Ouabain (Octahydrate)_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ouabain (Octahydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ouabain (Octahydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TPT1 tumor protein, translationally-controlled 1 0.0618973
B2M beta-2-microglobulin 0.0607949
SQSTM1 sequestosome 1 0.0563368
FTL ferritin, light polypeptide 0.0468758
PTMA prothymosin, alpha 0.0468668
RAB7A RAB7A, member RAS oncogene family 0.0463296
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0392584
FNIP1 folliculin interacting protein 1 0.0381845
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.037433
AREG amphiregulin 0.0365165
EIF1 eukaryotic translation initiation factor 1 0.0310519
INTS6 integrator complex subunit 6 0.0310064
GCLC glutamate-cysteine ligase, catalytic subunit 0.0309058
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.028505
FTH1 ferritin, heavy polypeptide 1 0.0263467
RPL35A ribosomal protein L35a 0.0256282
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.025442
PLSCR2 phospholipid scramblase 2 0.0248574
SLC38A2 solute carrier family 38, member 2 0.0248091
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0232006
HSPH1 heat shock 105kDa/110kDa protein 1 0.0230577
NDRG1 N-myc downstream regulated 1 0.0229683
AKR1C2 aldo-keto reductase family 1, member C2 0.0225651
LYZ lysozyme 0.0219113
FAF1 Fas (TNFRSF6) associated factor 1 0.0215393
RPS6 ribosomal protein S6 0.0207587
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0202128
MCTP1 multiple C2 domains, transmembrane 1 0.0195015
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0192585
EGR1 early growth response 1 0.019162
LCN2 lipocalin 2 0.0186001
SPAG9 sperm associated antigen 9 0.018028
TM4SF19 transmembrane 4 L six family member 19 0.0178183
ACTG1 actin gamma 1 0.0177315
ZNF292 zinc finger protein 292 0.0176942
TFRC transferrin receptor 0.0176138
HLA-B major histocompatibility complex, class I, B 0.0175236
S100A6 S100 calcium binding protein A6 0.0171994
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0169356
MED13 mediator complex subunit 13 0.016893
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0165674
MT2A metallothionein 2A 0.016383
RPL34 ribosomal protein L34 0.0161027
MCL1 myeloid cell leukemia 1 0.0160572
TM4SF1 transmembrane 4 L six family member 1 0.0159764
RPL31 ribosomal protein L31 0.0159289
IGFBP3 insulin-like growth factor binding protein 3 0.0157901
RPL9 ribosomal protein L9 0.0157817
LOC102724023 ES1 protein homolog, mitochondrial 0.0156758
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0156648
USP34 ubiquitin specific peptidase 34 0.0150345
ZSWIM6 zinc finger, SWIM-type containing 6 0.0149465
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.014769
SIK3 SIK family kinase 3 0.0147074
SMAD3 SMAD family member 3 0.0145881
PRRC2C proline-rich coiled-coil 2C 0.0142661
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0141842
RPL37A ribosomal protein L37a 0.0140803
INSIG1 insulin induced gene 1 0.0139704
TMSB10 thymosin beta 10 0.0137838
MUC20 mucin 20, cell surface associated 0.013625
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0133228
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0133152
DSCAM Down syndrome cell adhesion molecule 0.0132877
OSBPL8 oxysterol binding protein-like 8 0.0128387
PKM pyruvate kinase, muscle 0.0127332
KPNB1 karyopherin (importin) beta 1 0.0124004
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0123832
RPS16 ribosomal protein S16 0.0123395
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.0123264
SON SON DNA binding protein 0.0122875
ANXA2 annexin A2 0.0122367
RPLP1 ribosomal protein, large, P1 0.0122138
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.0119987
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0119166
PERP PERP, TP53 apoptosis effector 0.0118983
RPS12 ribosomal protein S12 0.0118651
RPLP2 ribosomal protein, large, P2 0.0118304
PUM2 pumilio RNA-binding family member 2 0.0118014
AHI1 Abelson helper integration site 1 0.011748
RPS29 ribosomal protein S29 0.0116555
RLF rearranged L-myc fusion 0.0116458
RPS24 ribosomal protein S24 0.0114855
NUP58 nucleoporin 58 0.0114526
NIPBL Nipped-B homolog (Drosophila) 0.0114134
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0113548
HLA-A major histocompatibility complex, class I, A 0.0112222
GMDS GDP-mannose 4,6-dehydratase 0.0111893
RPS19 ribosomal protein S19 0.0111192
RPL7A ribosomal protein L7a 0.011102
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.0110136
TOP1 topoisomerase (DNA) I 0.0109955
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0109833
POMP proteasome maturation protein 0.0109763
SDC4 syndecan 4 0.0108982
SPINK1 serine peptidase inhibitor, Kazal type 1 0.0108408
FDPS farnesyl diphosphate synthase 0.010787
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0107429
ADM adrenomedullin 0.0107417
RPL23 ribosomal protein L23 0.0107122

decreased expression

Symbol Name Standardized Value
BTBD9 BTB (POZ) domain containing 9 -0.0694369
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0491815
ZMYND8 zinc finger, MYND-type containing 8 -0.0416593
MBNL2 muscleblind-like splicing regulator 2 -0.0392136
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0345678
NCKAP5 NCK-associated protein 5 -0.033286
UBC ubiquitin C -0.0330941
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0327365
ZBTB20 zinc finger and BTB domain containing 20 -0.0309116
RUNX1 runt-related transcription factor 1 -0.0298371
RNF43 ring finger protein 43 -0.0297096
PHF3 PHD finger protein 3 -0.0294069
PTBP3 polypyrimidine tract binding protein 3 -0.0291482
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0272791
EPSTI1 epithelial stromal interaction 1 (breast) -0.0268519
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0264253
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.0260638
MACC1 metastasis associated in colon cancer 1 -0.0259956
FNDC3A fibronectin type III domain containing 3A -0.02597
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0255606
TRIM2 tripartite motif containing 2 -0.0252901
PLSCR1 phospholipid scramblase 1 -0.0249953
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -0.0249084
AHNAK AHNAK nucleoprotein -0.0241728
TMEM62 transmembrane protein 62 -0.023379
PRELID2 PRELI domain containing 2 -0.0227758
STK24 serine/threonine kinase 24 -0.0226058
PARP4 poly (ADP-ribose) polymerase family, member 4 -0.0224164
SPATA13 spermatogenesis associated 13 -0.0222648
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0212255
NKD1 naked cuticle homolog 1 (Drosophila) -0.0211306
RAD51B RAD51 paralog B -0.0207235
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0195233
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0193601
EPHB2 EPH receptor B2 -0.0192679
MEIS2 Meis homeobox 2 -0.0190685
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0180875
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0176009
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.0174674
EHF ets homologous factor -0.0172846
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0170234
MYO1E myosin IE -0.0167967
RRBP1 ribosome binding protein 1 -0.0166728
ETV6 ets variant 6 -0.0165583
ATP11A ATPase, class VI, type 11A -0.0165172
OARD1 O-acyl-ADP-ribose deacylase 1 -0.0164835
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0161577
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -0.01614
MSI2 musashi RNA-binding protein 2 -0.0160276
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0159469
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0159449
RHOBTB3 Rho-related BTB domain containing 3 -0.0159345
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0159218
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0157754
PTEN phosphatase and tensin homolog -0.0157361
FOXP1 forkhead box P1 -0.0156475
PDIA3 protein disulfide isomerase family A, member 3 -0.0156134
MECOM MDS1 and EVI1 complex locus -0.0155235
FMN1 formin 1 -0.0154378
COG6 component of oligomeric golgi complex 6 -0.0153841
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0150709
LMO7 LIM domain 7 -0.0150455
ATP10B ATPase, class V, type 10B -0.0150302
SEC24D SEC24 family member D -0.0146615
ABHD2 abhydrolase domain containing 2 -0.0141687
HDAC4 histone deacetylase 4 -0.0141616
ESRP1 epithelial splicing regulatory protein 1 -0.0139581
KIAA1217 KIAA1217 -0.0139336
SORBS1 sorbin and SH3 domain containing 1 -0.0138071
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0138061
CPEB4 cytoplasmic polyadenylation element binding protein 4 -0.0137665
IGF1R insulin-like growth factor 1 receptor -0.0137456
TTC3 tetratricopeptide repeat domain 3 -0.013693
MX1 MX dynamin-like GTPase 1 -0.0135785
NRIP1 nuclear receptor interacting protein 1 -0.0134374
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0133234
RABGAP1L RAB GTPase activating protein 1-like -0.0132732
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) -0.0132371
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0130937
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0129736
IL20RA interleukin 20 receptor, alpha -0.0129721
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0129191
SPATS2L spermatogenesis associated, serine-rich 2-like -0.012827
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0128147
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -0.012798
MCTP2 multiple C2 domains, transmembrane 2 -0.012681
ACTN4 actinin, alpha 4 -0.0126302
AKAP9 A kinase (PRKA) anchor protein 9 -0.0125457
PDIA4 protein disulfide isomerase family A, member 4 -0.0125078
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.0124873
SPRED2 sprouty-related, EVH1 domain containing 2 -0.01248
RERE arginine-glutamic acid dipeptide (RE) repeats -0.012347
ALPK1 alpha-kinase 1 -0.0122046
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.0121528
MYH9 myosin, heavy chain 9, non-muscle -0.011939
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.0118747
PRKCA protein kinase C, alpha -0.0118077
MON2 MON2 homolog (S. cerevisiae) -0.011759
GOLGB1 golgin B1 -0.0117537
ARB2A ARB2 cotranscriptional regulator A -0.0116881