| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.207111 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.109669 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0946661 |
| ATP13A3 | ATPase type 13A3 | 0.0676372 |
| IL6 | interleukin 6 | 0.0594412 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0592013 |
| VEGFA | vascular endothelial growth factor A | 0.0588023 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0561128 |
| KYNU | kynureninase | 0.0521599 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0479632 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0471774 |
| CADM1 | cell adhesion molecule 1 | 0.0468747 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0465961 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0463857 |
| RUNX1 | runt-related transcription factor 1 | 0.0436791 |
| RNF145 | ring finger protein 145 | 0.0433611 |
| EGFR | epidermal growth factor receptor | 0.0430159 |
| FNDC3B | fibronectin type III domain containing 3B | 0.04267 |
| PTK2 | protein tyrosine kinase 2 | 0.039394 |
| SNX13 | sorting nexin 13 | 0.0375202 |
| ANXA5 | annexin A5 | 0.0371842 |
| TNS3 | tensin 3 | 0.037099 |
| CALD1 | caldesmon 1 | 0.036737 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0355599 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0354628 |
| NUP58 | nucleoporin 58 | 0.035128 |
| PRRC2C | proline-rich coiled-coil 2C | 0.035125 |
| VEGFC | vascular endothelial growth factor C | 0.0344658 |
| B2M | beta-2-microglobulin | 0.0339873 |
| SRPK2 | SRSF protein kinase 2 | 0.0335822 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0335132 |
| MSN | moesin | 0.0329127 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0328267 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0321011 |
| ARRDC3 | arrestin domain containing 3 | 0.0319984 |
| PARD3 | par-3 family cell polarity regulator | 0.030963 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0309468 |
| PRKCA | protein kinase C, alpha | 0.0308565 |
| CDH13 | cadherin 13 | 0.0304179 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0303657 |
| NRXN3 | neurexin 3 | 0.0298238 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.029418 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0293956 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0288848 |
| CUL3 | cullin 3 | 0.0286473 |
| COL5A1 | collagen, type V, alpha 1 | 0.0285706 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0285211 |
| HDAC9 | histone deacetylase 9 | 0.0284055 |
| TOP1 | topoisomerase (DNA) I | 0.0284034 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.027289 |
| JMJD1C | jumonji domain containing 1C | 0.0270974 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0270512 |
| RND3 | Rho family GTPase 3 | 0.0267973 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0265387 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0264143 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0263694 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0260832 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0259747 |
| CCNL1 | cyclin L1 | 0.0258437 |
| LAMB1 | laminin, beta 1 | 0.0256386 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0255484 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0254862 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0252172 |
| AHR | aryl hydrocarbon receptor | 0.0251249 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0250548 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0248819 |
| SMAD3 | SMAD family member 3 | 0.0247379 |
| CALR | calreticulin | 0.0246886 |
| ERBIN | erbb2 interacting protein | 0.0246654 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0244496 |
| NAV2 | neuron navigator 2 | 0.0239018 |
| SEC24B | SEC24 family member B | 0.0238572 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0236451 |
| PGK1 | phosphoglycerate kinase 1 | 0.0235843 |
| CARD16 | caspase recruitment domain family, member 16 | 0.023442 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0231571 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0229318 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0228546 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0226235 |
| FRMD4A | FERM domain containing 4A | 0.0224518 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0221875 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.022179 |
| INSIG1 | insulin induced gene 1 | 0.0221004 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0220617 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0219845 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0217429 |
| MRTFA | myocardin related transcription factor A | 0.0217373 |
| MAP4 | microtubule-associated protein 4 | 0.0217264 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0216955 |
| THOC2 | THO complex 2 | 0.0216506 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0215737 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.021389 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0212267 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0211672 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0211245 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0211234 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0210694 |
| STK17A | serine/threonine kinase 17a | 0.0210449 |
| FNIP1 | folliculin interacting protein 1 | 0.0207614 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0206289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157568 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.148717 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0626976 |
| LOXL2 | lysyl oxidase-like 2 | -0.0623298 |
| HLA-C | major histocompatibility complex, class I, C | -0.0488757 |
| CANX | calnexin | -0.046971 |
| PTMA | prothymosin, alpha | -0.0453054 |
| OGA | O-GlcNAcase | -0.0443825 |
| TMSB10 | thymosin beta 10 | -0.0433376 |
| MAP1B | microtubule-associated protein 1B | -0.0421536 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0411758 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0408122 |
| ANXA2 | annexin A2 | -0.0405888 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0404458 |
| PRSS23 | protease, serine, 23 | -0.0404174 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0402153 |
| COL1A2 | collagen, type I, alpha 2 | -0.0397526 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0395869 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0395361 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0367787 |
| CCNI | cyclin I | -0.0362827 |
| SRP54 | signal recognition particle 54kDa | -0.0361043 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0356807 |
| ARF1 | ADP-ribosylation factor 1 | -0.0355541 |
| COG5 | component of oligomeric golgi complex 5 | -0.035278 |
| HDLBP | high density lipoprotein binding protein | -0.034493 |
| MYOF | myoferlin | -0.033952 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0334772 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0327276 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0325355 |
| ANO6 | anoctamin 6 | -0.0315938 |
| HM13 | histocompatibility (minor) 13 | -0.0308494 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0305809 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0299852 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0293548 |
| CAVIN1 | caveolae associated protein 1 | -0.0293503 |
| SDC4 | syndecan 4 | -0.0285814 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0275368 |
| MEF2A | myocyte enhancer factor 2A | -0.0272585 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0265509 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0256424 |
| GNAS | GNAS complex locus | -0.0256327 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0254887 |
| TFG | TRK-fused gene | -0.0251881 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0250041 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0248223 |
| FUS | FUS RNA binding protein | -0.0246791 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0243319 |
| HMGB1 | high mobility group box 1 | -0.0241787 |
| USP37 | ubiquitin specific peptidase 37 | -0.0241247 |
| HLA-A | major histocompatibility complex, class I, A | -0.024083 |
| PTGES2 | prostaglandin E synthase 2 | -0.023466 |
| STC1 | stanniocalcin 1 | -0.0234339 |
| TUBB | tubulin, beta class I | -0.0231123 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0230778 |
| SEPTIN2 | septin 2 | -0.0230474 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0225368 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0223927 |
| THY1 | Thy-1 cell surface antigen | -0.0220761 |
| WASF2 | WAS protein family, member 2 | -0.0219644 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0218492 |
| PCM1 | pericentriolar material 1 | -0.0214356 |
| CLIC4 | chloride intracellular channel 4 | -0.0213808 |
| RPN2 | ribophorin II | -0.0211846 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0211652 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0211174 |
| SSR1 | signal sequence receptor, alpha | -0.0210463 |
| HMGB2 | high mobility group box 2 | -0.020958 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0207367 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0204487 |
| KLHDC10 | kelch domain containing 10 | -0.0203513 |
| SRGN | serglycin | -0.020132 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0200684 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0199514 |
| RAB10 | RAB10, member RAS oncogene family | -0.0199311 |
| RPL28 | ribosomal protein L28 | -0.0197193 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0196328 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0196174 |
| TPX2 | TPX2, microtubule-associated | -0.0195483 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0193916 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.019302 |
| PDE10A | phosphodiesterase 10A | -0.0191982 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0191868 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0191474 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0190657 |
| UBC | ubiquitin C | -0.0190154 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0189112 |
| PMM2 | phosphomannomutase 2 | -0.0189071 |
| ANGPTL4 | angiopoietin-like 4 | -0.0188621 |
| SUCO | SUN domain containing ossification factor | -0.0186634 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0186212 |
| CD99 | CD99 molecule | -0.0185313 |
| NABP1 | nucleic acid binding protein 1 | -0.0182271 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0180371 |
| NAV1 | neuron navigator 1 | -0.0179503 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0178184 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0176666 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0175518 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0175268 |
| TUBA1B | tubulin, alpha 1b | -0.0175066 |
