| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.114339 |
| HDAC9 | histone deacetylase 9 | 0.0662447 |
| NCKAP1 | NCK-associated protein 1 | 0.0581042 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0475987 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0455855 |
| OGA | O-GlcNAcase | 0.0451929 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0448937 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0446114 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0439122 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0417365 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.041565 |
| BRD2 | bromodomain containing 2 | 0.0389677 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0374992 |
| TFRC | transferrin receptor | 0.0367537 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0348825 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.034771 |
| WDR43 | WD repeat domain 43 | 0.0343499 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0341462 |
| PAPOLA | poly(A) polymerase alpha | 0.0337447 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0329398 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.03259 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0312672 |
| H1-0 | H1.0 linker histone | 0.030869 |
| NPR2 | natriuretic peptide receptor 2 | 0.0306014 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0302715 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | 0.0301764 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0301102 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0298811 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0294333 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0293666 |
| COLEC11 | collectin sub-family member 11 | 0.0290746 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0290129 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0289205 |
| JMJD1C | jumonji domain containing 1C | 0.0288644 |
| RHEB | Ras homolog enriched in brain | 0.0285973 |
| USP25 | ubiquitin specific peptidase 25 | 0.0285776 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0285394 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0280621 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0280222 |
| KIF5B | kinesin family member 5B | 0.0276847 |
| NUP153 | nucleoporin 153kDa | 0.027208 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0272034 |
| SRP54 | signal recognition particle 54kDa | 0.027006 |
| CDC73 | cell division cycle 73 | 0.0264052 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0262557 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0261242 |
| PSPC1 | paraspeckle component 1 | 0.0260641 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0257235 |
| AZIN1 | antizyme inhibitor 1 | 0.0252627 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.024993 |
| SIK3 | SIK family kinase 3 | 0.0249888 |
| NPTN | neuroplastin | 0.0241677 |
| ABI1 | abl-interactor 1 | 0.0239281 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0237876 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0236829 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0234296 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0233433 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233172 |
| CCNL1 | cyclin L1 | 0.0232852 |
| MED13L | mediator complex subunit 13-like | 0.0232126 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0228874 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0228698 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0228565 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0227924 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0227082 |
| MEF2C | myocyte enhancer factor 2C | 0.0226675 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0226653 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0223129 |
| ZNF217 | zinc finger protein 217 | 0.0221005 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | 0.02159 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0215444 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0215296 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0215193 |
| ABI2 | abl-interactor 2 | 0.0214974 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0214308 |
| CLTC | clathrin, heavy chain (Hc) | 0.0214271 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0214078 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0213472 |
| HBS1L | HBS1-like translational GTPase | 0.0213256 |
| RTTN | rotatin | 0.0211586 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0210397 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0208231 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0207517 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0207015 |
| ZFP36 | ZFP36 ring finger protein | 0.0206664 |
| FAM171B | family with sequence similarity 171, member B | 0.0204563 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0204133 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0203257 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | 0.0202344 |
| CDC14A | cell division cycle 14A | 0.0200534 |
| EP300 | E1A binding protein p300 | 0.0199703 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.0199152 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.019855 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0197727 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0196231 |
| XPO6 | exportin 6 | 0.0196176 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0195849 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0195522 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.019457 |
| USP15 | ubiquitin specific peptidase 15 | 0.0194237 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.163976 |
| COL11A1 | collagen, type XI, alpha 1 | -0.151372 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.117352 |
| VIM | vimentin | -0.110654 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.106985 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102113 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0978141 |
| TMSB10 | thymosin beta 10 | -0.0961084 |
| TENM3 | teneurin transmembrane protein 3 | -0.0844393 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0835022 |
| CADM2 | cell adhesion molecule 2 | -0.0827771 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0795166 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0714643 |
| RPS16 | ribosomal protein S16 | -0.0702683 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0694281 |
| RPS12 | ribosomal protein S12 | -0.0690456 |
| PTMA | prothymosin, alpha | -0.0660191 |
| RPL23 | ribosomal protein L23 | -0.0612861 |
| RPLP1 | ribosomal protein, large, P1 | -0.0590292 |
| ACTG1 | actin gamma 1 | -0.0584661 |
| GNAS | GNAS complex locus | -0.0568706 |
| RPS8 | ribosomal protein S8 | -0.0568666 |
| PHIP | pleckstrin homology domain interacting protein | -0.0557393 |
| COL5A2 | collagen, type V, alpha 2 | -0.0551638 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0541442 |
| LRRC4C | leucine rich repeat containing 4C | -0.0539419 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0527778 |
| RPS6 | ribosomal protein S6 | -0.0519255 |
| GPC3 | glypican 3 | -0.0518901 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0503562 |
| PGK1 | phosphoglycerate kinase 1 | -0.0490296 |
| RPS19 | ribosomal protein S19 | -0.0481882 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0463325 |
| NPAS3 | neuronal PAS domain protein 3 | -0.046181 |
| RPLP0 | ribosomal protein, large, P0 | -0.0459754 |
| YBX1 | Y box binding protein 1 | -0.0453039 |
| PCDH9 | protocadherin 9 | -0.0446667 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0437468 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0434735 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0431806 |
| RAD51B | RAD51 paralog B | -0.0430389 |
| USP34 | ubiquitin specific peptidase 34 | -0.0415114 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0414407 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0409787 |
| NTM | neurotrimin | -0.0405968 |
| RPL19 | ribosomal protein L19 | -0.0403202 |
| RPS21 | ribosomal protein S21 | -0.0401061 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0400776 |
| CALR | calreticulin | -0.0399405 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0398815 |
| CENPF | centromere protein F, 350/400kDa | -0.0390924 |
| ENO1 | enolase 1, (alpha) | -0.0387018 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0385136 |
| LDHA | lactate dehydrogenase A | -0.0383125 |
| RPL35A | ribosomal protein L35a | -0.0379544 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0374206 |
| RPL11 | ribosomal protein L11 | -0.0369579 |
| NEBL | nebulette | -0.0368859 |
| CDH19 | cadherin 19, type 2 | -0.0359688 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0359222 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0357083 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0350153 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0338051 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0336204 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0334828 |
| FBXO11 | F-box protein 11 | -0.0333271 |
| RPL26 | ribosomal protein L26 | -0.0331877 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0324996 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0323337 |
| UBC | ubiquitin C | -0.032225 |
| RPL37A | ribosomal protein L37a | -0.0316613 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0307925 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0306225 |
| RPL34 | ribosomal protein L34 | -0.0305158 |
| RPL12 | ribosomal protein L12 | -0.0301393 |
| NHSL1 | NHS-like 1 | -0.0297199 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0297086 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0295991 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0294462 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0293572 |
| RPLP2 | ribosomal protein, large, P2 | -0.0289302 |
| B2M | beta-2-microglobulin | -0.0286817 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0281898 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0279182 |
| BPTF | bromodomain PHD finger transcription factor | -0.0277552 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0275075 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0272373 |
| FST | follistatin | -0.0269669 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.026462 |
| RPS27A | ribosomal protein S27a | -0.0260783 |
| RPL30 | ribosomal protein L30 | -0.0260548 |
| CDK6 | cyclin-dependent kinase 6 | -0.0259829 |
| URI1 | URI1, prefoldin-like chaperone | -0.0257704 |
| PRELID2 | PRELI domain containing 2 | -0.0256787 |
| S100A10 | S100 calcium binding protein A10 | -0.0254665 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0251005 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0248935 |
| PKM | pyruvate kinase, muscle | -0.0247574 |
| PRR16 | proline rich 16 | -0.0247299 |
| HSPB1 | heat shock 27kDa protein 1 | -0.024671 |
