| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT17 | keratin 17, type I | 0.117622 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.109832 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0994891 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0890727 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0829271 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0817877 |
| TXNRD1 | thioredoxin reductase 1 | 0.0763832 |
| RND3 | Rho family GTPase 3 | 0.076239 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0674094 |
| NDRG1 | N-myc downstream regulated 1 | 0.0577713 |
| FTL | ferritin, light polypeptide | 0.056811 |
| SPAG9 | sperm associated antigen 9 | 0.0537783 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0535004 |
| OXSR1 | oxidative stress responsive 1 | 0.0526817 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0518155 |
| FN1 | fibronectin 1 | 0.0505769 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0499302 |
| TUSC3 | tumor suppressor candidate 3 | 0.0482545 |
| SQSTM1 | sequestosome 1 | 0.0481726 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0464823 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0464021 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0456525 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0454452 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.043017 |
| B2M | beta-2-microglobulin | 0.0420477 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0418934 |
| MT2A | metallothionein 2A | 0.0418234 |
| STK17A | serine/threonine kinase 17a | 0.0403504 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0397956 |
| VIM | vimentin | 0.0391678 |
| TXNIP | thioredoxin interacting protein | 0.0388553 |
| EP300 | E1A binding protein p300 | 0.0377981 |
| GOLGA4 | golgin A4 | 0.0376908 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0373951 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0368276 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0368257 |
| STC1 | stanniocalcin 1 | 0.0366074 |
| KIF5B | kinesin family member 5B | 0.0362384 |
| FAM13A | family with sequence similarity 13, member A | 0.0360988 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0359629 |
| RORA | RAR-related orphan receptor A | 0.0347507 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0347105 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0344727 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0342753 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0340609 |
| TPD52 | tumor protein D52 | 0.0328938 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0325687 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.032229 |
| FMNL2 | formin-like 2 | 0.0317501 |
| PTK2 | protein tyrosine kinase 2 | 0.0315065 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0313065 |
| MXD1 | MAX dimerization protein 1 | 0.0312263 |
| GPC6 | glypican 6 | 0.0311858 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0311693 |
| GNAS | GNAS complex locus | 0.0311659 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0310098 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0306791 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0303798 |
| SRPK2 | SRSF protein kinase 2 | 0.0302563 |
| YTHDC1 | YTH domain containing 1 | 0.0298083 |
| RPS27A | ribosomal protein S27a | 0.0294854 |
| LDHA | lactate dehydrogenase A | 0.0290123 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0289424 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0289378 |
| XDH | xanthine dehydrogenase | 0.0289168 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0288516 |
| SEPTIN2 | septin 2 | 0.0287604 |
| S100P | S100 calcium binding protein P | 0.0284852 |
| KYNU | kynureninase | 0.0283902 |
| RUNX1 | runt-related transcription factor 1 | 0.028 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0279142 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0278856 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0278374 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.027836 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0275319 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0273848 |
| RNF24 | ring finger protein 24 | 0.0272432 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0271471 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0270619 |
| GOLGB1 | golgin B1 | 0.0269271 |
| FOSL1 | FOS-like antigen 1 | 0.0267707 |
| JMJD1C | jumonji domain containing 1C | 0.0265148 |
| KLF6 | Kruppel-like factor 6 | 0.0263261 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0263032 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0262593 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0261614 |
| CREBRF | CREB3 regulatory factor | 0.0261331 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0260957 |
| SDC4 | syndecan 4 | 0.0259915 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0259662 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0259104 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0259098 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0258888 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0255431 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0253203 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0252545 |
| DTNA | dystrobrevin, alpha | 0.025237 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0252317 |
| OSBP | oxysterol binding protein | 0.025092 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0250167 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.198087 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.128246 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.127033 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.123732 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0937066 |
| ATOSA | atos homolog A | -0.0886135 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.086915 |
| MUC16 | mucin 16, cell surface associated | -0.0845083 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0634066 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0629167 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0596859 |
| ASPH | aspartate beta-hydroxylase | -0.058046 |
| SVIL | supervillin | -0.056759 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0540103 |
| RBM47 | RNA binding motif protein 47 | -0.0510196 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0498424 |
| LAMC2 | laminin, gamma 2 | -0.0484698 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0483423 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0473804 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0464016 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0463327 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0463186 |
| EGFR | epidermal growth factor receptor | -0.0461778 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0459544 |
| MYO1E | myosin IE | -0.0447283 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0446694 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0437654 |
| ABHD17C | abhydrolase domain containing 17C | -0.0430705 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0421688 |
| OSMR | oncostatin M receptor | -0.0415223 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0414349 |
| TJP1 | tight junction protein 1 | -0.0409715 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0398354 |
| ZNF638 | zinc finger protein 638 | -0.0398277 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0378154 |
| CUX1 | cut-like homeobox 1 | -0.0367717 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0366551 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0358323 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0357446 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0352644 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0351481 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0345545 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0343835 |
| KIF13B | kinesin family member 13B | -0.0340694 |
| MEF2A | myocyte enhancer factor 2A | -0.0327352 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0323525 |
| NEBL | nebulette | -0.0316163 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0315286 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0314252 |
| TGFA | transforming growth factor, alpha | -0.0314113 |
| IGF2 | insulin-like growth factor 2 | -0.0310289 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0306903 |
| CNKSR3 | CNKSR family member 3 | -0.0305573 |
| TJP2 | tight junction protein 2 | -0.0304874 |
| ZNF292 | zinc finger protein 292 | -0.0304106 |
| MYO5C | myosin VC | -0.0303817 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0294638 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | -0.0291501 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0289208 |
| FOSL2 | FOS-like antigen 2 | -0.0287899 |
| PARD3 | par-3 family cell polarity regulator | -0.0279471 |
| PLSCR1 | phospholipid scramblase 1 | -0.0278026 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.027632 |
| TMEM165 | transmembrane protein 165 | -0.027261 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0266649 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0266568 |
| FBXO11 | F-box protein 11 | -0.0265736 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0265344 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0264675 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0263584 |
| PER1 | period circadian clock 1 | -0.0263033 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0262818 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0262781 |
| RAD51B | RAD51 paralog B | -0.0262049 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0260688 |
| HMGA2 | high mobility group AT-hook 2 | -0.0260205 |
| FOXP1 | forkhead box P1 | -0.0257366 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0251877 |
| PTMA | prothymosin, alpha | -0.0250516 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.025048 |
| TCF12 | transcription factor 12 | -0.0248146 |
| ETV6 | ets variant 6 | -0.0247775 |
| CLDN7 | claudin 7 | -0.0247679 |
| CDK14 | cyclin-dependent kinase 14 | -0.024516 |
| XPO1 | exportin 1 | -0.024155 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0241389 |
| RPL4 | ribosomal protein L4 | -0.0239484 |
| FAM107B | family with sequence similarity 107, member B | -0.0238357 |
| ATF6 | activating transcription factor 6 | -0.0232835 |
| NF1 | neurofibromin 1 | -0.0232549 |
| CD2AP | CD2-associated protein | -0.0229472 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0229251 |
| ACTN4 | actinin, alpha 4 | -0.0228119 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0227546 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0226593 |
| SERINC3 | serine incorporator 3 | -0.0226139 |
| ERBIN | erbb2 interacting protein | -0.0226063 |
| USP6NL | USP6 N-terminal like | -0.022593 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0225849 |
| PCNX1 | pecanex 1 | -0.0225631 |
