| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0730632 |
| TSC22D2 | TSC22 domain family, member 2 | 0.06018 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0551439 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0534488 |
| TXNIP | thioredoxin interacting protein | 0.0506341 |
| MT2A | metallothionein 2A | 0.0491666 |
| MCL1 | myeloid cell leukemia 1 | 0.047708 |
| CCNL1 | cyclin L1 | 0.0451486 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0354831 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0345265 |
| BRD2 | bromodomain containing 2 | 0.0331295 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.033035 |
| TFRC | transferrin receptor | 0.0319469 |
| ARRDC3 | arrestin domain containing 3 | 0.0310255 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0310149 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0299283 |
| TOP1 | topoisomerase (DNA) I | 0.028896 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0282574 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0280064 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0276186 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0269489 |
| GPHN | gephyrin | 0.0256692 |
| SMAD3 | SMAD family member 3 | 0.0255385 |
| RBM25 | RNA binding motif protein 25 | 0.0253561 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0247739 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0245821 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0241695 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0241168 |
| FNIP1 | folliculin interacting protein 1 | 0.0239716 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0238022 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0233683 |
| ATP13A3 | ATPase type 13A3 | 0.0230546 |
| RBM39 | RNA binding motif protein 39 | 0.0230139 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0228168 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0219312 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0218765 |
| CD83 | CD83 molecule | 0.0212 |
| MKI67 | marker of proliferation Ki-67 | 0.0204075 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0200531 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0199661 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.019505 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0192334 |
| YTHDC1 | YTH domain containing 1 | 0.0190861 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0190273 |
| NUP58 | nucleoporin 58 | 0.0188347 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0184244 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0182924 |
| FOSL1 | FOS-like antigen 1 | 0.0182538 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0181695 |
| SIK3 | SIK family kinase 3 | 0.0179315 |
| CENPF | centromere protein F, 350/400kDa | 0.0177174 |
| MED13 | mediator complex subunit 13 | 0.0176976 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0176445 |
| THBS1 | thrombospondin 1 | 0.0175599 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0175266 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.017507 |
| PCBP2 | poly(rC) binding protein 2 | 0.0174726 |
| MATR3 | matrin 3 | 0.0174591 |
| SON | SON DNA binding protein | 0.0174578 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0170909 |
| EP300 | E1A binding protein p300 | 0.0170043 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0169936 |
| MT1X | metallothionein 1X | 0.0169564 |
| PEG10 | paternally expressed 10 | 0.0168233 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.01658 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0165467 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0161525 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0160465 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0157288 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.015651 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0155138 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0153721 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.015143 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0151404 |
| SIRT1 | sirtuin 1 | 0.0151261 |
| SQSTM1 | sequestosome 1 | 0.0149613 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0146518 |
| NUP153 | nucleoporin 153kDa | 0.0146303 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0144953 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0143397 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0143213 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0142043 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.014146 |
| CAPRIN2 | caprin family member 2 | 0.0140347 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0139626 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0134218 |
| ATF3 | activating transcription factor 3 | 0.0133523 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0132592 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0131492 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0130571 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0129528 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0129499 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0129046 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0128947 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0128311 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.012674 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0126001 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0125818 |
| NXF1 | nuclear RNA export factor 1 | 0.0125032 |
| RLF | rearranged L-myc fusion | 0.012448 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.155626 |
| TMSB10 | thymosin beta 10 | -0.13283 |
| MMP7 | matrix metallopeptidase 7 | -0.113793 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.109896 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0950986 |
| PTMA | prothymosin, alpha | -0.0932259 |
| S100A6 | S100 calcium binding protein A6 | -0.078942 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0736944 |
| CP | ceruloplasmin (ferroxidase) | -0.0712067 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.071043 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0669075 |
| LMO7 | LIM domain 7 | -0.0661227 |
| APOL1 | apolipoprotein L, 1 | -0.0649136 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0646948 |
| B2M | beta-2-microglobulin | -0.0615682 |
| KRT19 | keratin 19, type I | -0.0603884 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0587987 |
| HLA-B | major histocompatibility complex, class I, B | -0.0582418 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0564563 |
| TMSB4X | thymosin beta 4, X-linked | -0.0523688 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0514157 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0503891 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0499426 |
| PGK1 | phosphoglycerate kinase 1 | -0.0497728 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0486324 |
| S100A10 | S100 calcium binding protein A10 | -0.0477427 |
| EHBP1 | EH domain binding protein 1 | -0.0473486 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0471465 |
| AHNAK | AHNAK nucleoprotein | -0.046555 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0453145 |
| DTNA | dystrobrevin, alpha | -0.0429717 |
| HMGA1 | high mobility group AT-hook 1 | -0.0429691 |
| TPM4 | tropomyosin 4 | -0.0427209 |
| RAD51B | RAD51 paralog B | -0.041919 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0418722 |
| DSG2 | desmoglein 2 | -0.0416544 |
| ANXA2 | annexin A2 | -0.0407658 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0399863 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0395102 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0393196 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0392697 |
| RRBP1 | ribosome binding protein 1 | -0.0385153 |
| RPL23 | ribosomal protein L23 | -0.0381178 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0375719 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0375635 |
| FLNB | filamin B, beta | -0.0371153 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0364098 |
| ACTG1 | actin gamma 1 | -0.0363961 |
| FTL | ferritin, light polypeptide | -0.0363298 |
| MYO1E | myosin IE | -0.0361909 |
| VIM | vimentin | -0.0358496 |
| EFNA5 | ephrin-A5 | -0.0357709 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.034765 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0346645 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0345175 |
| ASPH | aspartate beta-hydroxylase | -0.034503 |
| LAMC2 | laminin, gamma 2 | -0.0342997 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0340048 |
| ENO1 | enolase 1, (alpha) | -0.0339323 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0336229 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0324672 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.032064 |
| PLAT | plasminogen activator, tissue | -0.031579 |
| LAMA4 | laminin, alpha 4 | -0.0312654 |
| RPS8 | ribosomal protein S8 | -0.030717 |
| CD2AP | CD2-associated protein | -0.0305303 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0304617 |
| MEF2A | myocyte enhancer factor 2A | -0.0302218 |
| S100A11 | S100 calcium binding protein A11 | -0.0300843 |
| ITGA6 | integrin, alpha 6 | -0.0298856 |
| OSMR | oncostatin M receptor | -0.0297131 |
| NCKAP5 | NCK-associated protein 5 | -0.0294496 |
| CSTB | cystatin B (stefin B) | -0.0294186 |
| PKM | pyruvate kinase, muscle | -0.0292999 |
| RPLP1 | ribosomal protein, large, P1 | -0.029146 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0289426 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0287657 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0284219 |
| RPL19 | ribosomal protein L19 | -0.0282189 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0282042 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0280533 |
| RAI14 | retinoic acid induced 14 | -0.0278185 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0276354 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0274565 |
| DST | dystonin | -0.0271274 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0268755 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0267173 |
| RNF213 | ring finger protein 213 | -0.0265696 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264118 |
| SP100 | SP100 nuclear antigen | -0.0263236 |
| HLA-A | major histocompatibility complex, class I, A | -0.0261347 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0261347 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0260902 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0260892 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0260855 |
| PARD3 | par-3 family cell polarity regulator | -0.0260854 |
| HMGA2 | high mobility group AT-hook 2 | -0.0259488 |
| RPL37A | ribosomal protein L37a | -0.0256125 |
| RPL35A | ribosomal protein L35a | -0.0254948 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0253185 |