| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.211805 |
| SPAG9 | sperm associated antigen 9 | 0.108939 |
| TOP1 | topoisomerase (DNA) I | 0.0858542 |
| EGR1 | early growth response 1 | 0.0742197 |
| MCL1 | myeloid cell leukemia 1 | 0.0681153 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0632698 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0630622 |
| CCNL1 | cyclin L1 | 0.056073 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0525682 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.052425 |
| UVRAG | UV radiation resistance associated | 0.0517956 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0504522 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0495219 |
| INTS6 | integrator complex subunit 6 | 0.0488836 |
| SQSTM1 | sequestosome 1 | 0.0467343 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0463179 |
| USP36 | ubiquitin specific peptidase 36 | 0.0441064 |
| DENND4A | DENN/MADD domain containing 4A | 0.0436219 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0413716 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0394143 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0393333 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0381794 |
| HOMER1 | homer scaffolding protein 1 | 0.0370628 |
| JMJD1C | jumonji domain containing 1C | 0.0361306 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0359692 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0356238 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0350588 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0327658 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0316439 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0313331 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0304954 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0286577 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0277071 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.027464 |
| HBP1 | HMG-box transcription factor 1 | 0.0273871 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0271297 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0267563 |
| PER1 | period circadian clock 1 | 0.026276 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0252545 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0246154 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0241504 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0240809 |
| UBC | ubiquitin C | 0.0240528 |
| BRD2 | bromodomain containing 2 | 0.0237152 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0233905 |
| GPHN | gephyrin | 0.0233021 |
| PTMA | prothymosin, alpha | 0.02303 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0228731 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0228065 |
| RLF | rearranged L-myc fusion | 0.0228003 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0227492 |
| AFTPH | aftiphilin | 0.0223936 |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.0223027 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0220778 |
| USP34 | ubiquitin specific peptidase 34 | 0.0216717 |
| VMP1 | vacuole membrane protein 1 | 0.0210339 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0209802 |
| PCBP2 | poly(rC) binding protein 2 | 0.0209215 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0206975 |
| RPL31 | ribosomal protein L31 | 0.0204098 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0203222 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0201477 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0198259 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.019761 |
| RPL37A | ribosomal protein L37a | 0.0195273 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0194334 |
| MAP7 | microtubule-associated protein 7 | 0.0194066 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0190786 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.019069 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0190253 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0190027 |
| HELZ | helicase with zinc finger | 0.0187258 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0186085 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0183087 |
| PAPOLA | poly(A) polymerase alpha | 0.0183047 |
| H1-0 | H1.0 linker histone | 0.0182379 |
| SNX9 | sorting nexin 9 | 0.0181979 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0181767 |
| KIAA1217 | KIAA1217 | 0.018138 |
| NDRG1 | N-myc downstream regulated 1 | 0.0179918 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0178039 |
| GPATCH2L | G patch domain containing 2-like | 0.0172787 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0171555 |
| FDPS | farnesyl diphosphate synthase | 0.0170083 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0169431 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0169415 |
| MORF4L2 | mortality factor 4 like 2 | 0.0168306 |
| ANXA1 | annexin A1 | 0.0166503 |
| RBM39 | RNA binding motif protein 39 | 0.0166281 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0166157 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0166026 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0165908 |
| JUN | jun proto-oncogene | 0.0165336 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0164159 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0163875 |
| ATP13A3 | ATPase type 13A3 | 0.0163793 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0163274 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0162623 |
| RPS8 | ribosomal protein S8 | 0.0161629 |
| NABP1 | nucleic acid binding protein 1 | 0.0160908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.220713 |
| TXNRD1 | thioredoxin reductase 1 | -0.193742 |
| ASPH | aspartate beta-hydroxylase | -0.155202 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.154366 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0946342 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0898513 |
| MT2A | metallothionein 2A | -0.0856672 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0758545 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0693935 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0667651 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0618516 |
| EFNA5 | ephrin-A5 | -0.0559879 |
| LMO7 | LIM domain 7 | -0.0558948 |
| FAM13A | family with sequence similarity 13, member A | -0.0552234 |
| AHNAK | AHNAK nucleoprotein | -0.0546229 |
| TMSB10 | thymosin beta 10 | -0.0487517 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0478313 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0438624 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0436541 |
| SLTM | SAFB-like, transcription modulator | -0.0435918 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0423263 |
| CDCP1 | CUB domain containing protein 1 | -0.0413918 |
| OSMR | oncostatin M receptor | -0.0413341 |
| LAMA4 | laminin, alpha 4 | -0.0404894 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0387168 |
| NGLY1 | N-glycanase 1 | -0.0386159 |
| SMAD3 | SMAD family member 3 | -0.037263 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.036984 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0369484 |
| HDLBP | high density lipoprotein binding protein | -0.0364174 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0361961 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.035877 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.035394 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0349761 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0339348 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0336847 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0329148 |
| S100A11 | S100 calcium binding protein A11 | -0.0326559 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0324534 |
| GRAMD1B | GRAM domain containing 1B | -0.0320529 |
| DSPP | dentin sialophosphoprotein | -0.0317769 |
| TMEM165 | transmembrane protein 165 | -0.0317084 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.031018 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0310145 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0306749 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0305373 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0304079 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0302113 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0300307 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0294024 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0291192 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0289482 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.028633 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0285183 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0283385 |
| SCEL | sciellin | -0.0282016 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0277031 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0275309 |
| CANX | calnexin | -0.0274217 |
| RAB10 | RAB10, member RAS oncogene family | -0.0274148 |
| SDC1 | syndecan 1 | -0.0264595 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0260608 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0259697 |
| FOXP1 | forkhead box P1 | -0.0259142 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0258098 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0257224 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0256258 |
| MYO1B | myosin IB | -0.0254112 |
| MYOF | myoferlin | -0.0253438 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0253247 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0250734 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0250308 |
| RNF213 | ring finger protein 213 | -0.0248035 |
| SMYD3 | SET and MYND domain containing 3 | -0.0246339 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0246226 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0244607 |
| FTL | ferritin, light polypeptide | -0.0244481 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0242022 |
| CCND1 | cyclin D1 | -0.0238872 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0236565 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0236384 |
| PRKCA | protein kinase C, alpha | -0.0232186 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0227088 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0224444 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0223933 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0223703 |
| KRT18 | keratin 18, type I | -0.0221617 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0218301 |
| SON | SON DNA binding protein | -0.0216983 |
| SBF2 | SET binding factor 2 | -0.0216759 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0209435 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0208811 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0205203 |
| S100A10 | S100 calcium binding protein A10 | -0.0201966 |
| TES | testin LIM domain protein | -0.0200718 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0199084 |
| FLNB | filamin B, beta | -0.019804 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0198005 |
| EHBP1 | EH domain binding protein 1 | -0.0196822 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.019482 |
