein 123 | -0.0141193 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0140538 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0139703 |
| FAM162A | family with sequence similarity 162, member A | -0.0139534 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0138643 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0137456 |
| ZNF770 | zinc finger protein 770 | -0.0137433 |
| SNX14 | sorting nexin 14 | -0.0136376 |
| CANX | calnexin | -0.0133392 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0133312 |
| ASPH | aspartate beta-hydroxylase | -0.0132752 |
| RNF150 | ring finger protein 150 | -0.013167 |
| RIGI | RNA sensor RIG-I | -0.0130901 |
| MXI1 | MAX interactor 1, dimerization protein | -0.013078 |
| ATRN | attractin | -0.0129358 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0127937 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0127671 |
| LPIN2 | lipin 2 | -0.012552 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0123885 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.0123685 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0122988 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0121939 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.0120951 |
| PRELID2 | PRELI domain containing 2 | -0.0120409 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0120363 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0118122 |
| FOXO3 | forkhead box O3 | -0.0117607 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0117389 |
| RORA | RAR-related orphan receptor A | -0.0117031 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0115905 |
