| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.115194 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0851012 |
| VIM | vimentin | 0.0845166 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0757632 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0713717 |
| MCL1 | myeloid cell leukemia 1 | 0.0689112 |
| IGF2 | insulin-like growth factor 2 | 0.0656525 |
| EGR1 | early growth response 1 | 0.0581288 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0478233 |
| PYGL | phosphorylase, glycogen, liver | 0.0452371 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0429368 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0422737 |
| CMIP | c-Maf inducing protein | 0.0404494 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0377274 |
| ACTG1 | actin gamma 1 | 0.0373063 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0370634 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0359109 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0335218 |
| LDHA | lactate dehydrogenase A | 0.0322248 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0318581 |
| COPA | coatomer protein complex, subunit alpha | 0.0310794 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0309874 |
| TPM4 | tropomyosin 4 | 0.0306109 |
| ANGPTL4 | angiopoietin-like 4 | 0.0284164 |
| HLA-B | major histocompatibility complex, class I, B | 0.0277038 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0275534 |
| PFN1 | profilin 1 | 0.0273407 |
| FLNB | filamin B, beta | 0.0271015 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0269742 |
| POTEF | POTE ankyrin domain family, member F | 0.0268205 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0263457 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0259306 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0258319 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0257793 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0254315 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0247757 |
| THBS1 | thrombospondin 1 | 0.0246845 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0244164 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0240135 |
| IL6 | interleukin 6 | 0.0237138 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0235763 |
| TMSB10 | thymosin beta 10 | 0.0227205 |
| HLA-A | major histocompatibility complex, class I, A | 0.0220868 |
| NAV3 | neuron navigator 3 | 0.0215338 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0211704 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0210277 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0199045 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0196101 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0195326 |
| INHBA | inhibin, beta A | 0.0194878 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0193155 |
| S100A6 | S100 calcium binding protein A6 | 0.0192649 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.019264 |
| TMEM87A | transmembrane protein 87A | 0.018968 |
| ADM | adrenomedullin | 0.0178765 |
| INO80 | INO80 complex subunit | 0.0178502 |
| EGFR | epidermal growth factor receptor | 0.0177509 |
| PTK2 | protein tyrosine kinase 2 | 0.0177148 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0174777 |
| OSMR | oncostatin M receptor | 0.017339 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0172711 |
| AK1 | adenylate kinase 1 | 0.0171112 |
| NF1 | neurofibromin 1 | 0.0170781 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0168581 |
| KYNU | kynureninase | 0.0167934 |
| ACTN1 | actinin, alpha 1 | 0.016757 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0166644 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0162893 |
| RASAL2 | RAS protein activator like 2 | 0.0160159 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0158468 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.0154138 |
| LAMC2 | laminin, gamma 2 | 0.0152276 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0152152 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0152017 |
| MYO1E | myosin IE | 0.0151107 |
| MOK | MOK protein kinase | 0.0150113 |
| USP36 | ubiquitin specific peptidase 36 | 0.0149815 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.0149705 |
| BRD2 | bromodomain containing 2 | 0.0148317 |
| TAGLN2 | transgelin 2 | 0.0145664 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0144349 |
| HMGA2 | high mobility group AT-hook 2 | 0.0142912 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0139509 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0138802 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.013857 |
| MYADM | myeloid-associated differentiation marker | 0.0136397 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0135103 |
| TGM2 | transglutaminase 2 | 0.0135101 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0134675 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0134118 |
| SLC35F3 | solute carrier family 35, member F3 | 0.013354 |
| MT2A | metallothionein 2A | 0.0132691 |
| CSNK1E | casein kinase 1, epsilon | 0.0130702 |
| JUP | junction plakoglobin | 0.012924 |
| RHOA | ras homolog family member A | 0.0129208 |
| PCED1B | PC-esterase domain containing 1B | 0.012856 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0125386 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0125043 |
| VMP1 | vacuole membrane protein 1 | 0.0124517 |
| CD99 | CD99 molecule | 0.0124252 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | -0.209072 |
| GRAMD1B | GRAM domain containing 1B | -0.177923 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.142185 |
| TXNRD1 | thioredoxin reductase 1 | -0.107471 |
| FTL | ferritin, light polypeptide | -0.100522 |
| RPS2 | ribosomal protein S2 | -0.0889361 |
| RPL19 | ribosomal protein L19 | -0.0882278 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.075463 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0743549 |
| RPS12 | ribosomal protein S12 | -0.0705876 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0626339 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0588204 |
| ASPH | aspartate beta-hydroxylase | -0.0586752 |
| PTMA | prothymosin, alpha | -0.0583974 |
| RPL23 | ribosomal protein L23 | -0.0577572 |
| WWOX | WW domain containing oxidoreductase | -0.0570368 |
| TPM3 | tropomyosin 3 | -0.0559761 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0555112 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0528711 |
| RTN4 | reticulon 4 | -0.0528292 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0522824 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0511167 |
| RPL7 | ribosomal protein L7 | -0.0510542 |
| RPLP1 | ribosomal protein, large, P1 | -0.0489761 |
| FGB | fibrinogen beta chain | -0.0487472 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0486229 |
| PFDN2 | prefoldin subunit 2 | -0.0484987 |
| KIF5B | kinesin family member 5B | -0.0481901 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0477267 |
| YBX3 | Y box binding protein 3 | -0.0456468 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0428712 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.042134 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0414068 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0410862 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.040819 |
| TPD52 | tumor protein D52 | -0.040657 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0403825 |
| RPS8 | ribosomal protein S8 | -0.0390594 |
| RPS27A | ribosomal protein S27a | -0.0382752 |
| RPS25 | ribosomal protein S25 | -0.0374001 |
| RPL4 | ribosomal protein L4 | -0.037069 |
| TNPO1 | transportin 1 | -0.0368635 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0368351 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0356125 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0355219 |
| RPL36 | ribosomal protein L36 | -0.0351812 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0349569 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0348551 |
| MATR3 | matrin 3 | -0.0345811 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0345096 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0342807 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0341757 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0341632 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0338357 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.03382 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0336731 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0336591 |
| RPL26 | ribosomal protein L26 | -0.0335495 |
| NCKAP1 | NCK-associated protein 1 | -0.0328654 |
| RPL37A | ribosomal protein L37a | -0.032605 |
| RPS6 | ribosomal protein S6 | -0.0317995 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0314922 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0308088 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0307109 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0306646 |
| AHR | aryl hydrocarbon receptor | -0.0305967 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0302124 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.029878 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.029639 |
| CLTC | clathrin, heavy chain (Hc) | -0.0295801 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0295266 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0290083 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0289148 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0287664 |
| RPS19 | ribosomal protein S19 | -0.0283504 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0283325 |
| RNF145 | ring finger protein 145 | -0.0282693 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.028113 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0276061 |
| RPL12 | ribosomal protein L12 | -0.0275094 |
| XPO1 | exportin 1 | -0.0269522 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0268696 |
| PDE8A | phosphodiesterase 8A | -0.0265894 |
| RBM39 | RNA binding motif protein 39 | -0.0262864 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0262568 |
| RPL37 | ribosomal protein L37 | -0.0261501 |
| RPS17 | ribosomal protein S17 | -0.0260434 |
| RPS21 | ribosomal protein S21 | -0.0259993 |
| CANX | calnexin | -0.0259887 |
| RPS3 | ribosomal protein S3 | -0.0259851 |
| RPS20 | ribosomal protein S20 | -0.0259078 |
| RPL5 | ribosomal protein L5 | -0.0258015 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0256892 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0256696 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0253828 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0253724 |
| PHF3 | PHD finger protein 3 | -0.0245408 |
| CCNY | cyclin Y | -0.0245236 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0245055 |
| HSPA4 | heat shock 70kDa protein 4 | -0.0244922 |
