| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | 0.10003 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0949244 |
| STC1 | stanniocalcin 1 | 0.0915092 |
| CD44 | CD44 molecule (Indian blood group) | 0.0910108 |
| NRG1 | neuregulin 1 | 0.0836482 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0785786 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0751516 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0747254 |
| MTSS1 | metastasis suppressor 1 | 0.0652533 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0650923 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0647578 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0611695 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.060412 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0525689 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.052004 |
| IL1B | interleukin 1, beta | 0.0469948 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0459395 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0444472 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0437423 |
| DNER | delta/notch-like EGF repeat containing | 0.0416433 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0414018 |
| VRK2 | vaccinia related kinase 2 | 0.0402418 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0402004 |
| EREG | epiregulin | 0.0388977 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0386898 |
| FRMD4A | FERM domain containing 4A | 0.0370131 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0369031 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0366637 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0341129 |
| RND3 | Rho family GTPase 3 | 0.0336586 |
| FAM20C | family with sequence similarity 20, member C | 0.0333252 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0333036 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0329758 |
| GLCCI1 | glucocorticoid induced 1 | 0.0327945 |
| KYNU | kynureninase | 0.0327498 |
| VIM | vimentin | 0.0322672 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0318855 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0299798 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0299527 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0293359 |
| NUMB | numb homolog (Drosophila) | 0.0291989 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0285715 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0279235 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0277086 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0275173 |
| FDPS | farnesyl diphosphate synthase | 0.0266202 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0265037 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0260199 |
| ANXA10 | annexin A10 | 0.0259335 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0259319 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0254445 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0253388 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.025279 |
| FAM107B | family with sequence similarity 107, member B | 0.0249203 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0248735 |
| CALU | calumenin | 0.0248446 |
| SNX9 | sorting nexin 9 | 0.0239092 |
| PCNX4 | pecanex 4 | 0.0236323 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.023478 |
| PRRX1 | paired related homeobox 1 | 0.0232954 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0228753 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0226845 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0226404 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0226045 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0222691 |
| AADAC | arylacetamide deacetylase | 0.0219638 |
| PCNX1 | pecanex 1 | 0.0218757 |
| HAS2 | hyaluronan synthase 2 | 0.0218628 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0217948 |
| CCNY | cyclin Y | 0.0215613 |
| CP | ceruloplasmin (ferroxidase) | 0.0214935 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0212603 |
| DENND4A | DENN/MADD domain containing 4A | 0.0211014 |
| GATA6 | GATA binding protein 6 | 0.0210838 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0209928 |
| LOX | lysyl oxidase | 0.020955 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0207944 |
| NAV3 | neuron navigator 3 | 0.0206012 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0205931 |
| TNS3 | tensin 3 | 0.0205082 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0203886 |
| COL12A1 | collagen, type XII, alpha 1 | 0.0202907 |
| HPCAL1 | hippocalcin-like 1 | 0.0202288 |
| DIAPH1 | diaphanous-related formin 1 | 0.020018 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0197968 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0196367 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0196336 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0191925 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0191548 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0191132 |
| PAPOLA | poly(A) polymerase alpha | 0.0190903 |
| LRRC8D | leucine rich repeat containing 8 family, member D | 0.0188453 |
| DCN | decorin | 0.0187374 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0186907 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.0183709 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0183622 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0183312 |
| RNF19B | ring finger protein 19B | 0.0182331 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | 0.0181668 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0181411 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.133972 |
| GPC6 | glypican 6 | -0.112466 |
| RAD51B | RAD51 paralog B | -0.107782 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0959222 |
| PRELID2 | PRELI domain containing 2 | -0.089489 |
| PCBP2 | poly(rC) binding protein 2 | -0.0881961 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0801913 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0748719 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0748288 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0726627 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0698791 |
| FN1 | fibronectin 1 | -0.067069 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0646773 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0616975 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0611718 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0597303 |
| FTL | ferritin, light polypeptide | -0.0594625 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.058815 |
| DST | dystonin | -0.0580601 |
| MAP1B | microtubule-associated protein 1B | -0.054963 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0547069 |
| USP34 | ubiquitin specific peptidase 34 | -0.0540847 |
| NDRG1 | N-myc downstream regulated 1 | -0.0509095 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0501614 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0478237 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0467819 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.046559 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0465069 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0448903 |
| RUNX1 | runt-related transcription factor 1 | -0.0436971 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0429902 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0427367 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0424324 |
| SYT1 | synaptotagmin I | -0.0418157 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0417276 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0403844 |
| FAM13A | family with sequence similarity 13, member A | -0.040169 |
| CA12 | carbonic anhydrase XII | -0.0401438 |
| SUMF1 | sulfatase modifying factor 1 | -0.0401283 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0394038 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0389032 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0380939 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0379289 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.037668 |
| ASPH | aspartate beta-hydroxylase | -0.0374453 |
| ETV6 | ets variant 6 | -0.037347 |
| MYOF | myoferlin | -0.0372315 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0372171 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0367337 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0363605 |
| HMGA1 | high mobility group AT-hook 1 | -0.0361839 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0355815 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.035424 |
| TMSB10 | thymosin beta 10 | -0.0352795 |
| PRKCA | protein kinase C, alpha | -0.0345644 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0343724 |
| ZNF292 | zinc finger protein 292 | -0.034213 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0341519 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0337284 |
| OGA | O-GlcNAcase | -0.0330342 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.032951 |
| TNNC1 | troponin C type 1 (slow) | -0.0327869 |
| PFKP | phosphofructokinase, platelet | -0.0318694 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0317321 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0316364 |
| RPS19 | ribosomal protein S19 | -0.0314314 |
| PHF21A | PHD finger protein 21A | -0.0308601 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0308182 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0307602 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0305824 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0304393 |
| TXNIP | thioredoxin interacting protein | -0.0304359 |
| EGR1 | early growth response 1 | -0.0301519 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0291447 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.029105 |
| HDAC4 | histone deacetylase 4 | -0.0290284 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0289834 |
| HMGA2 | high mobility group AT-hook 2 | -0.0289269 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0288046 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.028498 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0284178 |
| FLNB | filamin B, beta | -0.0277482 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0273864 |
| EGFR | epidermal growth factor receptor | -0.0273483 |
| MSI2 | musashi RNA-binding protein 2 | -0.0273443 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0272607 |
| SBF2 | SET binding factor 2 | -0.0270042 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0270028 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0269282 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0268391 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0267636 |
| EXOC6B | exocyst complex component 6B | -0.0267372 |
| RAB7A | RAB7A, member RAS oncogene family | -0.026666 |
| FRYL | FRY-like | -0.026396 |
| SYNJ2 | synaptojanin 2 | -0.0263025 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0261992 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.025943 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0258368 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.025754 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0256961 |
