| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.136487 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0927069 |
| FAM13A | family with sequence similarity 13, member A | 0.0889566 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0783766 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0709626 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0662715 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0636189 |
| NUP58 | nucleoporin 58 | 0.0603378 |
| SPAG9 | sperm associated antigen 9 | 0.0589434 |
| RLF | rearranged L-myc fusion | 0.0563266 |
| ZNF292 | zinc finger protein 292 | 0.0511534 |
| USP3 | ubiquitin specific peptidase 3 | 0.0497999 |
| MT2A | metallothionein 2A | 0.0479911 |
| ADM | adrenomedullin | 0.0459953 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0451748 |
| ATP13A3 | ATPase type 13A3 | 0.0446179 |
| WDR45B | WD repeat domain 45B | 0.0440541 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0431697 |
| RNF145 | ring finger protein 145 | 0.0415676 |
| QKI | QKI, KH domain containing, RNA binding | 0.0415319 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0412439 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.039392 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0375025 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0366703 |
| GOLGA4 | golgin A4 | 0.0364245 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0363626 |
| THBS1 | thrombospondin 1 | 0.0358452 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0351345 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0349997 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0348478 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0340664 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0337976 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.033017 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0323792 |
| SETD5 | SET domain containing 5 | 0.0323247 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0319158 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0314643 |
| RNF24 | ring finger protein 24 | 0.0313774 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0313423 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0299182 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.029807 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296291 |
| STC1 | stanniocalcin 1 | 0.0295008 |
| RND3 | Rho family GTPase 3 | 0.0292492 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0290501 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0286385 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0282254 |
| FAM162A | family with sequence similarity 162, member A | 0.0281327 |
| JUN | jun proto-oncogene | 0.0279809 |
| PTMA | prothymosin, alpha | 0.0275027 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0272975 |
| CENPF | centromere protein F, 350/400kDa | 0.0269891 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0265523 |
| ARRDC3 | arrestin domain containing 3 | 0.0265401 |
| TFRC | transferrin receptor | 0.0265321 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0263439 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0262852 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0259547 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0258627 |
| RYBP | RING1 and YY1 binding protein | 0.0257731 |
| OGA | O-GlcNAcase | 0.0256509 |
| IER3 | immediate early response 3 | 0.0254563 |
| CRY1 | cryptochrome circadian clock 1 | 0.0254109 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0252787 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0249283 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0248098 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0246576 |
| HELZ | helicase with zinc finger | 0.0245269 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0244621 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0243446 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0242153 |
| RBM39 | RNA binding motif protein 39 | 0.0241886 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0241352 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0237017 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0235693 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0235314 |
| INSIG2 | insulin induced gene 2 | 0.0233929 |
| NUP153 | nucleoporin 153kDa | 0.0233042 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0231982 |
| CD109 | CD109 molecule | 0.0231707 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0228666 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.022858 |
| CCNL1 | cyclin L1 | 0.0227579 |
| ECT2 | epithelial cell transforming 2 | 0.022531 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0222968 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0220463 |
| YBX3 | Y box binding protein 3 | 0.0219243 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0211276 |
| SNX9 | sorting nexin 9 | 0.021027 |
| PER1 | period circadian clock 1 | 0.0208765 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0206135 |
| NPTN | neuroplastin | 0.0205262 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0205147 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0204926 |
| G0S2 | G0/G1 switch 2 | 0.0204874 |
| NOP58 | NOP58 ribonucleoprotein | 0.0201387 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0200728 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0194887 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0193438 |
| VIM | vimentin | 0.0191195 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.196326 |
| HMGA2 | high mobility group AT-hook 2 | -0.191308 |
| COL5A1 | collagen, type V, alpha 1 | -0.176812 |
| CDH13 | cadherin 13 | -0.145615 |
| NAV1 | neuron navigator 1 | -0.131665 |
| COL6A3 | collagen, type VI, alpha 3 | -0.112447 |
| EXT1 | exostosin glycosyltransferase 1 | -0.103428 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.101684 |
| ASPH | aspartate beta-hydroxylase | -0.097716 |
| FN1 | fibronectin 1 | -0.0919976 |
| GLIS3 | GLIS family zinc finger 3 | -0.0900894 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.086205 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0840065 |
| AHNAK | AHNAK nucleoprotein | -0.0822931 |
| MYO10 | myosin X | -0.0776625 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0723905 |
| VCL | vinculin | -0.0711663 |
| PRELID2 | PRELI domain containing 2 | -0.0706687 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0669672 |
| DST | dystonin | -0.0665827 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0638213 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0617302 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0613739 |
| RAI14 | retinoic acid induced 14 | -0.0599777 |
| ATXN1 | ataxin 1 | -0.0597145 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.058432 |
| SMYD3 | SET and MYND domain containing 3 | -0.0567031 |
| RAD51B | RAD51 paralog B | -0.0562727 |
| DIAPH2 | diaphanous-related formin 2 | -0.0545914 |
| PRKCA | protein kinase C, alpha | -0.0526981 |
| FMN1 | formin 1 | -0.0515948 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0505405 |
| ACTG1 | actin gamma 1 | -0.049953 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0473623 |
| SEPTIN9 | septin 9 | -0.0473573 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0473534 |
| EGFR | epidermal growth factor receptor | -0.0469042 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0468407 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0466592 |
| EFNA5 | ephrin-A5 | -0.0465171 |
| TENM2 | teneurin transmembrane protein 2 | -0.0456546 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0453021 |
| TMSB10 | thymosin beta 10 | -0.0438951 |
| AFF3 | AF4/FMR2 family, member 3 | -0.04293 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0428448 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0402301 |
| PCBP3 | poly(rC) binding protein 3 | -0.039978 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0399064 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0389123 |
| CCDC91 | coiled-coil domain containing 91 | -0.0384056 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0382642 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0377006 |
| FRMD4A | FERM domain containing 4A | -0.0372954 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0368932 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.036076 |
| PLEC | plectin | -0.0357419 |
| CLMP | CXADR-like membrane protein | -0.0355114 |
| IGF2 | insulin-like growth factor 2 | -0.0354318 |
| KIAA1549L | KIAA1549-like | -0.0354207 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0350704 |
| RRBP1 | ribosome binding protein 1 | -0.0348152 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0344616 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0335843 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0330442 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0328983 |
| CFAP20DC | CFAP20 domain containing | -0.032809 |
| WWOX | WW domain containing oxidoreductase | -0.0327177 |
| LAMB3 | laminin, beta 3 | -0.0324947 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0323692 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0319741 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0319089 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0315669 |
| CUX1 | cut-like homeobox 1 | -0.0314003 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0307339 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0305324 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0305126 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0303762 |
| PRSS23 | protease, serine, 23 | -0.0297874 |
| EHBP1 | EH domain binding protein 1 | -0.0294268 |
| CLIC4 | chloride intracellular channel 4 | -0.0294062 |
| EXOC4 | exocyst complex component 4 | -0.0293989 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0292874 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.028385 |
| INTS6 | integrator complex subunit 6 | -0.0280562 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0280534 |
| MYO9A | myosin IXA | -0.0279034 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0278434 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0275208 |
| TBC1D5 | TBC1 domain family, member 5 | -0.027134 |
| ETV6 | ets variant 6 | -0.0271143 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.02684 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0264289 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0262651 |
| LOXL2 | lysyl oxidase-like 2 | -0.0261154 |
| TPM1 | tropomyosin 1 (alpha) | -0.0260077 |
| NABP1 | nucleic acid binding protein 1 | -0.0259653 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0257446 |
| ACTN1 | actinin, alpha 1 | -0.0256289 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0254395 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0251896 |
