| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MSI2 | musashi RNA-binding protein 2 | 0.0743202 |
| EZR | ezrin | 0.0597186 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0578195 |
| TMSB10 | thymosin beta 10 | 0.0566089 |
| CLDN4 | claudin 4 | 0.0550269 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0531188 |
| ANXA2 | annexin A2 | 0.0491415 |
| CALB1 | calbindin 1, 28kDa | 0.0488256 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0462262 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0458906 |
| COBL | cordon-bleu WH2 repeat protein | 0.0424926 |
| POTEF | POTE ankyrin domain family, member F | 0.0416909 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0396115 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0389249 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0334121 |
| EMP1 | epithelial membrane protein 1 | 0.031074 |
| MT2A | metallothionein 2A | 0.0307986 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0305343 |
| DIAPH1 | diaphanous-related formin 1 | 0.0281465 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0280034 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0279752 |
| ITGA6 | integrin, alpha 6 | 0.0277141 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.027288 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0256419 |
| LAMA4 | laminin, alpha 4 | 0.0253538 |
| SH3D19 | SH3 domain containing 19 | 0.0251507 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0246363 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0243307 |
| RBM25 | RNA binding motif protein 25 | 0.0237908 |
| SHROOM3 | shroom family member 3 | 0.0237793 |
| ENO1 | enolase 1, (alpha) | 0.0235553 |
| S100A6 | S100 calcium binding protein A6 | 0.0232289 |
| SLK | STE20-like kinase | 0.022929 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0228327 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0220224 |
| KRT18 | keratin 18, type I | 0.0214717 |
| BRD2 | bromodomain containing 2 | 0.0209809 |
| ECT2 | epithelial cell transforming 2 | 0.0207061 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0205804 |
| DSPP | dentin sialophosphoprotein | 0.0204284 |
| PERP | PERP, TP53 apoptosis effector | 0.0196822 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.01956 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0189956 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0188179 |
| ETNK1 | ethanolamine kinase 1 | 0.0187633 |
| ANXA11 | annexin A11 | 0.0184703 |
| PTMA | prothymosin, alpha | 0.0182679 |
| PKM | pyruvate kinase, muscle | 0.0178086 |
| KRT19 | keratin 19, type I | 0.017739 |
| PFN1 | profilin 1 | 0.0177167 |
| TJP1 | tight junction protein 1 | 0.017694 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0174386 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0173804 |
| ANXA3 | annexin A3 | 0.0173658 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0173568 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0172645 |
| TUBA1B | tubulin, alpha 1b | 0.0171456 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0171144 |
| HMGA1 | high mobility group AT-hook 1 | 0.0170837 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.016749 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.016621 |
| LDHA | lactate dehydrogenase A | 0.0166134 |
| S100A11 | S100 calcium binding protein A11 | 0.0166075 |
| ANLN | anillin, actin binding protein | 0.0165669 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0164204 |
| MT1X | metallothionein 1X | 0.0163845 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0163441 |
| HLA-B | major histocompatibility complex, class I, B | 0.0162857 |
| FRMD5 | FERM domain containing 5 | 0.0159762 |
| CAV2 | caveolin 2 | 0.0158931 |
| DSG3 | desmoglein 3 | 0.015873 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0158542 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0157994 |
| MAP3K21 | mitogen-activated protein kinase kinase kinase 21 | 0.0156688 |
| MYO5B | myosin VB | 0.0156375 |
| SLTM | SAFB-like, transcription modulator | 0.0153279 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0153216 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0151177 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0150283 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0149635 |
| MED13 | mediator complex subunit 13 | 0.0149379 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0147284 |
| KRT8 | keratin 8, type II | 0.0145756 |
| INSIG1 | insulin induced gene 1 | 0.0145717 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0145451 |
| CDK6 | cyclin-dependent kinase 6 | 0.0145308 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0145219 |
| SLMAP | sarcolemma associated protein | 0.0142082 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0142079 |
| STK39 | serine threonine kinase 39 | 0.0142014 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0141969 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0141823 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0139845 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.013858 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0138499 |
| EPCAM | epithelial cell adhesion molecule | 0.0138339 |
| USP6NL | USP6 N-terminal like | 0.0138305 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0137921 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0137817 |
| LAMC2 | laminin, gamma 2 | 0.0135419 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.131634 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.119073 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0982238 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0973025 |
| RPLP1 | ribosomal protein, large, P1 | -0.0885271 |
| RPS2 | ribosomal protein S2 | -0.0832102 |
| RPS6 | ribosomal protein S6 | -0.0825846 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0743455 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0707841 |
| RAD51B | RAD51 paralog B | -0.0643333 |
| PRELID2 | PRELI domain containing 2 | -0.0564952 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0552758 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0549799 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0539245 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0534046 |
| CANX | calnexin | -0.0515476 |
| RPS8 | ribosomal protein S8 | -0.0514113 |
| ASPH | aspartate beta-hydroxylase | -0.0502875 |
| ATXN1 | ataxin 1 | -0.0499749 |
| SMYD3 | SET and MYND domain containing 3 | -0.0489094 |
| MYO1E | myosin IE | -0.0477248 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0474228 |
| LMO7 | LIM domain 7 | -0.0469619 |
| RPL4 | ribosomal protein L4 | -0.0469001 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.046196 |
| CCPG1 | cell cycle progression 1 | -0.0460598 |
| RNF213 | ring finger protein 213 | -0.0456671 |
| RPL26 | ribosomal protein L26 | -0.0452997 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0446223 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0441668 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0409257 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0406548 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0403793 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0399265 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0398485 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.03973 |
| RPS12 | ribosomal protein S12 | -0.0392989 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0388515 |
| FOXP1 | forkhead box P1 | -0.0382964 |
| EXOC4 | exocyst complex component 4 | -0.0382309 |
| SQSTM1 | sequestosome 1 | -0.0382095 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0377667 |
| RPS3 | ribosomal protein S3 | -0.0375271 |
| RPS27A | ribosomal protein S27a | -0.0369539 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0367756 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0361356 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0354152 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0348958 |
| AGR2 | anterior gradient 2 | -0.0347533 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0344978 |
| GOLGB1 | golgin B1 | -0.0342744 |
| RPS19 | ribosomal protein S19 | -0.033504 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0328526 |
| RPL34 | ribosomal protein L34 | -0.0324712 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0323669 |
| PHF3 | PHD finger protein 3 | -0.0323649 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0320661 |
| WWOX | WW domain containing oxidoreductase | -0.0318051 |
| RPS25 | ribosomal protein S25 | -0.0318007 |
| RPS16 | ribosomal protein S16 | -0.0314866 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0313078 |
| HDLBP | high density lipoprotein binding protein | -0.0311402 |
| RPL38 | ribosomal protein L38 | -0.0311264 |
| ETV6 | ets variant 6 | -0.0309742 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0307076 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0303722 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0294019 |
| MX1 | MX dynamin-like GTPase 1 | -0.0293442 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0292087 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0291714 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0288169 |
| NDRG1 | N-myc downstream regulated 1 | -0.028365 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0282546 |
| RPS23 | ribosomal protein S23 | -0.0278879 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0273768 |
| MYO9A | myosin IXA | -0.0271948 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0268394 |
| RPL12 | ribosomal protein L12 | -0.0266272 |
| RPL7 | ribosomal protein L7 | -0.0265344 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0265036 |
| RIGI | RNA sensor RIG-I | -0.0264849 |
| NEBL | nebulette | -0.0264555 |
| RPL23 | ribosomal protein L23 | -0.0264554 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0263974 |
| RPS20 | ribosomal protein S20 | -0.0262692 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0261849 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0261843 |
| CCND2 | cyclin D2 | -0.0261349 |
| RPL19 | ribosomal protein L19 | -0.0261299 |
| GOLM2 | golgi membrane protein 2 | -0.0260693 |
| PGK1 | phosphoglycerate kinase 1 | -0.0260087 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0258232 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.025705 |
| RRBP1 | ribosome binding protein 1 | -0.0256554 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0254782 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0254082 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0253152 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0253088 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.025231 |
| MAP4 | microtubule-associated protein 4 | -0.0251607 |
