| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaliplatin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.306774 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.142645 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.11103 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.107514 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.107292 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.101872 |
| FLNA | filamin A, alpha | 0.0943086 |
| PLEC | plectin | 0.0926973 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0922665 |
| COL5A1 | collagen, type V, alpha 1 | 0.0903926 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0898035 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0896249 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0861581 |
| CD44 | CD44 molecule (Indian blood group) | 0.0838922 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0802959 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0802407 |
| APP | amyloid beta (A4) precursor protein | 0.07439 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0721201 |
| NAV1 | neuron navigator 1 | 0.0693968 |
| MSN | moesin | 0.0656305 |
| DST | dystonin | 0.0652958 |
| HLA-B | major histocompatibility complex, class I, B | 0.0621318 |
| PLAT | plasminogen activator, tissue | 0.0618699 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0615593 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0579013 |
| TMSB4X | thymosin beta 4, X-linked | 0.0565271 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0563899 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0563647 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0553902 |
| RNF213 | ring finger protein 213 | 0.0552592 |
| CALR | calreticulin | 0.0544306 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0537261 |
| LDHA | lactate dehydrogenase A | 0.0527566 |
| TPM3 | tropomyosin 3 | 0.0522114 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0519045 |
| SEPTIN9 | septin 9 | 0.0515352 |
| MT2A | metallothionein 2A | 0.0511015 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0508128 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0503434 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0495474 |
| DBN1 | drebrin 1 | 0.0481021 |
| CDH13 | cadherin 13 | 0.0468238 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0460291 |
| NONO | non-POU domain containing, octamer-binding | 0.04601 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0442275 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0438448 |
| FLNB | filamin B, beta | 0.0419788 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0419679 |
| HDAC9 | histone deacetylase 9 | 0.0416655 |
| PLXNA2 | plexin A2 | 0.0415376 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0404109 |
| SMAD3 | SMAD family member 3 | 0.0403426 |
| SON | SON DNA binding protein | 0.040342 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0396873 |
| CENPF | centromere protein F, 350/400kDa | 0.0393591 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0392199 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0375406 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0374614 |
| HLA-C | major histocompatibility complex, class I, C | 0.0372729 |
| RRM2 | ribonucleotide reductase M2 | 0.0363416 |
| PFKP | phosphofructokinase, platelet | 0.0363319 |
| ASPH | aspartate beta-hydroxylase | 0.0355117 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0352671 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0350163 |
| RUNX1 | runt-related transcription factor 1 | 0.0340776 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0338222 |
| PKM | pyruvate kinase, muscle | 0.0334551 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0333451 |
| FSTL1 | follistatin-like 1 | 0.0329484 |
| ADAR | adenosine deaminase, RNA-specific | 0.0324672 |
| B2M | beta-2-microglobulin | 0.0323756 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0323123 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0322723 |
| SET | SET nuclear proto-oncogene | 0.0319704 |
| ACTN1 | actinin, alpha 1 | 0.0310355 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0309245 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0302974 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0300986 |
| HRNR | hornerin | 0.0299792 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0294992 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0294305 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0292742 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0291894 |
| ACTG1 | actin gamma 1 | 0.02852 |
| TRABD2B | TraB domain containing 2B | 0.028434 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0281681 |
| MINK1 | misshapen-like kinase 1 | 0.0276391 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0271195 |
| GSE1 | Gse1 coiled-coil protein | 0.0269889 |
| FAT1 | FAT atypical cadherin 1 | 0.0266892 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0265921 |
| FUS | FUS RNA binding protein | 0.0265068 |
| CEP250 | centrosomal protein 250kDa | 0.0260423 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0259295 |
| GLIS3 | GLIS family zinc finger 3 | 0.0259054 |
| BSG | basigin (Ok blood group) | 0.0258092 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0257223 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0255445 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.025501 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0254047 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.21896 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.20721 |
| VIM | vimentin | -0.165576 |
| LOX | lysyl oxidase | -0.125697 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0980047 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.075871 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0752825 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0626509 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0580741 |
| S100A10 | S100 calcium binding protein A10 | -0.0550444 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0540485 |
| CSTB | cystatin B (stefin B) | -0.053927 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0535837 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0486739 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0466701 |
| FBN1 | fibrillin 1 | -0.046047 |
| CD99 | CD99 molecule | -0.0439084 |
| MYADM | myeloid-associated differentiation marker | -0.0435259 |
| MAP4 | microtubule-associated protein 4 | -0.0404633 |
| CCND1 | cyclin D1 | -0.0399549 |
| COL3A1 | collagen, type III, alpha 1 | -0.0365076 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0364246 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0360614 |
| AHNAK | AHNAK nucleoprotein | -0.0354505 |
| GOLGA4 | golgin A4 | -0.0347363 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0346461 |
| FN1 | fibronectin 1 | -0.0343601 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0339933 |
| PTMA | prothymosin, alpha | -0.0332642 |
| S100A6 | S100 calcium binding protein A6 | -0.0322935 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0318996 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0314273 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0305699 |
| SBF2 | SET binding factor 2 | -0.0305119 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0300643 |
| CANX | calnexin | -0.029933 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0291349 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0287599 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0287182 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0285205 |
| MMP12 | matrix metallopeptidase 12 | -0.0284765 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0283927 |
| INSIG1 | insulin induced gene 1 | -0.0277403 |
| SUCNR1 | succinate receptor 1 | -0.0270448 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0263576 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0258076 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0257542 |
| UBC | ubiquitin C | -0.0254171 |
| THBS2 | thrombospondin 2 | -0.0243869 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0239132 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0237912 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0233499 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0230201 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0229624 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0218328 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0214417 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0208459 |
| GNAS | GNAS complex locus | -0.0203802 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0203787 |
| FNIP1 | folliculin interacting protein 1 | -0.0203682 |
| LOXL2 | lysyl oxidase-like 2 | -0.0203388 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0202253 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0199331 |
| ZNF292 | zinc finger protein 292 | -0.0198153 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.019713 |
| COL1A2 | collagen, type I, alpha 2 | -0.0196162 |
| RPS15 | ribosomal protein S15 | -0.0195796 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0194004 |
| THY1 | Thy-1 cell surface antigen | -0.0191858 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0191018 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0189193 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0188218 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0187697 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0186631 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0185644 |
| LRRC17 | leucine rich repeat containing 17 | -0.0185297 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0183041 |
| RTN4 | reticulon 4 | -0.0181169 |
| NBEAL1 | neurobeachin-like 1 | -0.0179993 |
| CD109 | CD109 molecule | -0.0178645 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0175625 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0175421 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0174695 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0172359 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0171654 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0170068 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0169933 |
| CDK13 | cyclin-dependent kinase 13 | -0.016958 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0167292 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0167051 |
| KRT81 | keratin 81, type II | -0.0166628 |
| HIP1 | huntingtin interacting protein 1 | -0.0163263 |
| TMEM263 | transmembrane protein 263 | -0.0162884 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0160845 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0160597 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0160507 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0160152 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.015961 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0159191 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0159185 |
