| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Oxaliplatin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.34163 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.204744 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.126222 |
| C3 | complement component 3 | 0.123193 |
| MT2A | metallothionein 2A | 0.118065 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.113221 |
| SVIL | supervillin | 0.11041 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.110332 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.110197 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.106994 |
| KRT8 | keratin 8, type II | 0.0910697 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0875229 |
| DSPP | dentin sialophosphoprotein | 0.0875118 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0842517 |
| VEGFA | vascular endothelial growth factor A | 0.0756493 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0755464 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0700642 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0666919 |
| RPL3 | ribosomal protein L3 | 0.0643379 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0635421 |
| TNS1 | tensin 1 | 0.0627059 |
| BCL2L1 | BCL2-like 1 | 0.0624352 |
| FAM107B | family with sequence similarity 107, member B | 0.0588074 |
| PLEC | plectin | 0.0587966 |
| FAT1 | FAT atypical cadherin 1 | 0.0586223 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0558156 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0557985 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0547341 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0546585 |
| ACTN4 | actinin, alpha 4 | 0.0518357 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0483721 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0465933 |
| DST | dystonin | 0.0461318 |
| FOXP1 | forkhead box P1 | 0.0423179 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0412973 |
| KRT18 | keratin 18, type I | 0.0411461 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0405684 |
| TPM1 | tropomyosin 1 (alpha) | 0.0403371 |
| ACTG1 | actin gamma 1 | 0.0402707 |
| KYNU | kynureninase | 0.0393372 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0391237 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0390874 |
| ACTN1 | actinin, alpha 1 | 0.0380256 |
| FLNA | filamin A, alpha | 0.037275 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0370298 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0367269 |
| SMAD3 | SMAD family member 3 | 0.0361442 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0359907 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0350585 |
| LDHA | lactate dehydrogenase A | 0.0335742 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0335621 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0334816 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0331636 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.03281 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0323475 |
| VCL | vinculin | 0.0321624 |
| NONO | non-POU domain containing, octamer-binding | 0.0321525 |
| POTEF | POTE ankyrin domain family, member F | 0.0318212 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.031723 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0312685 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0306812 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0302819 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0299733 |
| SFTPA2 | surfactant protein A2 | 0.0294908 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0290485 |
| CEP250 | centrosomal protein 250kDa | 0.0288337 |
| TMSB10 | thymosin beta 10 | 0.0287416 |
| JUN | jun proto-oncogene | 0.0281106 |
| OPTN | optineurin | 0.0278471 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0277316 |
| KIAA1217 | KIAA1217 | 0.0276313 |
| BRD4 | bromodomain containing 4 | 0.0275705 |
| ITGB5 | integrin, beta 5 | 0.0275179 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0274849 |
| CORO1C | coronin, actin binding protein, 1C | 0.0273588 |
| PCBP2 | poly(rC) binding protein 2 | 0.0272344 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0272271 |
| PEG3 | paternally expressed 3 | 0.0272256 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0270252 |
| DIAPH1 | diaphanous-related formin 1 | 0.0269996 |
| ALPK2 | alpha-kinase 2 | 0.0269511 |
| SEPTIN9 | septin 9 | 0.0266319 |
| CLTB | clathrin, light chain B | 0.0262755 |
| DIDO1 | death inducer-obliterator 1 | 0.0261492 |
| CCN2 | cellular communication network factor 2 | 0.0260961 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0260511 |
| SDC4 | syndecan 4 | 0.0259286 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0259073 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0258696 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0256658 |
| SEPTIN2 | septin 2 | 0.0255494 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.025244 |
| CMIP | c-Maf inducing protein | 0.0251361 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.025062 |
| FN1 | fibronectin 1 | 0.0247468 |
| ATXN1 | ataxin 1 | 0.0241773 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0239624 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0237465 |
| RNF43 | ring finger protein 43 | 0.0237332 |
| ITGAV | integrin, alpha V | 0.0233312 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.227536 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.112918 |
| GPC3 | glypican 3 | -0.112516 |
| EHBP1 | EH domain binding protein 1 | -0.110469 |
| FNDC3B | fibronectin type III domain containing 3B | -0.10897 |
| CP | ceruloplasmin (ferroxidase) | -0.0924821 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0843542 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0816152 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0768917 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0727635 |
| GPC6 | glypican 6 | -0.0699584 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0666759 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0622189 |
| GNAS | GNAS complex locus | -0.0610304 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0607057 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.060421 |
| RPS24 | ribosomal protein S24 | -0.0582513 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0560185 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0533641 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0529835 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0519819 |
| TMEM123 | transmembrane protein 123 | -0.0518416 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0494827 |
| AHSG | alpha-2-HS-glycoprotein | -0.0484056 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.047343 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0468139 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0467426 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0466613 |
| FMNL2 | formin-like 2 | -0.0460539 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0456629 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0454898 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0454452 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0450451 |
| GK | glycerol kinase | -0.0442797 |
| DTNA | dystrobrevin, alpha | -0.0416809 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0410935 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0400075 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.039264 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0390303 |
| RBM39 | RNA binding motif protein 39 | -0.038764 |
| RPS27A | ribosomal protein S27a | -0.0375961 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0345849 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0340279 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0336081 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0333743 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0331846 |
| PHF3 | PHD finger protein 3 | -0.0329477 |
| RPL34 | ribosomal protein L34 | -0.0328462 |
| IER3 | immediate early response 3 | -0.0326691 |
| RPL35A | ribosomal protein L35a | -0.0320551 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0314188 |
| NPR2 | natriuretic peptide receptor 2 | -0.0313749 |
| PARD3 | par-3 family cell polarity regulator | -0.0307735 |
| INTS6 | integrator complex subunit 6 | -0.0302834 |
| RPS8 | ribosomal protein S8 | -0.0299777 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0298753 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0296911 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0292326 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0289425 |
| RYBP | RING1 and YY1 binding protein | -0.0287981 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0283611 |
| RPL26 | ribosomal protein L26 | -0.028168 |
| MYO6 | myosin VI | -0.0280408 |
| RPL31 | ribosomal protein L31 | -0.0276776 |
| TRIM26 | tripartite motif containing 26 | -0.0276305 |
| QKI | QKI, KH domain containing, RNA binding | -0.0272011 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0269384 |
| STK17A | serine/threonine kinase 17a | -0.0268526 |
| RPL37A | ribosomal protein L37a | -0.0268395 |
| ZNF292 | zinc finger protein 292 | -0.0264067 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0261154 |
| RPL9 | ribosomal protein L9 | -0.0258888 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.025415 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | -0.0250952 |
| WDR45B | WD repeat domain 45B | -0.0250268 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0250071 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.024637 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0243761 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0235123 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0234599 |
| RPS25 | ribosomal protein S25 | -0.0228337 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0227889 |
| RPL5 | ribosomal protein L5 | -0.0227743 |
| RPLP2 | ribosomal protein, large, P2 | -0.0225169 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0225127 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0224324 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0223185 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0221026 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0220774 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0219686 |
| A2M | alpha-2-macroglobulin | -0.0218588 |
| JMJD1C | jumonji domain containing 1C | -0.0218479 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0218471 |
| SBF2 | SET binding factor 2 | -0.0217131 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0216777 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0211624 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0210558 |
| TMEM263 | transmembrane protein 263 | -0.0210527 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.020961 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0209236 |
