| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.0470562 |
| ZNF292 | zinc finger protein 292 | 0.0465861 |
| GOLGA4 | golgin A4 | 0.0454853 |
| MATR3 | matrin 3 | 0.0440834 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0421229 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0410904 |
| CCNL1 | cyclin L1 | 0.0361972 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0358976 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0337256 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0324891 |
| RNF145 | ring finger protein 145 | 0.0303225 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0298229 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0280206 |
| RPL3 | ribosomal protein L3 | 0.0252396 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0252031 |
| APP | amyloid beta (A4) precursor protein | 0.0250651 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0241408 |
| SETD2 | SET domain containing 2 | 0.0238577 |
| RLF | rearranged L-myc fusion | 0.0238063 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0232071 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0227475 |
| FTL | ferritin, light polypeptide | 0.0226904 |
| NCKAP1 | NCK-associated protein 1 | 0.0220571 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0216336 |
| TXNRD1 | thioredoxin reductase 1 | 0.0201645 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0200825 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0193476 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0189548 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0189505 |
| YTHDC1 | YTH domain containing 1 | 0.0184794 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0184038 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0182191 |
| PCBP2 | poly(rC) binding protein 2 | 0.0180683 |
| SNX9 | sorting nexin 9 | 0.0180495 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0180463 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0178085 |
| MED13 | mediator complex subunit 13 | 0.0177761 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.017667 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0175911 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0175896 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0175497 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0174813 |
| CREBRF | CREB3 regulatory factor | 0.0172983 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0171476 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0170166 |
| USP3 | ubiquitin specific peptidase 3 | 0.0169585 |
| ZNF148 | zinc finger protein 148 | 0.0169441 |
| ITSN2 | intersectin 2 | 0.0168149 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0167594 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0165576 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.016548 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0164248 |
| DSTN | destrin (actin depolymerizing factor) | 0.0162968 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0162374 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.016176 |
| YBX1 | Y box binding protein 1 | 0.0161611 |
| PDS5B | PDS5 cohesin associated factor B | 0.0159615 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0159255 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0158686 |
| SPOPL | speckle-type POZ protein-like | 0.0158533 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.015852 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.01585 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0158026 |
| QKI | QKI, KH domain containing, RNA binding | 0.0153368 |
| PHIP | pleckstrin homology domain interacting protein | 0.0152484 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0151582 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0151087 |
| RIOK3 | RIO kinase 3 | 0.0150283 |
| RBM27 | RNA binding motif protein 27 | 0.0148666 |
| SNX2 | sorting nexin 2 | 0.0148235 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.014821 |
| TMEM41B | transmembrane protein 41B | 0.0147944 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0146368 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0146286 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0145797 |
| SPAG9 | sperm associated antigen 9 | 0.0144531 |
| CCNT2 | cyclin T2 | 0.0143424 |
| SLMAP | sarcolemma associated protein | 0.0140663 |
| FOSL1 | FOS-like antigen 1 | 0.0140098 |
| CRY1 | cryptochrome circadian clock 1 | 0.0140063 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0139243 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0139176 |
| HELZ | helicase with zinc finger | 0.0139027 |
| SRPK2 | SRSF protein kinase 2 | 0.013756 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0137536 |
| ATP11B | ATPase, class VI, type 11B | 0.0136374 |
| USP47 | ubiquitin specific peptidase 47 | 0.0135437 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.013445 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.0133765 |
| ORC4 | origin recognition complex, subunit 4 | 0.0133592 |
| SNX4 | sorting nexin 4 | 0.013328 |
| NUP54 | nucleoporin 54kDa | 0.013192 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0131793 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0131679 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0131647 |
| TMF1 | TATA element modulatory factor 1 | 0.0131047 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0130402 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0129769 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0128776 |
| MLF1 | myeloid leukemia factor 1 | 0.0127742 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.193381 |
| PRELID2 | PRELI domain containing 2 | -0.151013 |
| RAD51B | RAD51 paralog B | -0.123544 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.114531 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.113142 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.110272 |
| AHNAK | AHNAK nucleoprotein | -0.104456 |
| FHIT | fragile histidine triad | -0.0993258 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.097144 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0945077 |
| HMGA2 | high mobility group AT-hook 2 | -0.0893092 |
| TMSB10 | thymosin beta 10 | -0.0827983 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0817719 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0805285 |
| WWOX | WW domain containing oxidoreductase | -0.0772521 |
| EGFR | epidermal growth factor receptor | -0.0765651 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0762524 |
| SMYD3 | SET and MYND domain containing 3 | -0.0727877 |
| PAX8 | paired box 8 | -0.0723079 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0691704 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0686629 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.065228 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0622639 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0605313 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0593456 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0593196 |
| SVIL | supervillin | -0.0581471 |
| CD44 | CD44 molecule (Indian blood group) | -0.0580675 |
| DIAPH3 | diaphanous-related formin 3 | -0.0578813 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0577083 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0573658 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0570815 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0569412 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0549237 |
| ACTG1 | actin gamma 1 | -0.0524788 |
| FLNB | filamin B, beta | -0.0517745 |
| ATXN1 | ataxin 1 | -0.0512361 |
| MACROD2 | MACRO domain containing 2 | -0.0511016 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0510826 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0503639 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0501143 |
| EXOC4 | exocyst complex component 4 | -0.0495908 |
| ATG7 | autophagy related 7 | -0.0495746 |
| CCND1 | cyclin D1 | -0.0491664 |
| NDRG1 | N-myc downstream regulated 1 | -0.0466739 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0460034 |
| FLNA | filamin A, alpha | -0.0453864 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.044452 |
| LAMC2 | laminin, gamma 2 | -0.0443052 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0435135 |
| TPM4 | tropomyosin 4 | -0.0434932 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0434928 |
| ITGA6 | integrin, alpha 6 | -0.0428279 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0425955 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0418034 |
| MYOF | myoferlin | -0.0413306 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0410262 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0404732 |
| SPATA13 | spermatogenesis associated 13 | -0.0404601 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.040387 |
| SUMF1 | sulfatase modifying factor 1 | -0.0403596 |
| VCL | vinculin | -0.0399719 |
| LAMA4 | laminin, alpha 4 | -0.0399571 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0392653 |
| DENND1A | DENN/MADD domain containing 1A | -0.0391477 |
| SEPTIN9 | septin 9 | -0.0388188 |
| LAMB3 | laminin, beta 3 | -0.0383442 |
| ACTN4 | actinin, alpha 4 | -0.0380666 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0375628 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0374603 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0374081 |
| PCED1B | PC-esterase domain containing 1B | -0.0371786 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0371143 |
| RNF213 | ring finger protein 213 | -0.0370256 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0369296 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0364639 |
| EHBP1 | EH domain binding protein 1 | -0.0359701 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0354529 |
| MYO1E | myosin IE | -0.0354471 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0354468 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.035091 |
| MAP4 | microtubule-associated protein 4 | -0.0348848 |
| LDHA | lactate dehydrogenase A | -0.0340609 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.033903 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0338746 |
| MT2A | metallothionein 2A | -0.0336358 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0336253 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0335399 |
| AEBP2 | AE binding protein 2 | -0.0333326 |
| KRT7 | keratin 7, type II | -0.0328932 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0326455 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.032642 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.0323052 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0322909 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0322768 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0321078 |
| GPR39 | G protein-coupled receptor 39 | -0.03182 |
| PLEC | plectin | -0.0315391 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0314926 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0311818 |
