| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.147333 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0818169 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.055823 |
| MT2A | metallothionein 2A | 0.0549167 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0497353 |
| FAT1 | FAT atypical cadherin 1 | 0.0490783 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0486629 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0454226 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0445311 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.042898 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0424738 |
| INSIG1 | insulin induced gene 1 | 0.0383149 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0370619 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0307845 |
| SMAD3 | SMAD family member 3 | 0.0282979 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.027889 |
| CDCP1 | CUB domain containing protein 1 | 0.0271522 |
| OSMR | oncostatin M receptor | 0.027031 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0257407 |
| IL6ST | interleukin 6 signal transducer | 0.0249898 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0246039 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0245518 |
| WDR26 | WD repeat domain 26 | 0.0234832 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0230784 |
| ZFP36 | ZFP36 ring finger protein | 0.0223114 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0221135 |
| CAB39 | calcium binding protein 39 | 0.0220258 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.021917 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.021103 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0203749 |
| MCL1 | myeloid cell leukemia 1 | 0.020028 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0200041 |
| FAF2 | Fas associated factor family member 2 | 0.0199948 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0183838 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.018118 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0172918 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0172345 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0169616 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0167847 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0167647 |
| RUNX1 | runt-related transcription factor 1 | 0.0167348 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0167332 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0165201 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0164123 |
| SMOX | spermine oxidase | 0.0163309 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0162048 |
| PER1 | period circadian clock 1 | 0.0157888 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0157034 |
| MTMR3 | myotubularin related protein 3 | 0.0156728 |
| USP53 | ubiquitin specific peptidase 53 | 0.0156418 |
| RAB28 | RAB28, member RAS oncogene family | 0.0155952 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0155883 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.015566 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.0153404 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0152312 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0150821 |
| MKI67 | marker of proliferation Ki-67 | 0.0149215 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0149124 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0149121 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0148471 |
| SRPK1 | SRSF protein kinase 1 | 0.0145077 |
| STK38L | serine/threonine kinase 38 like | 0.0145072 |
| FLNA | filamin A, alpha | 0.0144958 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0144577 |
| FOXP1 | forkhead box P1 | 0.0144362 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0140791 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0140717 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0140472 |
| HDAC9 | histone deacetylase 9 | 0.0139353 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta | 0.0138842 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0138753 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0138647 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0138337 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0138224 |
| ARRDC3 | arrestin domain containing 3 | 0.0137778 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0136249 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0134203 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0133386 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0133292 |
| ITGB5 | integrin, beta 5 | 0.013215 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0131025 |
| ANGPTL4 | angiopoietin-like 4 | 0.0130563 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0130144 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0129829 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0128576 |
| ATXN1 | ataxin 1 | 0.0128187 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0125902 |
| ITGAV | integrin, alpha V | 0.0125336 |
| DBF4 | DBF4 zinc finger | 0.0124498 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.012437 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0123965 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0123956 |
| KIAA1217 | KIAA1217 | 0.0123473 |
| PCNX1 | pecanex 1 | 0.0123445 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.012324 |
| FRYL | FRY-like | 0.0122915 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0121632 |
| CCNL1 | cyclin L1 | 0.0121084 |
| DNMBP | dynamin binding protein | 0.0120393 |
| OGA | O-GlcNAcase | 0.0120001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.212214 |
| FN1 | fibronectin 1 | -0.122113 |
| PTMA | prothymosin, alpha | -0.109867 |
| SQSTM1 | sequestosome 1 | -0.0943166 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0892208 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0852808 |
| NRG1 | neuregulin 1 | -0.0814511 |
| FTL | ferritin, light polypeptide | -0.0796 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0738905 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0729682 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0695602 |
| CANX | calnexin | -0.0642382 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0639363 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0617751 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0594422 |
| LMNA | lamin A/C | -0.0577334 |
| RAI14 | retinoic acid induced 14 | -0.0537161 |
| TMSB4X | thymosin beta 4, X-linked | -0.0532524 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0513324 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0506367 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0501299 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0480261 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0479687 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0426044 |
| GLIS3 | GLIS family zinc finger 3 | -0.0409094 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0397355 |
| S100A10 | S100 calcium binding protein A10 | -0.0386425 |
| RAB1A | RAB1A, member RAS oncogene family | -0.038127 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0379542 |
| ZNF292 | zinc finger protein 292 | -0.0376615 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0367671 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0365259 |
| COPA | coatomer protein complex, subunit alpha | -0.0364842 |
| TMSB10 | thymosin beta 10 | -0.036226 |
| NOP58 | NOP58 ribonucleoprotein | -0.0359075 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.035716 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0356824 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0356469 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0353765 |
| SYT1 | synaptotagmin I | -0.0352904 |
| CALR | calreticulin | -0.0348611 |
| SUCO | SUN domain containing ossification factor | -0.0335392 |
| DSTN | destrin (actin depolymerizing factor) | -0.0331099 |
| ARF1 | ADP-ribosylation factor 1 | -0.032964 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0326756 |
| SPAG9 | sperm associated antigen 9 | -0.0325375 |
| S100A6 | S100 calcium binding protein A6 | -0.0321494 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0317118 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0315797 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0315772 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0315415 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0315363 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0315029 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0307646 |
| AOPEP | aminopeptidase O (putative) | -0.0307607 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0304539 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0303454 |
| HMGA2 | high mobility group AT-hook 2 | -0.0298273 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.029749 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0295313 |
| GNAS | GNAS complex locus | -0.0294606 |
| STC2 | stanniocalcin 2 | -0.0292289 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0290207 |
| YBX3 | Y box binding protein 3 | -0.0286598 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0285896 |
| QKI | QKI, KH domain containing, RNA binding | -0.0280162 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0280039 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0277961 |
| CTBP2 | C-terminal binding protein 2 | -0.0275947 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0275153 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0274396 |
| CADM1 | cell adhesion molecule 1 | -0.0273195 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0271298 |
| COG5 | component of oligomeric golgi complex 5 | -0.0264847 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0260755 |
| RACK1 | receptor for activated C kinase 1 | -0.0260568 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0259394 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0254988 |
| GLG1 | golgi glycoprotein 1 | -0.025437 |
| TXNIP | thioredoxin interacting protein | -0.0253175 |
| NCOA7 | nuclear receptor coactivator 7 | -0.024985 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0249758 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0249067 |
| SEC24A | SEC24 family member A | -0.0248526 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0248464 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0248359 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.02481 |
| H1-0 | H1.0 linker histone | -0.0248082 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0248038 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0246231 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0244727 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0244709 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0243757 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0243039 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0240771 |
| KLHL24 | kelch-like family member 24 | -0.024044 |
| HLA-B | major histocompatibility complex, class I, B | -0.0239968 |
| TFG | TRK-fused gene | -0.0239937 |
| ADIPOR2 | adiponectin receptor 2 | -0.0239006 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0237709 |
