| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0833135 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0471099 |
| ASPH | aspartate beta-hydroxylase | 0.0468615 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0364579 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0351739 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0343742 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0338503 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0324655 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.031722 |
| VCL | vinculin | 0.0302645 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0288177 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0283924 |
| DST | dystonin | 0.0283455 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.027837 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0275167 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0273785 |
| MRTFA | myocardin related transcription factor A | 0.0273522 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0272732 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0266137 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0255105 |
| FRMD5 | FERM domain containing 5 | 0.0250623 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0239329 |
| TXNRD1 | thioredoxin reductase 1 | 0.0235415 |
| JAG1 | jagged 1 | 0.0234404 |
| FILIP1L | filamin A interacting protein 1-like | 0.0231282 |
| FAT1 | FAT atypical cadherin 1 | 0.0230644 |
| BRD2 | bromodomain containing 2 | 0.0227993 |
| CDC7 | cell division cycle 7 | 0.0220764 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0219521 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0216614 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0215419 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0211707 |
| SVIL | supervillin | 0.0208601 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0203583 |
| ATXN1 | ataxin 1 | 0.0199366 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0199228 |
| PAPOLA | poly(A) polymerase alpha | 0.0194058 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0190808 |
| RIGI | RNA sensor RIG-I | 0.0190509 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0186086 |
| BCL2L1 | BCL2-like 1 | 0.0179935 |
| RUNX1 | runt-related transcription factor 1 | 0.0178314 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0171696 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0171585 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0170645 |
| RANBP9 | RAN binding protein 9 | 0.0170314 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0169152 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0168363 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0164762 |
| CCDC88A | coiled-coil domain containing 88A | 0.0164647 |
| RASA2 | RAS p21 protein activator 2 | 0.0163209 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0161273 |
| RBM39 | RNA binding motif protein 39 | 0.0161089 |
| PCBP2 | poly(rC) binding protein 2 | 0.0160824 |
| CCNT2 | cyclin T2 | 0.0159113 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0155902 |
| FERMT1 | fermitin family member 1 | 0.0154352 |
| OSMR | oncostatin M receptor | 0.0154187 |
| LPIN2 | lipin 2 | 0.0153803 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0151175 |
| CCNL1 | cyclin L1 | 0.0149743 |
| CD83 | CD83 molecule | 0.0147758 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0146285 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0145661 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0144179 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0143925 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0142273 |
| MCL1 | myeloid cell leukemia 1 | 0.0141902 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0140997 |
| ATP10A | ATPase, class V, type 10A | 0.0140506 |
| NEK7 | NIMA-related kinase 7 | 0.014009 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.013972 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0139589 |
| RNF213 | ring finger protein 213 | 0.0139525 |
| IFRD1 | interferon-related developmental regulator 1 | 0.013849 |
| N4BP1 | NEDD4 binding protein 1 | 0.0137339 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.0136825 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0135887 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0135007 |
| RAB22A | RAB22A, member RAS oncogene family | 0.013464 |
| AHR | aryl hydrocarbon receptor | 0.0134612 |
| RPL3 | ribosomal protein L3 | 0.0133791 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0133677 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0133372 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0132374 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0132252 |
| TLE4 | transducin-like enhancer of split 4 | 0.0132026 |
| RTN4 | reticulon 4 | 0.0131693 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0130422 |
| ITGB5 | integrin, beta 5 | 0.0130089 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0129956 |
| NUP153 | nucleoporin 153kDa | 0.0129512 |
| ABHD3 | abhydrolase domain containing 3 | 0.0129503 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0129498 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0129482 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0128873 |
| LUZP1 | leucine zipper protein 1 | 0.0126861 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0126332 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0125787 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0125041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.285518 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.166134 |
| IGF2 | insulin-like growth factor 2 | -0.144982 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.14039 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.114311 |
| GPC3 | glypican 3 | -0.108693 |
| APOB | apolipoprotein B | -0.106611 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.105465 |
| RPL11 | ribosomal protein L11 | -0.0964559 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0841981 |
| RPS24 | ribosomal protein S24 | -0.0756941 |
| AHSG | alpha-2-HS-glycoprotein | -0.0749789 |
| A2M | alpha-2-macroglobulin | -0.0718393 |
| RPS6 | ribosomal protein S6 | -0.0718163 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.070592 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0694639 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0674438 |
| IER3 | immediate early response 3 | -0.0669046 |
| FTL | ferritin, light polypeptide | -0.0665471 |
| GDF15 | growth differentiation factor 15 | -0.0662092 |
| SDC4 | syndecan 4 | -0.0656566 |
| RPS8 | ribosomal protein S8 | -0.0656149 |
| TF | transferrin | -0.064909 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0629651 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0624787 |
| RPL34 | ribosomal protein L34 | -0.0615176 |
| ENO1 | enolase 1, (alpha) | -0.0608626 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0595907 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0589884 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0585667 |
| KLF6 | Kruppel-like factor 6 | -0.0567525 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0558457 |
| GNAS | GNAS complex locus | -0.0557289 |
| RPLP1 | ribosomal protein, large, P1 | -0.0553436 |
| TRIM26 | tripartite motif containing 26 | -0.0549448 |
| FN1 | fibronectin 1 | -0.0543711 |
| PEG3 | paternally expressed 3 | -0.054323 |
| RACK1 | receptor for activated C kinase 1 | -0.0529759 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0519373 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0511194 |
| RPL37A | ribosomal protein L37a | -0.0494972 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0490158 |
| RPS3 | ribosomal protein S3 | -0.0485631 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0482442 |
| APOE | apolipoprotein E | -0.0475242 |
| RPL35A | ribosomal protein L35a | -0.0470025 |
| RPLP0 | ribosomal protein, large, P0 | -0.0468391 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0463563 |
| RPS19 | ribosomal protein S19 | -0.046316 |
| RPS27A | ribosomal protein S27a | -0.0456621 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0453681 |
| RPL12 | ribosomal protein L12 | -0.0450137 |
| APOA1 | apolipoprotein A-I | -0.0447274 |
| CP | ceruloplasmin (ferroxidase) | -0.0434718 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0422071 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0416753 |
| RPL26 | ribosomal protein L26 | -0.0412305 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0410026 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.040663 |
| DSPP | dentin sialophosphoprotein | -0.0404473 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0399794 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0398326 |
| TMEM123 | transmembrane protein 123 | -0.0396673 |
| RPL23 | ribosomal protein L23 | -0.0396604 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0389395 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0387814 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0385168 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0383752 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0380694 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0377296 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0368904 |
| PTMA | prothymosin, alpha | -0.0361043 |
| RPL31 | ribosomal protein L31 | -0.0354849 |
| RPS12 | ribosomal protein S12 | -0.0344251 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0343509 |
| NDRG1 | N-myc downstream regulated 1 | -0.0342468 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0342394 |
| RPS14 | ribosomal protein S14 | -0.0341194 |
| RRBP1 | ribosome binding protein 1 | -0.0330596 |
| JMJD1C | jumonji domain containing 1C | -0.0330459 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0329963 |
| RPS29 | ribosomal protein S29 | -0.031649 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0316059 |
| MIDN | midnolin | -0.0315991 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.031551 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0308925 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.030851 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0307549 |
| RPS21 | ribosomal protein S21 | -0.0302893 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0302352 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0300943 |
| RPL13A | ribosomal protein L13a | -0.0300828 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0300424 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0296179 |
| RPS25 | ribosomal protein S25 | -0.0295347 |
| RPS16 | ribosomal protein S16 | -0.0293114 |
| RPL37 | ribosomal protein L37 | -0.0292307 |
| GLG1 | golgi glycoprotein 1 | -0.029089 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0290489 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0290474 |
