| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.195504 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0845974 |
| PTMA | prothymosin, alpha | 0.0836097 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 0.0779087 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0756445 |
| CCND1 | cyclin D1 | 0.0722339 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0710483 |
| TFRC | transferrin receptor | 0.0709483 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0699149 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0679689 |
| EGR1 | early growth response 1 | 0.0678333 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0619108 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0564996 |
| DIAPH1 | diaphanous-related formin 1 | 0.0552769 |
| TOP1 | topoisomerase (DNA) I | 0.0546356 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0540875 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0509451 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0501432 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0479131 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0478608 |
| RCOR1 | REST corepressor 1 | 0.0470675 |
| ANLN | anillin, actin binding protein | 0.0444983 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0433113 |
| LDHA | lactate dehydrogenase A | 0.0419774 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0414833 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0401001 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0393118 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0383493 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0382498 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0375976 |
| ATP13A3 | ATPase type 13A3 | 0.036734 |
| SIK3 | SIK family kinase 3 | 0.0367003 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0363976 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.03559 |
| RBP1 | retinol binding protein 1, cellular | 0.0348867 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0347911 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0347868 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0344483 |
| CBFB | core-binding factor, beta subunit | 0.0344288 |
| COBL | cordon-bleu WH2 repeat protein | 0.0342349 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0340811 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0340457 |
| NUP58 | nucleoporin 58 | 0.0337684 |
| KRT18 | keratin 18, type I | 0.0335183 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.033228 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0330635 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0325832 |
| MKI67 | marker of proliferation Ki-67 | 0.0320903 |
| IPO7 | importin 7 | 0.0317777 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0312861 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0312383 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0309905 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0298421 |
| MEMO1 | mediator of cell motility 1 | 0.0297341 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0292739 |
| SON | SON DNA binding protein | 0.0289318 |
| JUN | jun proto-oncogene | 0.0286617 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0284573 |
| MED13 | mediator complex subunit 13 | 0.0284407 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0280351 |
| CCNL1 | cyclin L1 | 0.0273268 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0272899 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0268838 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0262871 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0262447 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0258649 |
| GPR137B | G protein-coupled receptor 137B | 0.0258126 |
| SPAG9 | sperm associated antigen 9 | 0.0256984 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0255568 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0252499 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0250625 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0249651 |
| TMSB10 | thymosin beta 10 | 0.0247904 |
| ZNF207 | zinc finger protein 207 | 0.0247217 |
| POTEF | POTE ankyrin domain family, member F | 0.0241855 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0241818 |
| RBM25 | RNA binding motif protein 25 | 0.0236556 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0236171 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0235001 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0233284 |
| KRT8 | keratin 8, type II | 0.0231222 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0230795 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.023028 |
| YY1 | YY1 transcription factor | 0.0225949 |
| PSPC1 | paraspeckle component 1 | 0.0223983 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0223595 |
| ACTG1 | actin gamma 1 | 0.0222597 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0219872 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0218943 |
| LMNA | lamin A/C | 0.0217034 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0215106 |
| EP300 | E1A binding protein p300 | 0.0215102 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.021279 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0212505 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.021232 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0211571 |
| SQSTM1 | sequestosome 1 | 0.0211367 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0210663 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0209891 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0209817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126846 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.11405 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.091164 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0853751 |
| SYT1 | synaptotagmin I | -0.0827457 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0808551 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0773944 |
| ATXN1 | ataxin 1 | -0.0731886 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0658709 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0637377 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0634903 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0576043 |
| DST | dystonin | -0.0570871 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0556715 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0548636 |
| SBF2 | SET binding factor 2 | -0.0491261 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0487269 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0482775 |
| RUNX1 | runt-related transcription factor 1 | -0.0482639 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0480927 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0474306 |
| OXR1 | oxidation resistance 1 | -0.0472975 |
| KIZ | kizuna centrosomal protein | -0.0457101 |
| UTRN | utrophin | -0.0443977 |
| DSPP | dentin sialophosphoprotein | -0.0437395 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.042331 |
| MORF4L2 | mortality factor 4 like 2 | -0.0421475 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0418123 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0416291 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0416226 |
| PDE8A | phosphodiesterase 8A | -0.0416145 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0410669 |
| EZR | ezrin | -0.040305 |
| PROX1 | prospero homeobox 1 | -0.0402764 |
| AOPEP | aminopeptidase O (putative) | -0.0398323 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0397668 |
| ABHD2 | abhydrolase domain containing 2 | -0.0396843 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0392176 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0391363 |
| TXNIP | thioredoxin interacting protein | -0.0388103 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0380036 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0379338 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0376162 |
| RPS6 | ribosomal protein S6 | -0.0372731 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0372344 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0362691 |
| NDRG1 | N-myc downstream regulated 1 | -0.0361724 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0355558 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0354798 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0352915 |
| PHF21A | PHD finger protein 21A | -0.0352503 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0350774 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0350711 |
| SMYD3 | SET and MYND domain containing 3 | -0.0344029 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0344018 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0341924 |
| PRELID2 | PRELI domain containing 2 | -0.0341846 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0341565 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.033397 |
| PTEN | phosphatase and tensin homolog | -0.0333629 |
| TNS3 | tensin 3 | -0.0331772 |
| CANX | calnexin | -0.0330303 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0329615 |
| HDAC8 | histone deacetylase 8 | -0.0328299 |
| PGK1 | phosphoglycerate kinase 1 | -0.0323435 |
| EFNB2 | ephrin-B2 | -0.032053 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0317752 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0314902 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0312332 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0311231 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0310374 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0307016 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.03052 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0302451 |
| HDAC4 | histone deacetylase 4 | -0.0302441 |
| WWOX | WW domain containing oxidoreductase | -0.0302078 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0300703 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0299796 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0298133 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0297996 |
| COG5 | component of oligomeric golgi complex 5 | -0.029669 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0296084 |
| LMO7 | LIM domain 7 | -0.0295034 |
| ZNF638 | zinc finger protein 638 | -0.0294048 |
| RPS3 | ribosomal protein S3 | -0.0292683 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0290514 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0287255 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0285446 |
| FOXP1 | forkhead box P1 | -0.0282433 |
| GOLGB1 | golgin B1 | -0.0282134 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0281845 |
| UBAC2 | UBA domain containing 2 | -0.0279889 |
| RPL7 | ribosomal protein L7 | -0.0278768 |
| GOLGA4 | golgin A4 | -0.0276769 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | -0.0276441 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0276271 |
| CCDC82 | coiled-coil domain containing 82 | -0.0275708 |
| YEATS2 | YEATS domain containing 2 | -0.0273108 |
| VGLL4 | vestigial-like family member 4 | -0.0272792 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0270217 |
