| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ouabain (Octahydrate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TENM1 | teneurin transmembrane protein 1 | 0.174764 |
| PDE10A | phosphodiesterase 10A | 0.118742 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0885551 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.059434 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0572409 |
| CENPF | centromere protein F, 350/400kDa | 0.0507938 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0454125 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0421907 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0416886 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0399549 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0363226 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0340089 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0322971 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0314751 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0314204 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0295417 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0283432 |
| ECT2 | epithelial cell transforming 2 | 0.0274219 |
| FAT1 | FAT atypical cadherin 1 | 0.0269915 |
| XPO1 | exportin 1 | 0.0263624 |
| FLOT1 | flotillin 1 | 0.026129 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0259642 |
| PCM1 | pericentriolar material 1 | 0.0237315 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0232109 |
| UBC | ubiquitin C | 0.0230533 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0225126 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0224172 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0222552 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0220946 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0217796 |
| AURKA | aurora kinase A | 0.0217211 |
| CCNB1 | cyclin B1 | 0.0216754 |
| ENO1 | enolase 1, (alpha) | 0.0214533 |
| IRS2 | insulin receptor substrate 2 | 0.0214532 |
| TPX2 | TPX2, microtubule-associated | 0.0214445 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0208569 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0204982 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0204952 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0204069 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0201848 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0201645 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0200353 |
| AHR | aryl hydrocarbon receptor | 0.0199865 |
| GRAMD1B | GRAM domain containing 1B | 0.0198387 |
| MT2A | metallothionein 2A | 0.0196264 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.01943 |
| ANLN | anillin, actin binding protein | 0.0190485 |
| CDCA2 | cell division cycle associated 2 | 0.019015 |
| TTK | TTK protein kinase | 0.018833 |
| APP | amyloid beta (A4) precursor protein | 0.0186356 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0185138 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.018428 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.018386 |
| KIF5B | kinesin family member 5B | 0.018376 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0182873 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0182645 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0175583 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0171573 |
| PEG10 | paternally expressed 10 | 0.0170737 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.017064 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0169305 |
| KNL1 | kinetochore scaffold 1 | 0.0169141 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0168459 |
| GOLIM4 | golgi integral membrane protein 4 | 0.016667 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | 0.0166455 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0164305 |
| MYEF2 | myelin expression factor 2 | 0.016397 |
| DUSP4 | dual specificity phosphatase 4 | 0.0163906 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0163372 |
| KIAA0586 | KIAA0586 | 0.0160785 |
| PCBP2 | poly(rC) binding protein 2 | 0.0159739 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0157397 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0155434 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0154777 |
| CENPE | centromere protein E, 312kDa | 0.0154751 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0149776 |
| SGO2 | shugoshin 2 | 0.0147678 |
| SPAG5 | sperm associated antigen 5 | 0.0147646 |
| ATF3 | activating transcription factor 3 | 0.0147356 |
| NPTN | neuroplastin | 0.0145959 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0145004 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0143201 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0141118 |
| MTMR7 | myotubularin related protein 7 | 0.0140847 |
| KIF11 | kinesin family member 11 | 0.014032 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.0139654 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0139335 |
| GPRIN3 | GPRIN family member 3 | 0.0139329 |
| GPSM2 | G-protein signaling modulator 2 | 0.0138417 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0138039 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0137387 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0137016 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0135891 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0135883 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0134673 |
| CEP70 | centrosomal protein 70kDa | 0.01338 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0133051 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0133045 |
| STK24 | serine/threonine kinase 24 | 0.0133041 |
| NCKAP1 | NCK-associated protein 1 | 0.0132944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.180789 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.128105 |
| GPC6 | glypican 6 | -0.106245 |
| NRG1 | neuregulin 1 | -0.0976412 |
| SCG2 | secretogranin II | -0.0917303 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0879845 |
| STC1 | stanniocalcin 1 | -0.0856568 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.08085 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0795013 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0723908 |
| SNTG1 | syntrophin, gamma 1 | -0.0719498 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0644084 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0624689 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0605974 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0587731 |
| ACTG1 | actin gamma 1 | -0.0555278 |
| NDRG1 | N-myc downstream regulated 1 | -0.0553279 |
| RPL37A | ribosomal protein L37a | -0.0510447 |
| CHGB | chromogranin B | -0.0480613 |
| SMYD3 | SET and MYND domain containing 3 | -0.0478421 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0475327 |
| RORA | RAR-related orphan receptor A | -0.0475035 |
| DTNA | dystrobrevin, alpha | -0.0473324 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0466738 |
| LSAMP | limbic system-associated membrane protein | -0.0465634 |
| RGS7 | regulator of G-protein signaling 7 | -0.0460389 |
| MAP1B | microtubule-associated protein 1B | -0.0459712 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0441698 |
| TMSB4X | thymosin beta 4, X-linked | -0.0440657 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0439284 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0434871 |
| RPS6 | ribosomal protein S6 | -0.0427301 |
| EGR1 | early growth response 1 | -0.0425584 |
| STXBP5L | syntaxin binding protein 5-like | -0.0423965 |
| KIF26B | kinesin family member 26B | -0.0418132 |
| S100A9 | S100 calcium binding protein A9 | -0.0417501 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0404028 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0403255 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0400472 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0400458 |
| ESRRG | estrogen-related receptor gamma | -0.0396402 |
| SQSTM1 | sequestosome 1 | -0.0386138 |
| RPL38 | ribosomal protein L38 | -0.0382555 |
| PTMA | prothymosin, alpha | -0.0380323 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0378895 |
| HM13 | histocompatibility (minor) 13 | -0.0372933 |
| KLHL29 | kelch-like family member 29 | -0.0371736 |
| TXNIP | thioredoxin interacting protein | -0.0362882 |
| RPS21 | ribosomal protein S21 | -0.0362628 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0357612 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | -0.0355605 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0347582 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.03463 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0344474 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0342125 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0341588 |
| EPHA6 | EPH receptor A6 | -0.0326846 |
| FTL | ferritin, light polypeptide | -0.0325793 |
| RPL37 | ribosomal protein L37 | -0.0325309 |
| DENND4A | DENN/MADD domain containing 4A | -0.0321696 |
| GPC5 | glypican 5 | -0.0320825 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0318637 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0316347 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0312287 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -0.031104 |
| NBEA | neurobeachin | -0.0310515 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0309853 |
| RPL26 | ribosomal protein L26 | -0.0307474 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0307119 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.030233 |
| RPLP1 | ribosomal protein, large, P1 | -0.0299924 |
| SETX | senataxin | -0.0297158 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0292164 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.02911 |
| RPS16 | ribosomal protein S16 | -0.0288075 |
| B2M | beta-2-microglobulin | -0.0285814 |
| CNKSR3 | CNKSR family member 3 | -0.0282239 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0280303 |
| RPS19 | ribosomal protein S19 | -0.0279098 |
| ARFGEF3 | ARFGEF family member 3 | -0.0276235 |
| RPS25 | ribosomal protein S25 | -0.0273823 |
| GNAS | GNAS complex locus | -0.0270119 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0269684 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0268629 |
| ZFHX3 | zinc finger homeobox 3 | -0.0267428 |
| GOLGB1 | golgin B1 | -0.0265834 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -0.0264527 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0261591 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0256883 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0256741 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0253947 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0253335 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0249032 |
| HOMER1 | homer scaffolding protein 1 | -0.0248822 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0248455 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0247447 |
| SEC11C | SEC11 homolog C (S. cerevisiae) | -0.0247175 |
| TUSC3 | tumor suppressor candidate 3 | -0.0240544 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0240173 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0237955 |
