| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.119844 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0949549 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0791628 |
| SPAG9 | sperm associated antigen 9 | 0.0761458 |
| PTMA | prothymosin, alpha | 0.0737069 |
| NUP58 | nucleoporin 58 | 0.0655894 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0585804 |
| RBM39 | RNA binding motif protein 39 | 0.0549827 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0543372 |
| CRY1 | cryptochrome circadian clock 1 | 0.0531765 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0514299 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0510832 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0485093 |
| DIAPH1 | diaphanous-related formin 1 | 0.0482956 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0460563 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0444688 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0439822 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0431218 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0412349 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0407833 |
| PKM | pyruvate kinase, muscle | 0.0403886 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0396823 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.038799 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0387919 |
| ANLN | anillin, actin binding protein | 0.0383795 |
| ANXA1 | annexin A1 | 0.0370947 |
| QKI | QKI, KH domain containing, RNA binding | 0.0367532 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0364899 |
| UBC | ubiquitin C | 0.0342197 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0339469 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0335211 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0332717 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0331835 |
| TXNRD1 | thioredoxin reductase 1 | 0.0326838 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0326581 |
| ECT2 | epithelial cell transforming 2 | 0.0324228 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0321222 |
| SET | SET nuclear proto-oncogene | 0.0300361 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0298004 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0295692 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0294543 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0293472 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0287382 |
| OXSR1 | oxidative stress responsive 1 | 0.0283801 |
| YBX3 | Y box binding protein 3 | 0.0276865 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0273056 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0269134 |
| AHR | aryl hydrocarbon receptor | 0.025671 |
| RNF145 | ring finger protein 145 | 0.0255327 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0252782 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0252607 |
| MATR3 | matrin 3 | 0.025157 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0251385 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0251204 |
| GOLGA4 | golgin A4 | 0.0248161 |
| NKTR | natural killer cell triggering receptor | 0.0244511 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0242243 |
| ADM | adrenomedullin | 0.0239492 |
| RHEB | Ras homolog enriched in brain | 0.0239376 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.023826 |
| JMJD1C | jumonji domain containing 1C | 0.0237943 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0237885 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0237172 |
| INSIG1 | insulin induced gene 1 | 0.0234492 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0234186 |
| NUP153 | nucleoporin 153kDa | 0.0233333 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0232065 |
| TFG | TRK-fused gene | 0.0231794 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0231446 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0230975 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0230346 |
| MORF4L1 | mortality factor 4 like 1 | 0.0228146 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0224819 |
| BRD2 | bromodomain containing 2 | 0.0224289 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0221376 |
| TPX2 | TPX2, microtubule-associated | 0.022014 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0219206 |
| SEC24A | SEC24 family member A | 0.0217517 |
| POTEF | POTE ankyrin domain family, member F | 0.0216599 |
| RLF | rearranged L-myc fusion | 0.0216285 |
| PER1 | period circadian clock 1 | 0.0212954 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0209562 |
| SEPTIN7 | septin 7 | 0.0208801 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0207787 |
| PDS5B | PDS5 cohesin associated factor B | 0.0206577 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0206056 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0204004 |
| CCNL1 | cyclin L1 | 0.0203922 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0203374 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0202311 |
| TOP1 | topoisomerase (DNA) I | 0.0202228 |
| WDR43 | WD repeat domain 43 | 0.0199996 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0199098 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0195251 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0195101 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0195064 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0194417 |
| LDHA | lactate dehydrogenase A | 0.0193641 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0192381 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0189031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMYD3 | SET and MYND domain containing 3 | -0.0673849 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0504998 |
| RAD51B | RAD51 paralog B | -0.0398273 |
| ATM | ATM serine/threonine kinase | -0.0390162 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.037277 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0368571 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0335257 |
| DNER | delta/notch-like EGF repeat containing | -0.0319291 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0296103 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0286693 |
| OSMR | oncostatin M receptor | -0.0284888 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0279052 |
| ATXN1 | ataxin 1 | -0.0258164 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0253688 |
| FMN1 | formin 1 | -0.0246445 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0242222 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0240115 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0239078 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0238421 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0234694 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0228519 |
| PHF3 | PHD finger protein 3 | -0.0227346 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0226029 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0225865 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0224679 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0223606 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0216513 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.02121 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0211566 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0210192 |
| GPC6 | glypican 6 | -0.0209966 |
| EXOC4 | exocyst complex component 4 | -0.0208564 |
| PRELID2 | PRELI domain containing 2 | -0.0204842 |
| VCL | vinculin | -0.0201313 |
| CEP290 | centrosomal protein 290kDa | -0.0201122 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0200845 |
| FLNB | filamin B, beta | -0.0199025 |
| RANBP17 | RAN binding protein 17 | -0.0198983 |
| RORA | RAR-related orphan receptor A | -0.0197512 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0195888 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0192022 |
| PHF21A | PHD finger protein 21A | -0.019156 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0191284 |
| EFNA5 | ephrin-A5 | -0.0189729 |
| MYO9A | myosin IXA | -0.0188044 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0186967 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0184312 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0184272 |
| AHNAK | AHNAK nucleoprotein | -0.0182761 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.018232 |
| TMEM14B | transmembrane protein 14B | -0.0180416 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.017533 |
| NAV2 | neuron navigator 2 | -0.0175212 |
| PHF14 | PHD finger protein 14 | -0.017513 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0174694 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.01731 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0171519 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0170993 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0170699 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0170322 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0168168 |
| UTRN | utrophin | -0.0164097 |
| CCDC91 | coiled-coil domain containing 91 | -0.0162058 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0159914 |
| BBX | bobby sox homolog (Drosophila) | -0.0159749 |
| ACER3 | alkaline ceramidase 3 | -0.0158413 |
| NBEA | neurobeachin | -0.0157148 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0156911 |
| FMNL2 | formin-like 2 | -0.0155744 |
| WWOX | WW domain containing oxidoreductase | -0.0153235 |
| NALCN | sodium leak channel, non selective | -0.0152863 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0152659 |
| RAD50 | RAD50 homolog (S. cerevisiae) | -0.0152263 |
| CDCP1 | CUB domain containing protein 1 | -0.0150957 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0148724 |
| LRRC49 | leucine rich repeat containing 49 | -0.0145624 |
| EXOC6B | exocyst complex component 6B | -0.0145575 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0144556 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0143493 |
| HLA-C | major histocompatibility complex, class I, C | -0.0143361 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0143253 |
| WDR70 | WD repeat domain 70 | -0.0142745 |
| GPHN | gephyrin | -0.0141872 |
| ETV6 | ets variant 6 | -0.014181 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0141715 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.014095 |
| SRBD1 | S1 RNA binding domain 1 | -0.0140896 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0140739 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0138275 |
| ASPH | aspartate beta-hydroxylase | -0.0137712 |
| ATG10 | autophagy related 10 | -0.0137643 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0137074 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | -0.0135299 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0134185 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0133088 |
| HDAC9 | histone deacetylase 9 | -0.0132015 |
| KIAA1328 | KIAA1328 | -0.0131718 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0131024 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0130149 |
| EGR1 | early growth response 1 | -0.0130104 |
