| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.130035 |
| ATP13A3 | ATPase type 13A3 | 0.0898321 |
| CCNL1 | cyclin L1 | 0.0678675 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0649547 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0629153 |
| NUP58 | nucleoporin 58 | 0.0627907 |
| GOLGA4 | golgin A4 | 0.0569739 |
| NUP153 | nucleoporin 153kDa | 0.0530231 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0519278 |
| ARF4 | ADP-ribosylation factor 4 | 0.0498198 |
| POTEF | POTE ankyrin domain family, member F | 0.049696 |
| MT2A | metallothionein 2A | 0.0490753 |
| MT1X | metallothionein 1X | 0.0450971 |
| PFN1 | profilin 1 | 0.0411827 |
| FOSL1 | FOS-like antigen 1 | 0.039354 |
| TSC22D2 | TSC22 domain family, member 2 | 0.039179 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0386279 |
| B2M | beta-2-microglobulin | 0.0382414 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0380304 |
| PCBP2 | poly(rC) binding protein 2 | 0.0372082 |
| DIAPH3 | diaphanous-related formin 3 | 0.036348 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0361561 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0357903 |
| SPAG9 | sperm associated antigen 9 | 0.0349616 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.034886 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0341008 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0340505 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0332817 |
| TPX2 | TPX2, microtubule-associated | 0.0331056 |
| DEK | DEK proto-oncogene | 0.0328768 |
| ECT2 | epithelial cell transforming 2 | 0.0328088 |
| NOP58 | NOP58 ribonucleoprotein | 0.0318745 |
| MSN | moesin | 0.0316639 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0308093 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0308036 |
| SRP54 | signal recognition particle 54kDa | 0.0296358 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0293451 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0292403 |
| ZNF292 | zinc finger protein 292 | 0.0288889 |
| CRY1 | cryptochrome circadian clock 1 | 0.0284016 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0281282 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0276658 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0275202 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0274979 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0272138 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0270932 |
| CENPF | centromere protein F, 350/400kDa | 0.0265975 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.026338 |
| RBM39 | RNA binding motif protein 39 | 0.0262842 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0261306 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0260186 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0258555 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0257499 |
| TFG | TRK-fused gene | 0.025623 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0253684 |
| RBM25 | RNA binding motif protein 25 | 0.0250483 |
| NCKAP1 | NCK-associated protein 1 | 0.0245884 |
| AXL | AXL receptor tyrosine kinase | 0.0244218 |
| ZNF148 | zinc finger protein 148 | 0.0242573 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0240547 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.023993 |
| PDS5B | PDS5 cohesin associated factor B | 0.023373 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0233511 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0230885 |
| ARRDC3 | arrestin domain containing 3 | 0.0228229 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0227932 |
| WDR43 | WD repeat domain 43 | 0.0225224 |
| RLF | rearranged L-myc fusion | 0.0224737 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0224402 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0222766 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0222561 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0220269 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0216996 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0213978 |
| LATS2 | large tumor suppressor kinase 2 | 0.0210772 |
| SUCO | SUN domain containing ossification factor | 0.0209836 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0205641 |
| TMF1 | TATA element modulatory factor 1 | 0.020506 |
| TXNRD1 | thioredoxin reductase 1 | 0.0203672 |
| MTF2 | metal response element binding transcription factor 2 | 0.0203331 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0202616 |
| FNBP4 | formin binding protein 4 | 0.0202328 |
| QKI | QKI, KH domain containing, RNA binding | 0.0201763 |
| SET | SET nuclear proto-oncogene | 0.0201591 |
| BRD2 | bromodomain containing 2 | 0.0201348 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0199806 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0199702 |
| USP47 | ubiquitin specific peptidase 47 | 0.0199219 |
| RAB18 | RAB18, member RAS oncogene family | 0.0196889 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0194456 |
| CALR | calreticulin | 0.0194283 |
| INSIG1 | insulin induced gene 1 | 0.0194195 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0193045 |
| UBQLN1 | ubiquilin 1 | 0.0192745 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0192109 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0188165 |
| MATR3 | matrin 3 | 0.0186413 |
| SLMAP | sarcolemma associated protein | 0.0183742 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0181871 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0181365 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.283084 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.159984 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.155204 |
| EXT1 | exostosin glycosyltransferase 1 | -0.150279 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.14112 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.132843 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.12481 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.120655 |
| AHNAK | AHNAK nucleoprotein | -0.108062 |
| ASPH | aspartate beta-hydroxylase | -0.096759 |
| INTS6 | integrator complex subunit 6 | -0.0819608 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0775382 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0766037 |
| RAI14 | retinoic acid induced 14 | -0.0743335 |
| GLIS3 | GLIS family zinc finger 3 | -0.0733704 |
| ANXA2 | annexin A2 | -0.071451 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0659328 |
| SMYD3 | SET and MYND domain containing 3 | -0.0632331 |
| FLNB | filamin B, beta | -0.0601424 |
| PRELID2 | PRELI domain containing 2 | -0.0569416 |
| DTNA | dystrobrevin, alpha | -0.0562855 |
| CD44 | CD44 molecule (Indian blood group) | -0.0555829 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0555737 |
| DST | dystonin | -0.0550959 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0542748 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0541234 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0529416 |
| COL5A1 | collagen, type V, alpha 1 | -0.0517339 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0515372 |
| CAVIN1 | caveolae associated protein 1 | -0.051349 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0513339 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0508175 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0489812 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0489575 |
| EGFR | epidermal growth factor receptor | -0.0473826 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0471826 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0470602 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0453905 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0443183 |
| NAV2 | neuron navigator 2 | -0.0439087 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0421451 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0414269 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0408661 |
| NDRG1 | N-myc downstream regulated 1 | -0.0404428 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0404038 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0395054 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0393989 |
| ZNF432 | zinc finger protein 432 | -0.0390773 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0390319 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0383847 |
| DENND1A | DENN/MADD domain containing 1A | -0.0380519 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376149 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0375801 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.03726 |
| NAV1 | neuron navigator 1 | -0.0370284 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0369957 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0367991 |
| STK4 | serine/threonine kinase 4 | -0.0367307 |
| VCL | vinculin | -0.0363932 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0352418 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0351661 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0350832 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0349021 |
| RAD51B | RAD51 paralog B | -0.0339693 |
| ZNF841 | zinc finger protein 841 | -0.0339063 |
| ATXN1 | ataxin 1 | -0.0338815 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0333011 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0319496 |
| CUX1 | cut-like homeobox 1 | -0.0319374 |
| CAST | calpastatin | -0.0317688 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0310918 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0310785 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0301658 |
| AEBP2 | AE binding protein 2 | -0.0299636 |
| KLF12 | Kruppel-like factor 12 | -0.029892 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0297464 |
| HLA-C | major histocompatibility complex, class I, C | -0.0297009 |
| FHIT | fragile histidine triad | -0.0289007 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0288933 |
| HLA-B | major histocompatibility complex, class I, B | -0.02889 |
| FOXP1 | forkhead box P1 | -0.0286072 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.028473 |
| CLIC4 | chloride intracellular channel 4 | -0.0283501 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0281784 |
| TENM3 | teneurin transmembrane protein 3 | -0.0280773 |
| SEPTIN9 | septin 9 | -0.0278936 |
| RIGI | RNA sensor RIG-I | -0.0278376 |
| FRMD6 | FERM domain containing 6 | -0.0276887 |
| ZNF804A | zinc finger protein 804A | -0.0272392 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0271962 |
| MYO1E | myosin IE | -0.0264822 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0261094 |
| SP100 | SP100 nuclear antigen | -0.0261066 |
| ANO4 | anoctamin 4 | -0.0260626 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0260314 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0258897 |
| LOX | lysyl oxidase | -0.0258734 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0256334 |
| RNF213 | ring finger protein 213 | -0.0256132 |
| PODXL | podocalyxin-like | -0.025347 |
