| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaliplatin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.162807 |
| FAT1 | FAT atypical cadherin 1 | 0.156604 |
| KRT8 | keratin 8, type II | 0.14209 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.127868 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.107668 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0965388 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0846856 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0830422 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0822422 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0802626 |
| KRT18 | keratin 18, type I | 0.0763999 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0741377 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0738165 |
| MYO1E | myosin IE | 0.0726659 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0720052 |
| VCL | vinculin | 0.0688913 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0656506 |
| ACTG1 | actin gamma 1 | 0.0632731 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0566867 |
| ASPH | aspartate beta-hydroxylase | 0.0543748 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.054067 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0539547 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0538949 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0531286 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0521113 |
| EGFR | epidermal growth factor receptor | 0.0489277 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0480471 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0479921 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0475625 |
| SMYD3 | SET and MYND domain containing 3 | 0.0466783 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0466439 |
| PLEC | plectin | 0.0452916 |
| FHIT | fragile histidine triad | 0.0444066 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0438018 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0420859 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0419471 |
| EPHB2 | EPH receptor B2 | 0.039751 |
| RPL3 | ribosomal protein L3 | 0.0395865 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0395615 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0394958 |
| CTBP2 | C-terminal binding protein 2 | 0.0381317 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0370727 |
| TPM1 | tropomyosin 1 (alpha) | 0.0366334 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0364147 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0361258 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0360019 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0358091 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.035731 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0356288 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0353476 |
| VEGFA | vascular endothelial growth factor A | 0.0350843 |
| MLEC | malectin | 0.0348455 |
| RAD51B | RAD51 paralog B | 0.0347783 |
| ABR | active BCR-related | 0.034132 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0334241 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0328807 |
| NONO | non-POU domain containing, octamer-binding | 0.0318867 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.031672 |
| SVIL | supervillin | 0.0316086 |
| CMIP | c-Maf inducing protein | 0.0315775 |
| CALR | calreticulin | 0.0315334 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0314089 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0310264 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0308092 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0307426 |
| ECT2 | epithelial cell transforming 2 | 0.0306607 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0303046 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0302102 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0302039 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0294091 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0293846 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0292811 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.029161 |
| HDAC4 | histone deacetylase 4 | 0.0284909 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0280915 |
| TMSB4X | thymosin beta 4, X-linked | 0.0280569 |
| FLNA | filamin A, alpha | 0.0280101 |
| MYO5B | myosin VB | 0.0277317 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0274899 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0273354 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0267086 |
| CENPF | centromere protein F, 350/400kDa | 0.02668 |
| INTS6 | integrator complex subunit 6 | 0.0266179 |
| ACTN4 | actinin, alpha 4 | 0.0265793 |
| SEPTIN9 | septin 9 | 0.0263913 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0262921 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0260843 |
| CADPS | Ca++-dependent secretion activator | 0.02594 |
| EXOC4 | exocyst complex component 4 | 0.0259054 |
| SMAD3 | SMAD family member 3 | 0.0258623 |
| WWOX | WW domain containing oxidoreductase | 0.0256616 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0256425 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0255727 |
| TUBA1B | tubulin, alpha 1b | 0.0250835 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0250689 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0250556 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0248735 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.024786 |
| APP | amyloid beta (A4) precursor protein | 0.0246607 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0245454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.27407 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.186822 |
| PTMA | prothymosin, alpha | -0.154376 |
| GOLGA4 | golgin A4 | -0.0883682 |
| NDRG1 | N-myc downstream regulated 1 | -0.0836585 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0774762 |
| TXNIP | thioredoxin interacting protein | -0.0711312 |
| FAM13A | family with sequence similarity 13, member A | -0.0651247 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0639883 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0620845 |
| ANXA2 | annexin A2 | -0.0540245 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0528233 |
| ZNF292 | zinc finger protein 292 | -0.0496187 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0495148 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0482132 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0479869 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0474371 |
| WDR45B | WD repeat domain 45B | -0.0460849 |
| EREG | epiregulin | -0.0454664 |
| RPS6 | ribosomal protein S6 | -0.0442815 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0439864 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0412694 |
| RBM39 | RNA binding motif protein 39 | -0.0399445 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0398834 |
| GDF15 | growth differentiation factor 15 | -0.0387306 |
| PRSS3 | protease, serine, 3 | -0.0385029 |
| TMSB10 | thymosin beta 10 | -0.0384795 |
| HMGA1 | high mobility group AT-hook 1 | -0.0377903 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0376703 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0372482 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0365873 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0364207 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0362796 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0357639 |
| OGA | O-GlcNAcase | -0.0353554 |
| EXOC1 | exocyst complex component 1 | -0.0351587 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0350006 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0349941 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0341835 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0341126 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0341069 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0339775 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0338857 |
| FNBP1L | formin binding protein 1-like | -0.0335885 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0333119 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0332541 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0326937 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0323892 |
| SBF2 | SET binding factor 2 | -0.0323034 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0320856 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0318837 |
| USP3 | ubiquitin specific peptidase 3 | -0.0315282 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0314568 |
| COG5 | component of oligomeric golgi complex 5 | -0.0312838 |
| NPSR1 | neuropeptide S receptor 1 | -0.0310706 |
| RPL12 | ribosomal protein L12 | -0.0310695 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0308641 |
| RNF145 | ring finger protein 145 | -0.0305123 |
| S100A6 | S100 calcium binding protein A6 | -0.0303575 |
| WASF2 | WAS protein family, member 2 | -0.030283 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0296727 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0291309 |
| RPL34 | ribosomal protein L34 | -0.0291044 |
| CALB1 | calbindin 1, 28kDa | -0.028876 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0287841 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0286055 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0285196 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0282312 |
| INSIG1 | insulin induced gene 1 | -0.0281964 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0281191 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0280775 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0280083 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0275927 |
| NF1 | neurofibromin 1 | -0.0272182 |
| TFG | TRK-fused gene | -0.0267797 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0267236 |
| S100A10 | S100 calcium binding protein A10 | -0.0267196 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0264475 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0262594 |
| RPS8 | ribosomal protein S8 | -0.0261586 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0260767 |
| AGR2 | anterior gradient 2 | -0.0260235 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.025927 |
| CD2AP | CD2-associated protein | -0.0258154 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0258084 |
| RPL18 | ribosomal protein L18 | -0.0253229 |
| PGK1 | phosphoglycerate kinase 1 | -0.0250997 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0250583 |
| SPAG9 | sperm associated antigen 9 | -0.0249199 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0247962 |
| CCNI | cyclin I | -0.0246514 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0246187 |
| RPL32 | ribosomal protein L32 | -0.0242503 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239803 |
| RLF | rearranged L-myc fusion | -0.0239378 |
| SRP54 | signal recognition particle 54kDa | -0.0237493 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0237212 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0237095 |
| RPS23 | ribosomal protein S23 | -0.0235555 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.023177 |
