| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ouabain (Octahydrate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ouabain (Octahydrate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.21606 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.181707 |
| STC1 | stanniocalcin 1 | 0.161124 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0731916 |
| SPAG9 | sperm associated antigen 9 | 0.0664875 |
| ADM | adrenomedullin | 0.0661699 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0619503 |
| B2M | beta-2-microglobulin | 0.0616736 |
| GOLGA4 | golgin A4 | 0.059302 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.05367 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.052075 |
| FTL | ferritin, light polypeptide | 0.0519669 |
| FAM13A | family with sequence similarity 13, member A | 0.0497822 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0479669 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0476256 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0464144 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0448997 |
| CD44 | CD44 molecule (Indian blood group) | 0.0448449 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0441362 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0418969 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0418753 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0410965 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0399372 |
| PTMA | prothymosin, alpha | 0.0383933 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0377156 |
| MT2A | metallothionein 2A | 0.0369671 |
| YBX3 | Y box binding protein 3 | 0.0363393 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0358392 |
| CALU | calumenin | 0.0353798 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0352611 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0350058 |
| NUP58 | nucleoporin 58 | 0.0340281 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0331762 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0328916 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0313345 |
| FN1 | fibronectin 1 | 0.030774 |
| NDRG1 | N-myc downstream regulated 1 | 0.0302858 |
| USP3 | ubiquitin specific peptidase 3 | 0.0302177 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0301904 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0297372 |
| COPA | coatomer protein complex, subunit alpha | 0.0296672 |
| SETD5 | SET domain containing 5 | 0.029331 |
| ANXA2 | annexin A2 | 0.0287343 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0286211 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0274067 |
| RNF145 | ring finger protein 145 | 0.0271902 |
| WDR45B | WD repeat domain 45B | 0.0263505 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0253929 |
| WAC | WW domain containing adaptor with coiled-coil | 0.025201 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0245163 |
| RASA2 | RAS p21 protein activator 2 | 0.0243341 |
| CRY1 | cryptochrome circadian clock 1 | 0.0241422 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0239225 |
| QKI | QKI, KH domain containing, RNA binding | 0.0238181 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0237813 |
| CLINT1 | clathrin interactor 1 | 0.0235184 |
| LMNA | lamin A/C | 0.0234812 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0233744 |
| LDHA | lactate dehydrogenase A | 0.0232452 |
| RND3 | Rho family GTPase 3 | 0.0231054 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0230053 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0229756 |
| IER3 | immediate early response 3 | 0.022975 |
| DUSP10 | dual specificity phosphatase 10 | 0.0224372 |
| HELZ | helicase with zinc finger | 0.0224369 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0223837 |
| MORF4L2 | mortality factor 4 like 2 | 0.0223679 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0223094 |
| RLF | rearranged L-myc fusion | 0.0220436 |
| BRD2 | bromodomain containing 2 | 0.0220096 |
| TFG | TRK-fused gene | 0.0217691 |
| SUCO | SUN domain containing ossification factor | 0.0217682 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0212194 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0211098 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0211005 |
| CDC27 | cell division cycle 27 | 0.0210076 |
| HLA-B | major histocompatibility complex, class I, B | 0.0206038 |
| SRP54 | signal recognition particle 54kDa | 0.0205868 |
| NBAS | neuroblastoma amplified sequence | 0.0205644 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0205473 |
| UBC | ubiquitin C | 0.0203192 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0199265 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0199079 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0198408 |
| PKM | pyruvate kinase, muscle | 0.019784 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0197214 |
| AHR | aryl hydrocarbon receptor | 0.0196024 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.019545 |
| WTAP | Wilms tumor 1 associated protein | 0.0195084 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.019279 |
| RPS6 | ribosomal protein S6 | 0.0189765 |
| NOP58 | NOP58 ribonucleoprotein | 0.0188732 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0188302 |
| CCNL1 | cyclin L1 | 0.0187504 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0187202 |
| KIF5B | kinesin family member 5B | 0.0184915 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0183079 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.018146 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0181145 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0180581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.21122 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.204379 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.172322 |
| HMGA2 | high mobility group AT-hook 2 | -0.131145 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.104248 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0992205 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0973459 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0900641 |
| COL1A1 | collagen, type I, alpha 1 | -0.0877974 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0783222 |
| NAV1 | neuron navigator 1 | -0.0746874 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0703937 |
| OXR1 | oxidation resistance 1 | -0.0671645 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0662664 |
| ASPH | aspartate beta-hydroxylase | -0.0652589 |
| GLIS3 | GLIS family zinc finger 3 | -0.0650937 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0627896 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0609551 |
| AHNAK | AHNAK nucleoprotein | -0.05926 |
| COL1A2 | collagen, type I, alpha 2 | -0.0589244 |
| FRMD4A | FERM domain containing 4A | -0.0582889 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0574056 |
| MYO10 | myosin X | -0.0567582 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0491776 |
| RAI14 | retinoic acid induced 14 | -0.0437876 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0417476 |
| CDH13 | cadherin 13 | -0.0414042 |
| EGFR | epidermal growth factor receptor | -0.0411441 |
| COL6A1 | collagen, type VI, alpha 1 | -0.038506 |
| VCL | vinculin | -0.0375083 |
| KIAA1549L | KIAA1549-like | -0.0371135 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0370857 |
| DIAPH2 | diaphanous-related formin 2 | -0.036931 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0359814 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0350361 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0334135 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0313682 |
| RAD51B | RAD51 paralog B | -0.0313586 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0305667 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0299621 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0299113 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0296332 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0289751 |
| COL5A1 | collagen, type V, alpha 1 | -0.0281152 |
| MED13L | mediator complex subunit 13-like | -0.0281048 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0278857 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0277582 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0276922 |
| CALD1 | caldesmon 1 | -0.0274798 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0271819 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0271007 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0263447 |
| VCAN | versican | -0.0263379 |
| PRELID2 | PRELI domain containing 2 | -0.0242087 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0238863 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0237576 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0236166 |
| HDAC9 | histone deacetylase 9 | -0.023358 |
| ATXN1 | ataxin 1 | -0.0232953 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0230049 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0226081 |
| CUX1 | cut-like homeobox 1 | -0.0226049 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0221749 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.022089 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0218951 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0218254 |
| PRRX1 | paired related homeobox 1 | -0.0216018 |
| PRSS23 | protease, serine, 23 | -0.0215356 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0212762 |
| CCDC102B | coiled-coil domain containing 102B | -0.0212527 |
| NCKAP5 | NCK-associated protein 5 | -0.0212385 |
| FBN1 | fibrillin 1 | -0.0211398 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0211251 |
| CDK6 | cyclin-dependent kinase 6 | -0.0209658 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0209035 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.020795 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0207604 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.020549 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0199355 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0198789 |
| EXOC4 | exocyst complex component 4 | -0.0197858 |
| NREP | neuronal regeneration related protein | -0.0194431 |
| SMYD3 | SET and MYND domain containing 3 | -0.0193418 |
| INTS6 | integrator complex subunit 6 | -0.0192818 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0192772 |
| EMP1 | epithelial membrane protein 1 | -0.0188508 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0188052 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0187706 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0179219 |
| DGKI | diacylglycerol kinase, iota | -0.0177495 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0177161 |
| PRR16 | proline rich 16 | -0.017686 |
| TTC23L | tetratricopeptide repeat domain 23-like | -0.0176768 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0176209 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0175109 |
| ANO6 | anoctamin 6 | -0.0174158 |
| SBF2 | SET binding factor 2 | -0.0172074 |
| LYST | lysosomal trafficking regulator | -0.016907 |
| RASAL2 | RAS protein activator like 2 | -0.0167224 |
| IPO9 | importin 9 | -0.0166712 |
