| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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195 genes differentially expressed following the Ouabain (Octahydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.213104 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0911344 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0817845 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0807681 |
| CUL3 | cullin 3 | 0.0765949 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0720886 |
| NCKAP1 | NCK-associated protein 1 | 0.0709257 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0648476 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0647295 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0629836 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0569734 |
| FNIP1 | folliculin interacting protein 1 | 0.0565849 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0564761 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0552618 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0550968 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0549367 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0549107 |
| INTS6 | integrator complex subunit 6 | 0.0543564 |
| EGR1 | early growth response 1 | 0.0540254 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0523224 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0523084 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0516508 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0493346 |
| RBM33 | RNA binding motif protein 33 | 0.0483008 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0472501 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0466861 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0455739 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0451734 |
| YME1L1 | YME1-like 1 ATPase | 0.0439258 |
| LDHA | lactate dehydrogenase A | 0.0438472 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0432481 |
| MATR3 | matrin 3 | 0.0418882 |
| TLK1 | tousled-like kinase 1 | 0.0403121 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0397948 |
| ZNF207 | zinc finger protein 207 | 0.0397923 |
| PTGES2 | prostaglandin E synthase 2 | 0.0386639 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0384576 |
| MEMO1 | mediator of cell motility 1 | 0.0378773 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0372613 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.037238 |
| RBM39 | RNA binding motif protein 39 | 0.0366944 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0365552 |
| MCL1 | myeloid cell leukemia 1 | 0.036248 |
| MED13 | mediator complex subunit 13 | 0.0361611 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.034698 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0342507 |
| RLF | rearranged L-myc fusion | 0.0333677 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0332619 |
| TRIM33 | tripartite motif containing 33 | 0.0331033 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0329192 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.03285 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0325663 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0321294 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0320992 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0317038 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0315358 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0314456 |
| ZNF292 | zinc finger protein 292 | 0.0310033 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0309617 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0293338 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0292435 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0282094 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.028029 |
| TXNIP | thioredoxin interacting protein | 0.0276888 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0269105 |
| RPS12 | ribosomal protein S12 | 0.0268797 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.026402 |
| PKN2 | protein kinase N2 | 0.0250391 |
| WDR43 | WD repeat domain 43 | 0.0223966 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0209019 |
| JMJD1C | jumonji domain containing 1C | 0.0205039 |
| EZR | ezrin | 0.0200048 |
| SLTM | SAFB-like, transcription modulator | 0.0197777 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0186162 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0179919 |
| RPS6 | ribosomal protein S6 | 0.0168552 |
| PCBP2 | poly(rC) binding protein 2 | 0.016719 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.015699 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0153549 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0152047 |
| JUN | jun proto-oncogene | 0.0145647 |
| TFRC | transferrin receptor | 0.0140876 |
| PARD3 | par-3 family cell polarity regulator | 0.0127315 |
| CCNL1 | cyclin L1 | 0.0124204 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0118022 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0116421 |
| PTMA | prothymosin, alpha | 0.01142 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0111589 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0107643 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0105595 |
| MED13L | mediator complex subunit 13-like | 0.00896128 |
| NF1 | neurofibromin 1 | 0.00867877 |
| RBM25 | RNA binding motif protein 25 | 0.00796025 |
| OGA | O-GlcNAcase | 0.00647643 |
| PGK1 | phosphoglycerate kinase 1 | 0.00623351 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00606518 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00501874 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00488753 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00380881 |
| USP34 | ubiquitin specific peptidase 34 | 0.00335369 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146133 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.136858 |
| VIM | vimentin | -0.120524 |
| NDRG1 | N-myc downstream regulated 1 | -0.100878 |
| FN1 | fibronectin 1 | -0.0836621 |
| EGFR | epidermal growth factor receptor | -0.0751664 |
| FTL | ferritin, light polypeptide | -0.0697322 |
| MT2A | metallothionein 2A | -0.0693129 |
| PKM | pyruvate kinase, muscle | -0.0693121 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0634312 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0585861 |
| ANXA2 | annexin A2 | -0.0570282 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0567224 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0566341 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0561879 |
| ASPH | aspartate beta-hydroxylase | -0.0548828 |
| RPL11 | ribosomal protein L11 | -0.054101 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0514022 |
| RPL37 | ribosomal protein L37 | -0.0473708 |
| RPS16 | ribosomal protein S16 | -0.0451592 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0448951 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.044066 |
| SMYD3 | SET and MYND domain containing 3 | -0.0435346 |
| SYT1 | synaptotagmin I | -0.0429197 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0417575 |
| RPL12 | ribosomal protein L12 | -0.0414366 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0408788 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0407957 |
| RACK1 | receptor for activated C kinase 1 | -0.040634 |
| ATP13A3 | ATPase type 13A3 | -0.0402811 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0397639 |
| CALR | calreticulin | -0.038555 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0383306 |
| MORF4L2 | mortality factor 4 like 2 | -0.037758 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0375023 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0368738 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0366886 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0359713 |
| GPC6 | glypican 6 | -0.0353185 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0332174 |
| RPLP0 | ribosomal protein, large, P0 | -0.0331915 |
| STC1 | stanniocalcin 1 | -0.0331606 |
| TMSB10 | thymosin beta 10 | -0.0330499 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.033036 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0328829 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0328057 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0306326 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0306013 |
| RUNX1 | runt-related transcription factor 1 | -0.0300763 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0296342 |
| HDLBP | high density lipoprotein binding protein | -0.0295484 |
| ADM | adrenomedullin | -0.028889 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0284894 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0284414 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0279166 |
| TSC22D2 | TSC22 domain family, member 2 | -0.026278 |
| GOLGA4 | golgin A4 | -0.0260132 |
| FAM13A | family with sequence similarity 13, member A | -0.025811 |
| B2M | beta-2-microglobulin | -0.025748 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0252601 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0249402 |
| TXNRD1 | thioredoxin reductase 1 | -0.0238721 |
| HLA-B | major histocompatibility complex, class I, B | -0.0237351 |
| KIF5B | kinesin family member 5B | -0.023697 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0227651 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.022043 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0219849 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0207355 |
| RPL35A | ribosomal protein L35a | -0.0198529 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.019592 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0194998 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0191043 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0186987 |
| CANX | calnexin | -0.0184898 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0177747 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0164452 |
| RPLP2 | ribosomal protein, large, P2 | -0.01636 |
| PTK2 | protein tyrosine kinase 2 | -0.0150366 |
| SPAG9 | sperm associated antigen 9 | -0.0139994 |
| RPL26 | ribosomal protein L26 | -0.0124492 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0112448 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0111768 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0109011 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0100633 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0091393 |
| ITGA6 | integrin, alpha 6 | -0.00873411 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00772333 |
| GNAS | GNAS complex locus | -0.00661711 |
| GPHN | gephyrin | -0.00382077 |
| SETD5 | SET domain containing 5 | -0.00242029 |
| RTN4 | reticulon 4 | -0.00203336 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | -0.00199843 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -8.80328E-4 |
| KTN1 | kinectin 1 (kinesin receptor) | -6.27201E-4 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -5.16619E-4 |
