| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0963776 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.051849 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0475301 |
| CCNL1 | cyclin L1 | 0.0435411 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0399375 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0390921 |
| TPM3 | tropomyosin 3 | 0.0389174 |
| RTN4 | reticulon 4 | 0.0379218 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0360961 |
| TXNRD1 | thioredoxin reductase 1 | 0.0359789 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0330755 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0329648 |
| SPAG9 | sperm associated antigen 9 | 0.0323085 |
| BRD2 | bromodomain containing 2 | 0.0323068 |
| PCBP2 | poly(rC) binding protein 2 | 0.0319657 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0303578 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0296493 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0296438 |
| ANXA5 | annexin A5 | 0.0290864 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285479 |
| ANLN | anillin, actin binding protein | 0.027231 |
| NUP153 | nucleoporin 153kDa | 0.0267963 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0263072 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0260022 |
| CRY1 | cryptochrome circadian clock 1 | 0.0259414 |
| JMJD1C | jumonji domain containing 1C | 0.0256853 |
| MCL1 | myeloid cell leukemia 1 | 0.0255109 |
| SRPK1 | SRSF protein kinase 1 | 0.0250327 |
| NUP58 | nucleoporin 58 | 0.0249564 |
| DIAPH3 | diaphanous-related formin 3 | 0.0249228 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0248886 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0247545 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.024752 |
| PNN | pinin, desmosome associated protein | 0.0246333 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0243647 |
| ATL2 | atlastin GTPase 2 | 0.0239157 |
| PER1 | period circadian clock 1 | 0.0238019 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0236179 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0233224 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0231632 |
| OGA | O-GlcNAcase | 0.0230828 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0230778 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0230551 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0222948 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0222298 |
| IPO7 | importin 7 | 0.022123 |
| TFG | TRK-fused gene | 0.0220261 |
| TPX2 | TPX2, microtubule-associated | 0.0215904 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0212921 |
| RBM25 | RNA binding motif protein 25 | 0.0212803 |
| NOTCH2 | notch 2 | 0.0212561 |
| RBM39 | RNA binding motif protein 39 | 0.0211857 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0210654 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0209952 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0209557 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0207605 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0203994 |
| PHIP | pleckstrin homology domain interacting protein | 0.020366 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.020313 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.020202 |
| NCKAP1 | NCK-associated protein 1 | 0.0201177 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0199724 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0199315 |
| FNIP1 | folliculin interacting protein 1 | 0.0199267 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0199216 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0197117 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0196877 |
| WAC | WW domain containing adaptor with coiled-coil | 0.01951 |
| RNF145 | ring finger protein 145 | 0.0193956 |
| SLMAP | sarcolemma associated protein | 0.0192919 |
| CKAP5 | cytoskeleton associated protein 5 | 0.019255 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0190183 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0187647 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0187134 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0185623 |
| RPL3 | ribosomal protein L3 | 0.0183897 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0183782 |
| DIAPH1 | diaphanous-related formin 1 | 0.018228 |
| TBK1 | TANK-binding kinase 1 | 0.0182206 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0177817 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0177796 |
| PCNX1 | pecanex 1 | 0.0177111 |
| MELK | maternal embryonic leucine zipper kinase | 0.0176212 |
| RRM2 | ribonucleotide reductase M2 | 0.0175592 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0175482 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0175021 |
| STIL | SCL/TAL1 interrupting locus | 0.0174477 |
| PTEN | phosphatase and tensin homolog | 0.017445 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0173911 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.017283 |
| OLA1 | Obg-like ATPase 1 | 0.0170917 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0170598 |
| CEP95 | centrosomal protein 95kDa | 0.0170145 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0169969 |
| SPAG5 | sperm associated antigen 5 | 0.0169762 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0169747 |
| THOC1 | THO complex 1 | 0.0169598 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0168947 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0168815 |
| TNPO3 | transportin 3 | 0.0167644 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.291044 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.209167 |
| TMSB10 | thymosin beta 10 | -0.112118 |
| VIM | vimentin | -0.0919888 |
| PTMA | prothymosin, alpha | -0.0856226 |
| RAD51B | RAD51 paralog B | -0.0762127 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0729066 |
| YBX3 | Y box binding protein 3 | -0.0680465 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0669797 |
| RPS3 | ribosomal protein S3 | -0.0589277 |
| RPL35A | ribosomal protein L35a | -0.0554122 |
| RPS8 | ribosomal protein S8 | -0.0552779 |
| ACTG1 | actin gamma 1 | -0.054507 |
| GRAMD1B | GRAM domain containing 1B | -0.0527007 |
| AHNAK | AHNAK nucleoprotein | -0.0521402 |
| RPL37 | ribosomal protein L37 | -0.0517809 |
| RPS21 | ribosomal protein S21 | -0.0515884 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.051558 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.051056 |
| MT2A | metallothionein 2A | -0.0505919 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0498534 |
| CAVIN1 | caveolae associated protein 1 | -0.0493563 |
| RPLP1 | ribosomal protein, large, P1 | -0.0478885 |
| FTL | ferritin, light polypeptide | -0.0472602 |
| EXOC4 | exocyst complex component 4 | -0.0467333 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0455845 |
| RPL23 | ribosomal protein L23 | -0.0455324 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0454708 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0430091 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0426292 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0412003 |
| RPS19 | ribosomal protein S19 | -0.0407853 |
| RPL19 | ribosomal protein L19 | -0.0401408 |
| RPS29 | ribosomal protein S29 | -0.0400887 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0396712 |
| RPLP0 | ribosomal protein, large, P0 | -0.0390693 |
| RPS27A | ribosomal protein S27a | -0.0388926 |
| RPL26 | ribosomal protein L26 | -0.0375194 |
| HMGA2 | high mobility group AT-hook 2 | -0.0365119 |
| RPS27 | ribosomal protein S27 | -0.0360146 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0355094 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0349819 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0344085 |
| RPL36 | ribosomal protein L36 | -0.0341717 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0341631 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0336855 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0336523 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0330108 |
| RPL34 | ribosomal protein L34 | -0.0328403 |
| RPL38 | ribosomal protein L38 | -0.0327273 |
| RPL31 | ribosomal protein L31 | -0.0325844 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0323613 |
| RPS10 | ribosomal protein S10 | -0.0321219 |
| CUX1 | cut-like homeobox 1 | -0.0321186 |
| GNAS | GNAS complex locus | -0.031758 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0316522 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0311218 |
| RPL32 | ribosomal protein L32 | -0.0306932 |
| HLA-B | major histocompatibility complex, class I, B | -0.0304902 |
| ATXN1 | ataxin 1 | -0.0296938 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0296111 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0295024 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0294111 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0293537 |
| RPL12 | ribosomal protein L12 | -0.029127 |
| RPS15 | ribosomal protein S15 | -0.0289643 |
| RPL8 | ribosomal protein L8 | -0.0289238 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0284084 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0283835 |
| RPLP2 | ribosomal protein, large, P2 | -0.0283639 |
| RNF213 | ring finger protein 213 | -0.0283337 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0279241 |
| TPI1 | triosephosphate isomerase 1 | -0.0276592 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0274135 |
| RPL11 | ribosomal protein L11 | -0.026864 |
| EHBP1 | EH domain binding protein 1 | -0.0268277 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0267828 |
| RPS24 | ribosomal protein S24 | -0.0267423 |
| TPM4 | tropomyosin 4 | -0.0266653 |
| BPTF | bromodomain PHD finger transcription factor | -0.0265111 |
| S100A10 | S100 calcium binding protein A10 | -0.0264489 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0262953 |
| OSMR | oncostatin M receptor | -0.0262808 |
| KRT18 | keratin 18, type I | -0.0262181 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.026067 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0258098 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0257969 |
| RPL36A | ribosomal protein L36a | -0.0257002 |
| RACK1 | receptor for activated C kinase 1 | -0.025439 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0254246 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0249442 |
| KLF6 | Kruppel-like factor 6 | -0.0249318 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0246003 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0241726 |
| PYGL | phosphorylase, glycogen, liver | -0.0241089 |
| FMNL2 | formin-like 2 | -0.0239872 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.023921 |
| GOLGB1 | golgin B1 | -0.0235597 |
| EGFR | epidermal growth factor receptor | -0.0232438 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0231382 |
