| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.174557 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.140876 |
| VIM | vimentin | 0.108677 |
| FN1 | fibronectin 1 | 0.108119 |
| B2M | beta-2-microglobulin | 0.103291 |
| STC1 | stanniocalcin 1 | 0.0782925 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0758602 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0756926 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0737163 |
| CD44 | CD44 molecule (Indian blood group) | 0.0721835 |
| CENPF | centromere protein F, 350/400kDa | 0.070675 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0685607 |
| PGK1 | phosphoglycerate kinase 1 | 0.0677814 |
| GOLGA4 | golgin A4 | 0.0644724 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0607404 |
| COL1A2 | collagen, type I, alpha 2 | 0.0587941 |
| RAB7A | RAB7A, member RAS oncogene family | 0.057316 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0565441 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0559414 |
| COL1A1 | collagen, type I, alpha 1 | 0.0554849 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0545451 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0544588 |
| ATP13A3 | ATPase type 13A3 | 0.0543273 |
| ANLN | anillin, actin binding protein | 0.0541008 |
| THBS1 | thrombospondin 1 | 0.05232 |
| HLA-B | major histocompatibility complex, class I, B | 0.0516297 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0515102 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0510513 |
| MKI67 | marker of proliferation Ki-67 | 0.0508632 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0505262 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0499254 |
| ENO1 | enolase 1, (alpha) | 0.0488859 |
| ZNF292 | zinc finger protein 292 | 0.0486352 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0455167 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0452746 |
| RBM39 | RNA binding motif protein 39 | 0.0450828 |
| JMJD1C | jumonji domain containing 1C | 0.0449075 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0442942 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0442598 |
| CALU | calumenin | 0.0442123 |
| CCNL1 | cyclin L1 | 0.0436666 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0435281 |
| ECT2 | epithelial cell transforming 2 | 0.0409076 |
| NF1 | neurofibromin 1 | 0.0404329 |
| NUP58 | nucleoporin 58 | 0.0400699 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0398017 |
| FNIP1 | folliculin interacting protein 1 | 0.0395785 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0395677 |
| NCKAP1 | NCK-associated protein 1 | 0.039465 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0389962 |
| PTK2 | protein tyrosine kinase 2 | 0.0386668 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.037919 |
| DIAPH3 | diaphanous-related formin 3 | 0.037862 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0378473 |
| SETD2 | SET domain containing 2 | 0.0373566 |
| XPO1 | exportin 1 | 0.0373232 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0372329 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0371956 |
| INHBA | inhibin, beta A | 0.0371811 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0371292 |
| CENPE | centromere protein E, 312kDa | 0.0366357 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0362288 |
| RLF | rearranged L-myc fusion | 0.0362182 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0361139 |
| QKI | QKI, KH domain containing, RNA binding | 0.0359739 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0359561 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.035776 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0355055 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0349596 |
| TPX2 | TPX2, microtubule-associated | 0.0348983 |
| SPAG9 | sperm associated antigen 9 | 0.0348621 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0346537 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.034084 |
| H1-0 | H1.0 linker histone | 0.0340129 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0335193 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0335192 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0334495 |
| KIF5B | kinesin family member 5B | 0.0333094 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0328704 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0328561 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0327287 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | 0.0327199 |
| SMAD3 | SMAD family member 3 | 0.031996 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0319954 |
| SLMAP | sarcolemma associated protein | 0.0316973 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0315518 |
| MED13L | mediator complex subunit 13-like | 0.0315146 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0312878 |
| MSR1 | macrophage scavenger receptor 1 | 0.0310672 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0309954 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0307652 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.030757 |
| SON | SON DNA binding protein | 0.0306922 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0298828 |
| PTMA | prothymosin, alpha | 0.0298485 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0298318 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0297936 |
| CRY1 | cryptochrome circadian clock 1 | 0.0297648 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0295975 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0293146 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0725755 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0577829 |
| NDRG1 | N-myc downstream regulated 1 | -0.0519041 |
| CDH13 | cadherin 13 | -0.0472832 |
| FHIT | fragile histidine triad | -0.0428687 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0386195 |
| RAD51B | RAD51 paralog B | -0.0372367 |
| ASPH | aspartate beta-hydroxylase | -0.0360941 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0354129 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0309604 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0300492 |
| LOXL2 | lysyl oxidase-like 2 | -0.0297389 |
| INTS6 | integrator complex subunit 6 | -0.0286489 |
| PCBP3 | poly(rC) binding protein 3 | -0.0284565 |
| EGFR | epidermal growth factor receptor | -0.0282746 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0277889 |
| COL5A1 | collagen, type V, alpha 1 | -0.0275751 |
| FBXO32 | F-box protein 32 | -0.0265118 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0256885 |
| CADM1 | cell adhesion molecule 1 | -0.0252548 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0246488 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0232556 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.023061 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0224264 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0221592 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0213656 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0212766 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0202298 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0198893 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0198545 |
| SHISA5 | shisa family member 5 | -0.0198498 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.019774 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0192862 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0192861 |
| TMEM178B | transmembrane protein 178B | -0.0192681 |
| EXOC4 | exocyst complex component 4 | -0.0187819 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0187004 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0186214 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0185558 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0182874 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0182026 |
| HDAC9 | histone deacetylase 9 | -0.018128 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0178054 |
| NABP1 | nucleic acid binding protein 1 | -0.0171182 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0171118 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0168847 |
| VCL | vinculin | -0.0168084 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0166584 |
| VEGFA | vascular endothelial growth factor A | -0.0165911 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.016524 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0164874 |
| FAM20C | family with sequence similarity 20, member C | -0.0162701 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0162378 |
| NAV1 | neuron navigator 1 | -0.0161624 |
| SP100 | SP100 nuclear antigen | -0.0160834 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0159459 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0159163 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0158808 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0157753 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0152237 |
| FTL | ferritin, light polypeptide | -0.0152226 |
| TENM4 | teneurin transmembrane protein 4 | -0.0151648 |
| LRRC23 | leucine rich repeat containing 23 | -0.0149911 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0148083 |
| TGFB1 | transforming growth factor, beta 1 | -0.0146518 |
| MMP12 | matrix metallopeptidase 12 | -0.0145948 |
| SYNDIG1 | synapse differentiation inducing 1 | -0.0145906 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0144254 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0144161 |
| HDAC4 | histone deacetylase 4 | -0.0141837 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0140527 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0140485 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0140478 |
| MYO1E | myosin IE | -0.0138833 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0138787 |
| OXR1 | oxidation resistance 1 | -0.013737 |
| SMYD3 | SET and MYND domain containing 3 | -0.0135408 |
| WWOX | WW domain containing oxidoreductase | -0.0135196 |
| TNS3 | tensin 3 | -0.0134733 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.013468 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0133735 |
| RNF213 | ring finger protein 213 | -0.0133649 |
| HYOU1 | hypoxia up-regulated 1 | -0.0128797 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0128264 |
| DGKI | diacylglycerol kinase, iota | -0.012821 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0128038 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0127321 |
| TMEM263 | transmembrane protein 263 | -0.012712 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0126733 |
| CCDC138 | coiled-coil domain containing 138 | -0.012672 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -0.0125422 |
| NPAS2 | neuronal PAS domain protein 2 | -0.012406 |
| MTSS1 | metastasis suppressor 1 | -0.0121474 |
| AGBL1 | ATP/GTP binding protein-like 1 | -0.0121429 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0121143 |
| MYO9A | myosin IXA | -0.0121033 |
| CFAP20DC | CFAP20 domain containing | -0.0119009 |
| AEBP2 | AE binding protein 2 | -0.0118857 |
| PLSCR2 | phospholipid scramblase 2 | -0.0118626 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0117488 |
