| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.107365 |
| CDC73 | cell division cycle 73 | 0.0917697 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0859697 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0824533 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0721634 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0655606 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0623662 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0560843 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0549214 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0543353 |
| VMP1 | vacuole membrane protein 1 | 0.052134 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0504944 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0501618 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.048232 |
| RNF145 | ring finger protein 145 | 0.0477774 |
| HELZ | helicase with zinc finger | 0.0465478 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0449104 |
| RBM33 | RNA binding motif protein 33 | 0.044793 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0436252 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0435028 |
| TXNIP | thioredoxin interacting protein | 0.0434636 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0424548 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0422344 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0420787 |
| SRPK2 | SRSF protein kinase 2 | 0.0420227 |
| NUP58 | nucleoporin 58 | 0.0416064 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.04154 |
| RCOR1 | REST corepressor 1 | 0.0413811 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0412585 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0412425 |
| MED13L | mediator complex subunit 13-like | 0.0398103 |
| COPA | coatomer protein complex, subunit alpha | 0.0392878 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0386848 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0376016 |
| SPAG9 | sperm associated antigen 9 | 0.0369976 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0369672 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0365758 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0357956 |
| AHR | aryl hydrocarbon receptor | 0.0356441 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0355989 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0355456 |
| CCNL1 | cyclin L1 | 0.035075 |
| EGR1 | early growth response 1 | 0.0348044 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0338572 |
| MCL1 | myeloid cell leukemia 1 | 0.0337689 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0327758 |
| APP | amyloid beta (A4) precursor protein | 0.0327617 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.03251 |
| NBAS | neuroblastoma amplified sequence | 0.0324203 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0323688 |
| ERBIN | erbb2 interacting protein | 0.0317456 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0316604 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0313038 |
| RTN4 | reticulon 4 | 0.0311704 |
| SEM1 | SEM1 26S proteasome subunit | 0.0308281 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0307445 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0305748 |
| TOP1 | topoisomerase (DNA) I | 0.0305015 |
| SON | SON DNA binding protein | 0.0303654 |
| CUL3 | cullin 3 | 0.0303245 |
| RHEB | Ras homolog enriched in brain | 0.0297409 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0294921 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.029414 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0292433 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0289444 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0288626 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0283957 |
| DCT | dopachrome tautomerase | 0.0281983 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0280603 |
| TMEM117 | transmembrane protein 117 | 0.0280111 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0280017 |
| HDAC9 | histone deacetylase 9 | 0.0279453 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0278955 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0277678 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0277629 |
| MRTFA | myocardin related transcription factor A | 0.027657 |
| PI15 | peptidase inhibitor 15 | 0.0275898 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0273803 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0273775 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0272554 |
| RBM39 | RNA binding motif protein 39 | 0.0271968 |
| CYTH3 | cytohesin 3 | 0.0271417 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0270764 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.026828 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0267505 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0264532 |
| ENTHD1 | ENTH domain containing 1 | 0.0258615 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0257101 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0255171 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0254614 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0253975 |
| QKI | QKI, KH domain containing, RNA binding | 0.0252394 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0252202 |
| MTPN | myotrophin | 0.025128 |
| ATF6 | activating transcription factor 6 | 0.0250325 |
| ETNK1 | ethanolamine kinase 1 | 0.0249392 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0249112 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0247743 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0247377 |
| ATP13A3 | ATPase type 13A3 | 0.0246498 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | -0.104492 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0786768 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0759328 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0730026 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0663168 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0635236 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0529187 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0523823 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0514035 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0503375 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0497679 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0484964 |
| ASPH | aspartate beta-hydroxylase | -0.0472756 |
| PDE10A | phosphodiesterase 10A | -0.0458751 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0451235 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0447787 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0440024 |
| CTTNBP2 | cortactin binding protein 2 | -0.0416725 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0399948 |
| OXR1 | oxidation resistance 1 | -0.0391877 |
| VIM | vimentin | -0.0365995 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0364219 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0362209 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0349715 |
| GPC6 | glypican 6 | -0.0346176 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0345366 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0332564 |
| NAV3 | neuron navigator 3 | -0.0331373 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0324347 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0315677 |
| SCFD2 | sec1 family domain containing 2 | -0.0312513 |
| NLGN1 | neuroligin 1 | -0.0311959 |
| RRBP1 | ribosome binding protein 1 | -0.0298776 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0296141 |
| PRELID2 | PRELI domain containing 2 | -0.029141 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.028502 |
| NDRG1 | N-myc downstream regulated 1 | -0.0284768 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.027792 |
| IER3 | immediate early response 3 | -0.027703 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0276897 |
| ACTG1 | actin gamma 1 | -0.0269298 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0266442 |
| FRMD4A | FERM domain containing 4A | -0.026507 |
| S100A6 | S100 calcium binding protein A6 | -0.0262319 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.026221 |
| PARVB | parvin, beta | -0.0253568 |
| CAVIN1 | caveolae associated protein 1 | -0.0251012 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0250887 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0247183 |
| CD109 | CD109 molecule | -0.0246713 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0244795 |
| EHBP1 | EH domain binding protein 1 | -0.02358 |
| AHNAK | AHNAK nucleoprotein | -0.0235468 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0232564 |
| TNNC1 | troponin C type 1 (slow) | -0.0230631 |
| NPC1 | Niemann-Pick disease, type C1 | -0.023054 |
| LMNA | lamin A/C | -0.0229899 |
| NAV1 | neuron navigator 1 | -0.0227687 |
| GSN | gelsolin | -0.0225216 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0224761 |
| TAC4 | tachykinin 4 (hemokinin) | -0.022203 |
| SDC2 | syndecan 2 | -0.0220503 |
| NRCAM | neuronal cell adhesion molecule | -0.0218461 |
| PGK1 | phosphoglycerate kinase 1 | -0.0211063 |
| RASA3 | RAS p21 protein activator 3 | -0.0203894 |
| MTDH | metadherin | -0.0201739 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0200485 |
| A2M | alpha-2-macroglobulin | -0.0198502 |
| TMEM123 | transmembrane protein 123 | -0.0197683 |
| TPM4 | tropomyosin 4 | -0.0196964 |
| NPR2 | natriuretic peptide receptor 2 | -0.0194997 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0191352 |
| SEPTIN9 | septin 9 | -0.0190514 |
| PLIN2 | perilipin 2 | -0.0190303 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0184927 |
| TRIM2 | tripartite motif containing 2 | -0.018212 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0180491 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0179381 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0176861 |
| STXBP1 | syntaxin binding protein 1 | -0.0175575 |
| RPLP1 | ribosomal protein, large, P1 | -0.0175087 |
| ENO1 | enolase 1, (alpha) | -0.017244 |
| MYO1E | myosin IE | -0.0172323 |
| EXOC4 | exocyst complex component 4 | -0.0172102 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0170053 |
| S100A10 | S100 calcium binding protein A10 | -0.0170036 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0169717 |
| SSH1 | slingshot protein phosphatase 1 | -0.0169279 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0161486 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0160589 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0159181 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0158429 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -0.0156816 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.0156352 |
| NRP2 | neuropilin 2 | -0.0156147 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0155369 |
| LDHA | lactate dehydrogenase A | -0.0154121 |
| GNAS | GNAS complex locus | -0.0152777 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0152586 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0151945 |
