| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaliplatin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.16162 |
| NLGN1 | neuroligin 1 | 0.131735 |
| YAP1 | Yes-associated protein 1 | 0.12319 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.112934 |
| RRM2 | ribonucleotide reductase M2 | 0.112293 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.112223 |
| HMGA2 | high mobility group AT-hook 2 | 0.110359 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.105957 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.104344 |
| PCDH7 | protocadherin 7 | 0.103869 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0970108 |
| DST | dystonin | 0.0939294 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0797309 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0706434 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0691841 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.068432 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0663651 |
| TMSB10 | thymosin beta 10 | 0.0658222 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0610486 |
| LDHA | lactate dehydrogenase A | 0.0591484 |
| WWOX | WW domain containing oxidoreductase | 0.0577846 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.057073 |
| INTS6 | integrator complex subunit 6 | 0.0570218 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0541354 |
| FTL | ferritin, light polypeptide | 0.0536672 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0514396 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0513817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0512551 |
| CMIP | c-Maf inducing protein | 0.0506827 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0500588 |
| TENM3 | teneurin transmembrane protein 3 | 0.0499794 |
| ASPH | aspartate beta-hydroxylase | 0.0499279 |
| CALR | calreticulin | 0.0491956 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0481433 |
| CCN2 | cellular communication network factor 2 | 0.0472359 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0469151 |
| CPNE1 | copine I | 0.0464884 |
| AREG | amphiregulin | 0.0462891 |
| CLTC | clathrin, heavy chain (Hc) | 0.0460745 |
| ADIPOR2 | adiponectin receptor 2 | 0.0459437 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0456889 |
| FUS | FUS RNA binding protein | 0.0456416 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0448544 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0445271 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0441554 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.043566 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0435169 |
| DENND5A | DENN/MADD domain containing 5A | 0.043372 |
| ATP11A | ATPase, class VI, type 11A | 0.043342 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0432259 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.042606 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0422691 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0421013 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0416456 |
| NONO | non-POU domain containing, octamer-binding | 0.0415907 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0415865 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0409354 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0405975 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0404288 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.040333 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0398695 |
| MKI67 | marker of proliferation Ki-67 | 0.0397568 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.039665 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0396461 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0391237 |
| TPI1 | triosephosphate isomerase 1 | 0.0387473 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0386898 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0383835 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0378879 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0378529 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.03736 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0369424 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0362358 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0360494 |
| FLNA | filamin A, alpha | 0.0359065 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0358902 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0355388 |
| EXOC4 | exocyst complex component 4 | 0.0352126 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0351823 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0349251 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0348694 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0344866 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0343932 |
| PDGFC | platelet derived growth factor C | 0.0336729 |
| CANX | calnexin | 0.0336037 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0332521 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0330827 |
| HELLS | helicase, lymphoid-specific | 0.0330047 |
| PRKCE | protein kinase C, epsilon | 0.0329889 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.03296 |
| MED13L | mediator complex subunit 13-like | 0.0323196 |
| TEAD4 | TEA domain family member 4 | 0.0321639 |
| RPS19 | ribosomal protein S19 | 0.0320325 |
| RPL31 | ribosomal protein L31 | 0.0319066 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0318226 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.031739 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0309595 |
| ETV6 | ets variant 6 | 0.0309353 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0308808 |
| RAD51B | RAD51 paralog B | 0.0306446 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101349 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0652944 |
| HMGA1 | high mobility group AT-hook 1 | -0.0381216 |
| EHBP1 | EH domain binding protein 1 | -0.0369865 |
| PTMS | parathymosin | -0.0352258 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0334808 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0258161 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0235337 |
| RBM25 | RNA binding motif protein 25 | -0.0218491 |
| KLHL24 | kelch-like family member 24 | -0.021371 |
| CLDN1 | claudin 1 | -0.02095 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0207559 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.020423 |
| MMP12 | matrix metallopeptidase 12 | -0.0200647 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0198783 |
| BCHE | butyrylcholinesterase | -0.0198489 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0197855 |
| VIM | vimentin | -0.0197178 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0195287 |
| SLC38A2 | solute carrier family 38, member 2 | -0.019016 |
| WDR43 | WD repeat domain 43 | -0.018806 |
| HSPB1 | heat shock 27kDa protein 1 | -0.018646 |
| TSPAN5 | tetraspanin 5 | -0.018645 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0185901 |
| ZFR | zinc finger RNA binding protein | -0.0183131 |
| WASF2 | WAS protein family, member 2 | -0.01829 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.018114 |
| SBF2 | SET binding factor 2 | -0.01724 |
| FBXO11 | F-box protein 11 | -0.0170349 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0168421 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0167602 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0163934 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0163876 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0161814 |
| TMEM123 | transmembrane protein 123 | -0.0160767 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.015956 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0158345 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0157353 |
| S100A6 | S100 calcium binding protein A6 | -0.0157304 |
| THOC2 | THO complex 2 | -0.0156906 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0156358 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0156132 |
| PRR11 | proline rich 11 | -0.0153769 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0151425 |
| JMJD1C | jumonji domain containing 1C | -0.0148852 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | -0.0148206 |
| NABP1 | nucleic acid binding protein 1 | -0.0146131 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0145451 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0145163 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0143641 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0143582 |
| CCNL1 | cyclin L1 | -0.0143512 |
| RPS2 | ribosomal protein S2 | -0.0141678 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0141092 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0140477 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0140073 |
| NUP58 | nucleoporin 58 | -0.0138957 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0136778 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0136709 |
| MGAT4C | MGAT4 family, member C | -0.0136609 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0136265 |
| PREPL | prolyl endopeptidase-like | -0.0136091 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0134276 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | -0.0133994 |
| PTMA | prothymosin, alpha | -0.0132171 |
| PRKCI | protein kinase C, iota | -0.0131319 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0130833 |
| DTNA | dystrobrevin, alpha | -0.012922 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.012773 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0126286 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0126209 |
| SESN2 | sestrin 2 | -0.0126156 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0126075 |
| LMO7 | LIM domain 7 | -0.012578 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0125499 |
| S100A10 | S100 calcium binding protein A10 | -0.0124804 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0123481 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0122091 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0121484 |
| MAP4 | microtubule-associated protein 4 | -0.0120934 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0120347 |
| RPL8 | ribosomal protein L8 | -0.0120054 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0119583 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0119284 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.011844 |
| MYADM | myeloid-associated differentiation marker | -0.0118064 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0116377 |
| FNBP4 | formin binding protein 4 | -0.0116291 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.011554 |
| CCNI | cyclin I | -0.0114278 |
| MTREX | Mtr4 exosome RNA helicase | -0.0113037 |
| FOXK2 | forkhead box K2 | -0.0111615 |
| KIF18B | kinesin family member 18B | -0.0111247 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0111166 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0110579 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0110186 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0109891 |
| WDR75 | WD repeat domain 75 | -0.0109186 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0108462 |
| ZNF652 | zinc finger protein 652 | -0.0107828 |
