| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.0837688 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0715754 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0676982 |
| FNIP1 | folliculin interacting protein 1 | 0.0663732 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0544503 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0510815 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0498727 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.044409 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0408952 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0394569 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0392488 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0392107 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0389537 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0368144 |
| ZNF207 | zinc finger protein 207 | 0.0360817 |
| SPAG9 | sperm associated antigen 9 | 0.0357378 |
| SQSTM1 | sequestosome 1 | 0.0356871 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347846 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.034758 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0347252 |
| TOP1 | topoisomerase (DNA) I | 0.0343479 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0341835 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0341195 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0329445 |
| OGA | O-GlcNAcase | 0.0328296 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.031543 |
| JMJD1C | jumonji domain containing 1C | 0.0314011 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0313421 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0312545 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0310125 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0308441 |
| MED13 | mediator complex subunit 13 | 0.0299545 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0293966 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0290218 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0288179 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0285973 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0283132 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.028107 |
| CCNL1 | cyclin L1 | 0.027319 |
| CRY1 | cryptochrome circadian clock 1 | 0.0272887 |
| HBP1 | HMG-box transcription factor 1 | 0.0272195 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0271502 |
| NUP98 | nucleoporin 98kDa | 0.0270536 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0269401 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0263544 |
| ARRDC4 | arrestin domain containing 4 | 0.0263267 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0261518 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0255816 |
| SLMAP | sarcolemma associated protein | 0.0254378 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0251593 |
| INTS6 | integrator complex subunit 6 | 0.0248995 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0248274 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0246086 |
| RBM39 | RNA binding motif protein 39 | 0.0245872 |
| YTHDC1 | YTH domain containing 1 | 0.0243473 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0241957 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.023386 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0233722 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0231838 |
| NPTN | neuroplastin | 0.0231015 |
| ZNF292 | zinc finger protein 292 | 0.0230541 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0227484 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0223798 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0217777 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0217392 |
| RPL21 | ribosomal protein L21 | 0.0214356 |
| USP47 | ubiquitin specific peptidase 47 | 0.0211758 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.020821 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0208004 |
| WDR26 | WD repeat domain 26 | 0.0207649 |
| PER1 | period circadian clock 1 | 0.0207302 |
| ATOSA | atos homolog A | 0.0205029 |
| ECT2 | epithelial cell transforming 2 | 0.0204563 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.020361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0201923 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0200811 |
| SMAD3 | SMAD family member 3 | 0.0198455 |
| AREG | amphiregulin | 0.0198386 |
| INO80 | INO80 complex subunit | 0.0196725 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0196494 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0195452 |
| ATP13A3 | ATPase type 13A3 | 0.0194303 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.019303 |
| NCKAP1 | NCK-associated protein 1 | 0.0192827 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0192644 |
| MED13L | mediator complex subunit 13-like | 0.0191834 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0189787 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0186922 |
| BRD2 | bromodomain containing 2 | 0.01845 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0184141 |
| NUP58 | nucleoporin 58 | 0.0183202 |
| RYBP | RING1 and YY1 binding protein | 0.0181827 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0180835 |
| SIK3 | SIK family kinase 3 | 0.0179907 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0177587 |
| PCBP2 | poly(rC) binding protein 2 | 0.0176391 |
| RLF | rearranged L-myc fusion | 0.0176013 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0175962 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0175587 |
| ITGAV | integrin, alpha V | 0.0173615 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.112383 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.104586 |
| ANXA2 | annexin A2 | -0.0986356 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.095463 |
| TXNRD1 | thioredoxin reductase 1 | -0.0948978 |
| AHNAK | AHNAK nucleoprotein | -0.091068 |
| ACTN4 | actinin, alpha 4 | -0.0839565 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0817006 |
| KRT18 | keratin 18, type I | -0.0757785 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0753699 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0747311 |
| KRT8 | keratin 8, type II | -0.0700658 |
| NDRG1 | N-myc downstream regulated 1 | -0.0676786 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0667873 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0667448 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0651909 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0647149 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0639402 |
| DIAPH2 | diaphanous-related formin 2 | -0.0627375 |
| TMSB10 | thymosin beta 10 | -0.0625272 |
| PTMA | prothymosin, alpha | -0.0621938 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0597799 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0592765 |
| WASF2 | WAS protein family, member 2 | -0.0576354 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0575415 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0573369 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0571517 |
| LYZ | lysozyme | -0.056389 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0557713 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0554661 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0547309 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0541488 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0531948 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0525635 |
| STK24 | serine/threonine kinase 24 | -0.0507192 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0503847 |
| PGK1 | phosphoglycerate kinase 1 | -0.0498344 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0495726 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0491207 |
| FTL | ferritin, light polypeptide | -0.0485723 |
| EXOC4 | exocyst complex component 4 | -0.0483236 |
| RRBP1 | ribosome binding protein 1 | -0.0480231 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0479808 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0474657 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0471061 |
| FRY | furry homolog (Drosophila) | -0.0456698 |
| ITGA6 | integrin, alpha 6 | -0.0450838 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0445048 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0432929 |
| TMEM123 | transmembrane protein 123 | -0.0429761 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0428003 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0419025 |
| PTK2 | protein tyrosine kinase 2 | -0.0411293 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0410977 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0409719 |
| ASPH | aspartate beta-hydroxylase | -0.0403928 |
| DGKH | diacylglycerol kinase, eta | -0.0397765 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0395603 |
| LAMA4 | laminin, alpha 4 | -0.0383903 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0381703 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0380608 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0379891 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0376305 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0373772 |
| ETV6 | ets variant 6 | -0.0371683 |
| LAMB3 | laminin, beta 3 | -0.0366712 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0366228 |
| UTRN | utrophin | -0.0349556 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0346057 |
| NBEAL1 | neurobeachin-like 1 | -0.0345593 |
| FLNB | filamin B, beta | -0.0342802 |
| S100A6 | S100 calcium binding protein A6 | -0.0340276 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0339205 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0336108 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0335997 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0326848 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0326163 |
| MECOM | MDS1 and EVI1 complex locus | -0.0322847 |
| FOXP1 | forkhead box P1 | -0.0318804 |
| DNM2 | dynamin 2 | -0.0317754 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0316194 |
| CD2AP | CD2-associated protein | -0.0315503 |
| PYGB | phosphorylase, glycogen; brain | -0.0313935 |
| SULF2 | sulfatase 2 | -0.0307122 |
| LDHA | lactate dehydrogenase A | -0.0301659 |
| EFNA5 | ephrin-A5 | -0.0301288 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0300484 |
| HDLBP | high density lipoprotein binding protein | -0.0297598 |
| ACTG1 | actin gamma 1 | -0.0297222 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0296138 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0295604 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0291648 |
| JUP | junction plakoglobin | -0.0291418 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0290671 |
| KLF10 | Kruppel-like factor 10 | -0.0290107 |
| KRT20 | keratin 20, type I | -0.0289279 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0285788 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0283709 |
| EZR | ezrin | -0.0282549 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0281362 |
