Overexertion_Leukocyte_GSE3606 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3606
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Genes

600 genes differentially expressed during Overexertion_Leukocyte_GSE3606 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
MBD4 methyl-CpG binding domain protein 4 3.4529
ANXA1 annexin A1 3.24727
SF3B1 splicing factor 3b, subunit 1, 155kDa 3.19176
AMD1 adenosylmethionine decarboxylase 1 3.1244
AFTPH aftiphilin 3.06764
USP9X ubiquitin specific peptidase 9, X-linked 3.04611
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 3.02383
KPNB1 karyopherin (importin) beta 1 2.97931
PTGES3 prostaglandin E synthase 3 (cytosolic) 2.80919
HIPK1 homeodomain interacting protein kinase 1 2.79381
C6ORF106 chromosome 6 open reading frame 106 2.79008
GOLGB1 golgin B1 2.70591
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.70334
LRMP lymphoid-restricted membrane protein 2.7016
FKBP4 FK506 binding protein 4, 59kDa 2.66486
RAB35 RAB35, member RAS oncogene family 2.65558
GDAP2 ganglioside induced differentiation associated protein 2 2.57874
XKR8 XK, Kell blood group complex subunit-related family, member 8 2.50057
WASF2 WAS protein family, member 2 2.48197
DIAPH1 diaphanous-related formin 1 2.48035
CSNK1D casein kinase 1, delta 2.43455
RBM39 RNA binding motif protein 39 2.41198
MORC3 MORC family CW-type zinc finger 3 2.40855
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.40401
GLA galactosidase, alpha 2.36924
SON SON DNA binding protein 2.36675
ELF4 E74-like factor 4 (ets domain transcription factor) 2.34683
FAM131A family with sequence similarity 131, member A 2.32613
SMG7 SMG7 nonsense mediated mRNA decay factor 2.31101
SH3BP2 SH3-domain binding protein 2 2.30598
CREBBP CREB binding protein 2.28481
FAM63A family with sequence similarity 63, member A 2.28013
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 2.27353
P3H1 prolyl 3-hydroxylase 1 2.22807
RHOB ras homolog family member B 2.21145
TDP2 tyrosyl-DNA phosphodiesterase 2 2.1876
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 2.16479
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 2.15524
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.12801
CHMP1B charged multivesicular body protein 1B 2.11828
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 2.10593
HSPH1 heat shock 105kDa/110kDa protein 1 2.10335
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.09216
SNAP29 synaptosomal-associated protein, 29kDa 2.08873
MARS methionyl-tRNA synthetase 2.06855
CHMP2A charged multivesicular body protein 2A 2.05512
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2.029
KDM5B lysine (K)-specific demethylase 5B 2.02815
PHIP pleckstrin homology domain interacting protein 2.02412
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 2.0241
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 2.00912
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.00205
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.99584
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.97967
YPEL5 yippee-like 5 (Drosophila) 1.97401
VEZF1 vascular endothelial zinc finger 1 1.97298
PHF21A PHD finger protein 21A 1.94461
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.92234
WDR59 WD repeat domain 59 1.91915
ZMPSTE24 zinc metallopeptidase STE24 1.91767
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.90947
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 1.89152
SLC38A2 solute carrier family 38, member 2 1.89117
MOSPD3 motile sperm domain containing 3 1.8725
FXR1 fragile X mental retardation, autosomal homolog 1 1.87033
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.85424
MRPS6 mitochondrial ribosomal protein S6 1.84696
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 1.84639
HECA headcase homolog (Drosophila) 1.83518
TOR1A torsin family 1, member A (torsin A) 1.83192
TAGLN2 transgelin 2 1.83186
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional) 1.82738
ARNT aryl hydrocarbon receptor nuclear translocator 1.81917
AHCTF1 AT hook containing transcription factor 1 1.81907
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.81834
KIAA0100 KIAA0100 1.81653
ZNF281 zinc finger protein 281 1.81468
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 1.79633
USP8 ubiquitin specific peptidase 8 1.78181
STAG2 stromal antigen 2 1.76921
TMEM43 transmembrane protein 43 1.76882
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 1.76557
BRD4 bromodomain containing 4 1.7628
LOC440434 aminopeptidase puromycin sensitive pseudogene 1.76147
MARK3 MAP/microtubule affinity-regulating kinase 3 1.76083
MED25 mediator complex subunit 25 1.75667
IVNS1ABP influenza virus NS1A binding protein 1.75566
THBD thrombomodulin 1.75504
NEK7 NIMA-related kinase 7 1.75286
SEC11A SEC11 homolog A (S. cerevisiae) 1.74231
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.73626
CLPTM1 cleft lip and palate associated transmembrane protein 1 1.73514
MAVS mitochondrial antiviral signaling protein 1.72832
HOMER3 homer scaffolding protein 3 1.7283
HSBP1 heat shock factor binding protein 1 1.71781
CC2D2B coiled-coil and C2 domain containing 2B 1.71399
PRPF6 pre-mRNA processing factor 6 1.71287
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.71229
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.70645
ANGPT1 angiopoietin 1 1.70219
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 1.69429
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.68997
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.68593
IL1RAP interleukin 1 receptor accessory protein 1.68461
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.67921
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 1.67586
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.66965
CDK13 cyclin-dependent kinase 13 1.65327
FNBP1 formin binding protein 1 1.6486
FGL2 fibrinogen-like 2 1.64538
IL1R1 interleukin 1 receptor, type I 1.64464
RARA retinoic acid receptor, alpha 1.63552
DDIT3 DNA-damage-inducible transcript 3 1.62547
HSPA4 heat shock 70kDa protein 4 1.62529
VEGFA vascular endothelial growth factor A 1.62285
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 1.61525
KLF6 Kruppel-like factor 6 1.6138
DYNLT1 dynein, light chain, Tctex-type 1 1.61263
PANK2 pantothenate kinase 2 1.61141
CCNG2 cyclin G2 1.60621
PCLO piccolo presynaptic cytomatrix protein 1.60392
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.60387
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.60274
CSTA cystatin A (stefin A) 1.59508
WWC3 WWC family member 3 1.58238
TMEM33 transmembrane protein 33 1.58183
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.58091
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.57671
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.57573
IFNA7 interferon, alpha 7 1.57438
RNF114 ring finger protein 114 1.56732
STAU1 staufen double-stranded RNA binding protein 1 1.56687
CDH10 cadherin 10, type 2 (T2-cadherin) 1.56341
TIMP2 TIMP metallopeptidase inhibitor 2 1.56089
BICD2 bicaudal D homolog 2 (Drosophila) 1.55812
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.55522
USP15 ubiquitin specific peptidase 15 1.55488
COL17A1 collagen, type XVII, alpha 1 1.55363
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.55272
DYM dymeclin 1.55194
SF3A1 splicing factor 3a, subunit 1, 120kDa 1.55089
BCORL1 BCL6 corepressor-like 1 1.54947
SCAP SREBF chaperone 1.54907
APLP2 amyloid beta (A4) precursor-like protein 2 1.54605
KIAA0226L KIAA0226-like 1.54597
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.5436
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.5372
WIPF1 WAS/WASL interacting protein family, member 1 1.53349
RAB11FIP1 RAB11 family interacting protein 1 (class I) 1.52749
NXF1 nuclear RNA export factor 1 1.52307
RPL22L1 ribosomal protein L22-like 1 1.51619
ATG9A autophagy related 9A 1.51614
NBPF14 neuroblastoma breakpoint family, member 14 1.51556
CCNL1 cyclin L1 1.51316
PARP8 poly (ADP-ribose) polymerase family, member 8 1.51264
YY1AP1 YY1 associated protein 1 1.51178
MOB1A MOB kinase activator 1A 1.50466
NDEL1 nudE neurodevelopment protein 1-like 1 1.50386
CSNK1A1 casein kinase 1, alpha 1 1.50231
ZNF638 zinc finger protein 638 1.49929
RYBP RING1 and YY1 binding protein 1.49812
PRUNE prune exopolyphosphatase 1.49358
MBNL2 muscleblind-like splicing regulator 2 1.49218
PANK4 pantothenate kinase 4 1.49158
TRIP12 thyroid hormone receptor interactor 12 1.48859
ATHL1 ATH1, acid trehalase-like 1 (yeast) 1.4875
INHBA inhibin, beta A 1.48681
GABARAPL1 GABA(A) receptor-associated protein like 1 1.48295
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 1.47975
IER2 immediate early response 2 1.4784
NIPBL Nipped-B homolog (Drosophila) 1.47219
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.46642
MED12 mediator complex subunit 12 1.46566
TPD52L2 tumor protein D52-like 2 1.46315
PPID peptidylprolyl isomerase D 1.459
ARRB1 arrestin, beta 1 1.45429
NPEPPS aminopeptidase puromycin sensitive 1.4538
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 1.45294
TMEM248 transmembrane protein 248 1.45237
BCLAF1 BCL2-associated transcription factor 1 1.45122
ZNF148 zinc finger protein 148 1.44198
ABHD2 abhydrolase domain containing 2 1.43612
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.43552
KLHL24 kelch-like family member 24 1.43348
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 1.43173
ANKRD6 ankyrin repeat domain 6 1.42938
CELF1 CUGBP, Elav-like family member 1 1.42929
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.42638
KIAA0232 KIAA0232 1.42605
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.42294
RABGAP1L RAB GTPase activating protein 1-like 1.42199
WBP1L WW domain binding protein 1-like 1.41733
MFAP1 microfibrillar-associated protein 1 1.4143
MORF4L2 mortality factor 4 like 2 1.41073
KRT36 keratin 36, type I 1.41031
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 1.41007
KAT2B K(lysine) acetyltransferase 2B 1.40815
STIP1 stress-induced phosphoprotein 1 1.4073
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.40543
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 1.40424
FAM49A family with sequence similarity 49, member A 1.40328
LOC100420758 poly(A) binding protein, nuclear 1 pseudogene 1.40043
LYST lysosomal trafficking regulator 1.39971
IGF1R insulin-like growth factor 1 receptor 1.39864
PTPRE protein tyrosine phosphatase, receptor type, E 1.39615
ZNF230 zinc finger protein 230 1.39534
RAB1A RAB1A, member RAS oncogene family 1.39491
TMBIM1 transmembrane BAX inhibitor motif containing 1 1.39466
NUPL1 nucleoporin like 1 1.39134
NIT1 nitrilase 1 1.39057
MBP myelin basic protein 1.38109
IQSEC1 IQ motif and Sec7 domain 1 1.37405
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 1.3729
LPGAT1 lysophosphatidylglycerol acyltransferase 1 1.36406
REST RE1-silencing transcription factor 1.35934
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 1.35755
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.35371
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.35028
WDR47 WD repeat domain 47 1.34849
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 1.34487
SELPLG selectin P ligand 1.34313
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.34291
ANO10 anoctamin 10 1.34182
WDR45 WD repeat domain 45 1.34051
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 1.33909
ELF1 E74-like factor 1 (ets domain transcription factor) 1.33552
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 1.33358
GAB2 GRB2-associated binding protein 2 1.33252
DNAH7 dynein, axonemal, heavy chain 7 1.33038
CAMKV CaM kinase-like vesicle-associated 1.32005
BIRC2 baculoviral IAP repeat containing 2 1.31832
LINC00483 long intergenic non-protein coding RNA 483 1.31699
DCTN4 dynactin 4 (p62) 1.3129
FASTKD5 FAST kinase domains 5 1.31084
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 1.30925
RAB22A RAB22A, member RAS oncogene family 1.3092
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.30913
ADRA2A adrenoceptor alpha 2A 1.30791
FAM63B family with sequence similarity 63, member B 1.30753
NBR1 neighbor of BRCA1 gene 1 1.30641
TM9SF2 transmembrane 9 superfamily member 2 1.30596
PRL prolactin 1.30578
TMBIM6 transmembrane BAX inhibitor motif containing 6 1.30472
SUMO4 small ubiquitin-like modifier 4 1.30137
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 1.29235
WNK1 WNK lysine deficient protein kinase 1 1.28979
HSPA8 heat shock 70kDa protein 8 1.28804
GATAD2A GATA zinc finger domain containing 2A 1.28522
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 1.28333
HEXIM1 hexamethylene bis-acetamide inducible 1 1.28156
TMEM140 transmembrane protein 140 1.28035
TREM1 triggering receptor expressed on myeloid cells 1 1.27968
RNF111 ring finger protein 111 1.2792
GLTP glycolipid transfer protein 1.27861
CLIC1 chloride intracellular channel 1 1.27714
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 1.27664
CACFD1 calcium channel flower domain containing 1 1.27612
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.2749
MEFV Mediterranean fever 1.27318
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.27188
NSFL1C NSFL1 (p97) cofactor (p47) 1.26933
TOP1 topoisomerase (DNA) I 1.26853
TXNRD2 thioredoxin reductase 2 1.26491
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 1.26089
NCOA3 nuclear receptor coactivator 3 1.26072
GMCL1 germ cell-less, spermatogenesis associated 1 1.26005
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 1.25912
LGI3 leucine-rich repeat LGI family, member 3 1.25698
TMED5 transmembrane emp24 protein transport domain containing 5 1.25106
SH3GL1 SH3-domain GRB2-like 1 1.2495
PQBP1 polyglutamine binding protein 1 1.24784
ELF2 E74-like factor 2 (ets domain transcription factor) 1.24763
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 1.2453
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.2452
GAK cyclin G associated kinase 1.24296
MAP2K4 mitogen-activated protein kinase kinase 4 1.24225
MAP7D1 MAP7 domain containing 1 1.24085
RHOH ras homolog family member H 1.23753
KAT6A K(lysine) acetyltransferase 6A 1.23733
SP3 Sp3 transcription factor 1.23663
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 1.23599
CARHSP1 calcium regulated heat stable protein 1, 24kDa 1.23545
ITPKC inositol-trisphosphate 3-kinase C 1.234
RBM22 RNA binding motif protein 22 1.23393
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 1.2302
BATF3 basic leucine zipper transcription factor, ATF-like 3 1.22998
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1.22975
SETD1B SET domain containing 1B 1.22967
SLC35A5 solute carrier family 35, member A5 1.229
RALBP1 ralA binding protein 1 1.2274
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 1.22098
HDC histidine decarboxylase 1.22073
NFE2 nuclear factor, erythroid 2 1.21954
STRN striatin, calmodulin binding protein 1.21827
ZNF676 zinc finger protein 676 1.20805
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.20343
UIMC1 ubiquitin interaction motif containing 1 1.20294
PRR14 proline rich 14 1.20087
SNX27 sorting nexin family member 27 1.19866
PRDM10 PR domain containing 10 1.19837

decreased expression

Symbol Name Standardized Value
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.18632
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -3.87829
TRIT1 tRNA isopentenyltransferase 1 -3.36677
GOLGA4 golgin A4 -3.26283
TIAF1 TGFB1-induced anti-apoptotic factor 1 -3.1976
UVRAG UV radiation resistance associated -3.16997
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -3.15335
GOLGA5 golgin A5 -3.13971
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) -3.1369
TPI1 triosephosphate isomerase 1 -3.03299
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -3.00109
SFPQ splicing factor proline/glutamine-rich -2.93718
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -2.92342
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -2.91093
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -2.90627
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.88563
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.85148
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -2.84859
PARP6 poly (ADP-ribose) polymerase family, member 6 -2.72828
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -2.71242
RIOK3 RIO kinase 3 -2.69614
YLPM1 YLP motif containing 1 -2.66899
ERGIC3 ERGIC and golgi 3 -2.6537
EAPP E2F-associated phosphoprotein -2.6382
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.61678
CCNH cyclin H -2.58723
GSTP1 glutathione S-transferase pi 1 -2.57794
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -2.55764
SURF1 surfeit 1 -2.55338
BSDC1 BSD domain containing 1 -2.51158
OPA1 optic atrophy 1 (autosomal dominant) -2.4991
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -2.47806
POU2F2 POU class 2 homeobox 2 -2.4517
C18ORF8 chromosome 18 open reading frame 8 -2.42685
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.42444
IGSF1 immunoglobulin superfamily, member 1 -2.4125
PEX19 peroxisomal biogenesis factor 19 -2.40345
CUEDC2 CUE domain containing 2 -2.37838
GOLGA1 golgin A1 -2.36942
CNOT7 CCR4-NOT transcription complex, subunit 7 -2.35638
PDE12 phosphodiesterase 12 -2.34078
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -2.33895
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.3383
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.33814
CASP6 caspase 6, apoptosis-related cysteine peptidase -2.32516
TBCB tubulin folding cofactor B -2.31418
MRPL23 mitochondrial ribosomal protein L23 -2.30818
NUP153 nucleoporin 153kDa -2.30588
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -2.29959
CD40 CD40 molecule, TNF receptor superfamily member 5 -2.29061
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -2.28727
SRP9 signal recognition particle 9kDa -2.28679
HMG20A high mobility group 20A -2.27151
SNW1 SNW domain containing 1 -2.26845
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -2.26539
CCDC90B coiled-coil domain containing 90B -2.25899
EXOC1 exocyst complex component 1 -2.254
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) -2.24048
COX7B cytochrome c oxidase subunit VIIb -2.21524
TMEM87A transmembrane protein 87A -2.20269
WDR61 WD repeat domain 61 -2.20216
MRPL11 mitochondrial ribosomal protein L11 -2.1947
ADSS adenylosuccinate synthase -2.19078
THAP1 THAP domain containing, apoptosis associated protein 1 -2.17548
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -2.16525
PLAA phospholipase A2-activating protein -2.15517
CLUAP1 clusterin associated protein 1 -2.15434
RBMX2 RNA binding motif protein, X-linked 2 -2.15263
TRAPPC2L trafficking protein particle complex 2-like -2.14026
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -2.13195
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.13191
HNRNPK heterogeneous nuclear ribonucleoprotein K -2.12139
N4BP3 NEDD4 binding protein 3 -2.11894
CIRBP cold inducible RNA binding protein -2.11699
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -2.11452
TCTN3 tectonic family member 3 -2.1099
SPAG7 sperm associated antigen 7 -2.10967
PPAT phosphoribosyl pyrophosphate amidotransferase -2.10219
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.09814
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -2.0919
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.08722
KCTD5 potassium channel tetramerization domain containing 5 -2.08282
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) -2.08059
CSNK2B casein kinase 2, beta polypeptide -2.07062
TNIP2 TNFAIP3 interacting protein 2 -2.06365
NUTF2 nuclear transport factor 2 -2.06074
TP53 tumor protein p53 -2.05992
GARS glycyl-tRNA synthetase -2.05949
SCFD1 sec1 family domain containing 1 -2.05085
RCN1 reticulocalbin 1, EF-hand calcium binding domain -2.04942
STRN4 striatin, calmodulin binding protein 4 -2.04864
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.04612
TOP2B topoisomerase (DNA) II beta 180kDa -2.04536
CNOT1 CCR4-NOT transcription complex, subunit 1 -2.04514
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.04318
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 -2.04277
LIPC lipase, hepatic -2.04094
DOK2 docking protein 2, 56kDa -2.03101
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -2.03081
SRSF9 serine/arginine-rich splicing factor 9 -2.02981
UBXN1 UBX domain protein 1 -2.02751
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.02657
AKAP8 A kinase (PRKA) anchor protein 8 -2.00888
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.00761
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -2.00737
CNPY2 canopy FGF signaling regulator 2 -2.00457
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -2.00269
RNASEH1 ribonuclease H1 -1.99797
FNTA farnesyltransferase, CAAX box, alpha -1.9917
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.98755
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -1.97916
ECD ecdysoneless homolog (Drosophila) -1.97803
CTCF CCCTC-binding factor (zinc finger protein) -1.97582
PDHB pyruvate dehydrogenase (lipoamide) beta -1.97355
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -1.96999
ADO 2-aminoethanethiol (cysteamine) dioxygenase -1.96351
ANGPTL2 angiopoietin-like 2 -1.95813
BCL2L13 BCL2-like 13 (apoptosis facilitator) -1.95747
CAMK1 calcium/calmodulin-dependent protein kinase I -1.95081
TXN2 thioredoxin 2 -1.94806
QRICH1 glutamine-rich 1 -1.94313
KEAP1 kelch-like ECH-associated protein 1 -1.94309
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.93329
KIAA0196 KIAA0196 -1.92965
PCSK5 proprotein convertase subtilisin/kexin type 5 -1.92836
TTF1 transcription termination factor, RNA polymerase I -1.92733
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 -1.9259
ERLIN2 ER lipid raft associated 2 -1.92553
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.91679
MAK16 MAK16 homolog (S. cerevisiae) -1.9134
FRYL FRY-like -1.9116
BANF1 barrier to autointegration factor 1 -1.89895
METTL13 methyltransferase like 13 -1.89779
GOSR2 golgi SNAP receptor complex member 2 -1.89482
ANKMY2 ankyrin repeat and MYND domain containing 2 -1.89115
ZSWIM4 zinc finger, SWIM-type containing 4 -1.88913
GMDS GDP-mannose 4,6-dehydratase -1.88183
AAGAB alpha- and gamma-adaptin binding protein -1.88027
ZNF226 zinc finger protein 226 -1.87356
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -1.86678
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -1.86596
MLH1 mutL homolog 1 -1.86586
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -1.8582
RPL26L1 ribosomal protein L26-like 1 -1.85637
FAM192A family with sequence similarity 192, member A -1.85309
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -1.84478
PFKP phosphofructokinase, platelet -1.8388
CTBP1 C-terminal binding protein 1 -1.83798
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -1.83622
EIF3B eukaryotic translation initiation factor 3, subunit B -1.8361
PHKG2 phosphorylase kinase, gamma 2 (testis) -1.83493
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -1.83482
SIRT3 sirtuin 3 -1.83387
MCM2 minichromosome maintenance complex component 2 -1.83225
SAE1 SUMO1 activating enzyme subunit 1 -1.83214
CRYBG3 beta-gamma crystallin domain containing 3 -1.82849
TXNL1 thioredoxin-like 1 -1.82352
NDUFA4 NDUFA4, mitochondrial complex associated -1.81959
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -1.81925
KRIT1 KRIT1, ankyrin repeat containing -1.81047
AQP2 aquaporin 2 (collecting duct) -1.80828
SNRPG small nuclear ribonucleoprotein polypeptide G -1.80687
PDCD2 programmed cell death 2 -1.80333
RBBP6 retinoblastoma binding protein 6 -1.8026
CHUK conserved helix-loop-helix ubiquitous kinase -1.79611
RAB11FIP2 RAB11 family interacting protein 2 (class I) -1.79011
MTF2 metal response element binding transcription factor 2 -1.78395
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -1.78005
VDAC2 voltage-dependent anion channel 2 -1.77886
SNRPE small nuclear ribonucleoprotein polypeptide E -1.77352
BRD9 bromodomain containing 9 -1.77289
COPS8 COP9 signalosome subunit 8 -1.76537
GPATCH1 G patch domain containing 1 -1.76516
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -1.7638
CCT7 chaperonin containing TCP1, subunit 7 (eta) -1.76314
PASK PAS domain containing serine/threonine kinase -1.76195
TERF2IP telomeric repeat binding factor 2, interacting protein -1.76069
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -1.75629
BRD7 bromodomain containing 7 -1.7525
PIGL phosphatidylinositol glycan anchor biosynthesis, class L -1.7477
RNF126 ring finger protein 126 -1.74299
TMEM106B transmembrane protein 106B -1.74264
ZSCAN4 zinc finger and SCAN domain containing 4 -1.74235
SEC23B Sec23 homolog B (S. cerevisiae) -1.74174
BTG3 BTG family, member 3 -1.74066
POLR1C polymerase (RNA) I polypeptide C, 30kDa -1.73787
ATG13 autophagy related 13 -1.71952
RCN2 reticulocalbin 2, EF-hand calcium binding domain -1.71706
ALG8 ALG8, alpha-1,3-glucosyltransferase -1.70795
FLNA filamin A, alpha -1.70602
EWSR1 EWS RNA-binding protein 1 -1.69912
CCDC59 coiled-coil domain containing 59 -1.69504
PHKB phosphorylase kinase, beta -1.69445
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -1.69074
SYNRG synergin, gamma -1.68981
PRDM4 PR domain containing 4 -1.68444
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -1.68404
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -1.68085
LDHA lactate dehydrogenase A -1.68026
AMZ2 archaelysin family metallopeptidase 2 -1.67922
HDGFRP3 hepatoma-derived growth factor, related protein 3 -1.67735
NGLY1 N-glycanase 1 -1.67104
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -1.67051
TMEM163 transmembrane protein 163 -1.66272
DCTN6 dynactin 6 -1.65727
ATXN10 ataxin 10 -1.65699
RAB28 RAB28, member RAS oncogene family -1.65226
GANAB glucosidase, alpha; neutral AB -1.64938
ZC3H7A zinc finger CCCH-type containing 7A -1.64698
MNT MAX network transcriptional repressor -1.64573
ZNF254 zinc finger protein 254 -1.64323
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene -1.64167
OXA1L oxidase (cytochrome c) assembly 1-like -1.63624
RFX5 regulatory factor X, 5 (influences HLA class II expression) -1.6343
UFD1L ubiquitin fusion degradation 1 like (yeast) -1.62899
NOLC1 nucleolar and coiled-body phosphoprotein 1 -1.62814
ADAP2 ArfGAP with dual PH domains 2 -1.6281
ERCC5 excision repair cross-complementation group 5 -1.62797
MEPCE methylphosphate capping enzyme -1.62727
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -1.61938
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -1.61477
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.61309
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -1.61165
CLEC16A C-type lectin domain family 16, member A -1.60797
HAUS7 HAUS augmin-like complex, subunit 7 -1.60627
ATG5 autophagy related 5 -1.60427
SSB Sjogren syndrome antigen B (autoantigen La) -1.60182
C17ORF70 chromosome 17 open reading frame 70 -1.59794
CD200 CD200 molecule -1.59616
TMEM9B TMEM9 domain family, member B -1.5958
FNBP1L formin binding protein 1-like -1.59577
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d -1.59537
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -1.59427
NNT nicotinamide nucleotide transhydrogenase -1.5942
RNF139 ring finger protein 139 -1.59365
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 -1.59231
FDPS farnesyl diphosphate synthase -1.59116
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -1.58798
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -1.58408
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -1.58389
FAM114A1 family with sequence similarity 114, member A1 -1.58349
TIAM1 T-cell lymphoma invasion and metastasis 1 -1.58229
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -1.58173
CRBN cereblon -1.57771
NDC80 NDC80 kinetochore complex component -1.57467
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -1.57439
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -1.5731
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -1.57157
SYNJ2BP synaptojanin 2 binding protein -1.57075
WDR82 WD repeat domain 82 -1.56936
UNC50 unc-50 homolog (C. elegans) -1.56661
CES2 carboxylesterase 2 -1.56651
MRPS31 mitochondrial ribosomal protein S31 -1.56397
NTAN1 N-terminal asparagine amidase -1.55829
CYB561D2 cytochrome b561 family, member D2 -1.55262
ZNF528 zinc finger protein 528 -1.5503
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -1.54882
SECISBP2 SECIS binding protein 2 -1.54741
RBM42 RNA binding motif protein 42 -1.54532
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -1.54468
PUM1 pumilio RNA-binding family member 1 -1.54428
GATAD1 GATA zinc finger domain containing 1 -1.54375
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked -1.53751
CUZD1 CUB and zona pellucida-like domains 1 -1.53593
BBS1 Bardet-Biedl syndrome 1 -1.53404
COPZ1 coatomer protein complex, subunit zeta 1 -1.53351
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -1.5318
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) -1.53137
ZFP37 ZFP37 zinc finger protein -1.52911
EBAG9 estrogen receptor binding site associated, antigen, 9 -1.52788
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -1.52573
RNF14 ring finger protein 14 -1.5236
CCDC109B coiled-coil domain containing 109B -1.52197
C5ORF22 chromosome 5 open reading frame 22 -1.52128
NRBP1 nuclear receptor binding protein 1 -1.52104
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -1.51864
IL1F10 interleukin 1 family, member 10 (theta) -1.51537
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -1.51517
CSK c-src tyrosine kinase -1.51454
ESD esterase D -1.51441
VAMP5 vesicle-associated membrane protein 5 -1.51425
ZNF318 zinc finger protein 318 -1.50908
ACP2 acid phosphatase 2, lysosomal -1.50866
MSMO1 methylsterol monooxygenase 1 -1.50547
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E -1.50525
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -1.50237
COMMD4 COMM domain containing 4 -1.50116
AP5M1 adaptor-related protein complex 5, mu 1 subunit -1.4999
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.49859
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -1.49569
ZNF274 zinc finger protein 274 -1.49448
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -1.49174
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -1.49013
DCTN3 dynactin 3 (p22) -1.48893
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -1.48836
NOP14 NOP14 nucleolar protein -1.4882
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -1.48537
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -1.48216
EP400 E1A binding protein p400 -1.48072
WBSCR22 Williams Beuren syndrome chromosome region 22 -1.47537
Funding