| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | 0.182103 |
| VIM | vimentin | 0.111312 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.106763 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.10442 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.103287 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0814871 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0666108 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0663147 |
| PTMA | prothymosin, alpha | 0.0527255 |
| IER3 | immediate early response 3 | 0.0467745 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0453835 |
| MT2A | metallothionein 2A | 0.0441352 |
| INSIG1 | insulin induced gene 1 | 0.0434327 |
| CADM1 | cell adhesion molecule 1 | 0.0429117 |
| ENO1 | enolase 1, (alpha) | 0.0409735 |
| COL1A2 | collagen, type I, alpha 2 | 0.0394346 |
| RPL35A | ribosomal protein L35a | 0.0392515 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0391486 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0364237 |
| HLA-B | major histocompatibility complex, class I, B | 0.0362102 |
| RPS8 | ribosomal protein S8 | 0.0353035 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0353016 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0341306 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0338102 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0337383 |
| TMSB10 | thymosin beta 10 | 0.0334219 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0333792 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0327361 |
| CD44 | CD44 molecule (Indian blood group) | 0.032392 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0304182 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0300997 |
| CALU | calumenin | 0.0296529 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.02931 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0288835 |
| ATP13A3 | ATPase type 13A3 | 0.0288501 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0270858 |
| SPAG9 | sperm associated antigen 9 | 0.0266471 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0265957 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0265501 |
| B2M | beta-2-microglobulin | 0.0262381 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0261188 |
| FNIP1 | folliculin interacting protein 1 | 0.0261155 |
| RPL37A | ribosomal protein L37a | 0.0258794 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0257056 |
| SMAD3 | SMAD family member 3 | 0.0255138 |
| INHBA | inhibin, beta A | 0.0249887 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0242794 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0241943 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0241551 |
| CAVIN1 | caveolae associated protein 1 | 0.0235647 |
| CCNL1 | cyclin L1 | 0.0234101 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0228059 |
| COL3A1 | collagen, type III, alpha 1 | 0.0226269 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0224323 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0220282 |
| PTK2 | protein tyrosine kinase 2 | 0.0217068 |
| FAT1 | FAT atypical cadherin 1 | 0.0215951 |
| RPL11 | ribosomal protein L11 | 0.0215356 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.021453 |
| FTL | ferritin, light polypeptide | 0.0210689 |
| RPS13 | ribosomal protein S13 | 0.0202225 |
| TFRC | transferrin receptor | 0.0201896 |
| SQSTM1 | sequestosome 1 | 0.02016 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0200344 |
| GOLGA4 | golgin A4 | 0.0197929 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0197762 |
| STC1 | stanniocalcin 1 | 0.0196158 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0192993 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.0191891 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0191847 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0190455 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0190266 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.0189341 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0189237 |
| RPS25 | ribosomal protein S25 | 0.0188151 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0187666 |
| CALR | calreticulin | 0.018693 |
| RPL37 | ribosomal protein L37 | 0.0183124 |
| MED13 | mediator complex subunit 13 | 0.0182775 |
| ADM | adrenomedullin | 0.0182661 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0180834 |
| IRF1 | interferon regulatory factor 1 | 0.0177591 |
| RPL34 | ribosomal protein L34 | 0.0175049 |
| PTX3 | pentraxin 3, long | 0.0172871 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0172745 |
| THBS1 | thrombospondin 1 | 0.0167939 |
| RPS3 | ribosomal protein S3 | 0.0166594 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0165042 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0163004 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0161187 |
| RPS6 | ribosomal protein S6 | 0.0161016 |
| CCND1 | cyclin D1 | 0.0160751 |
| RPLP2 | ribosomal protein, large, P2 | 0.0159815 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0159327 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0158384 |
| TMSB4X | thymosin beta 4, X-linked | 0.0157755 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0157527 |
| RBM39 | RNA binding motif protein 39 | 0.0156483 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0153686 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0151644 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.221241 |
| FN1 | fibronectin 1 | -0.170558 |
| COL6A3 | collagen, type VI, alpha 3 | -0.113467 |
| NDRG1 | N-myc downstream regulated 1 | -0.069112 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0620123 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0555803 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0542941 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0508401 |
| PDE10A | phosphodiesterase 10A | -0.0497274 |
| COL5A1 | collagen, type V, alpha 1 | -0.0488933 |
| PRELID2 | PRELI domain containing 2 | -0.0447205 |
| VEGFA | vascular endothelial growth factor A | -0.0413891 |
| CDH13 | cadherin 13 | -0.0372028 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0352476 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0350569 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0340583 |
| MAP1B | microtubule-associated protein 1B | -0.0337332 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0318102 |
| LOXL2 | lysyl oxidase-like 2 | -0.0292849 |
| LOX | lysyl oxidase | -0.0292805 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0267719 |
| FBN1 | fibrillin 1 | -0.0259106 |
| SMYD3 | SET and MYND domain containing 3 | -0.025737 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.025362 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0235738 |
| GLIS3 | GLIS family zinc finger 3 | -0.0227951 |
| AHNAK | AHNAK nucleoprotein | -0.0220832 |
| DST | dystonin | -0.0220474 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0219488 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0211321 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.021033 |
| NAV1 | neuron navigator 1 | -0.019963 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0198736 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0189601 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0185376 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.018489 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0183328 |
| TRAM2 | translocation associated membrane protein 2 | -0.0180701 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0176133 |
| EPHB1 | EPH receptor B1 | -0.0175077 |
| EGFR | epidermal growth factor receptor | -0.0174723 |
| PLEC | plectin | -0.0170636 |
| ASPH | aspartate beta-hydroxylase | -0.0164114 |
| ANO6 | anoctamin 6 | -0.0162363 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0162221 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0161824 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0160526 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0159835 |
| VCAN | versican | -0.0157902 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0156402 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0155104 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0151979 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0151967 |
| FAM13A | family with sequence similarity 13, member A | -0.0151741 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0150233 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0146622 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0146415 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0145872 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0144505 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0143466 |
| HYOU1 | hypoxia up-regulated 1 | -0.0142473 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.014094 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0140427 |
| YEATS2 | YEATS domain containing 2 | -0.0135968 |
| RAD51B | RAD51 paralog B | -0.0135502 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0135028 |
| TNS1 | tensin 1 | -0.0134813 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0133609 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0133468 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0133166 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0132503 |
| ECE1 | endothelin converting enzyme 1 | -0.0132161 |
| FLNB | filamin B, beta | -0.0128902 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0127405 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0126176 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0125969 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0125512 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.012466 |
| EXOC4 | exocyst complex component 4 | -0.0122042 |
| NBEAL1 | neurobeachin-like 1 | -0.0119876 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0119702 |
| DOCK7 | dedicator of cytokinesis 7 | -0.0119662 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0119224 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0119208 |
| MAP4 | microtubule-associated protein 4 | -0.0116991 |
| HMGA1 | high mobility group AT-hook 1 | -0.011678 |
| SETBP1 | SET binding protein 1 | -0.0115434 |
| CD109 | CD109 molecule | -0.011306 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.011305 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0112465 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0111809 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0110575 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0110556 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0110203 |
| VEGFC | vascular endothelial growth factor C | -0.0110115 |
| CANX | calnexin | -0.0108258 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0108069 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.0107478 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0106231 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0106195 |
