| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Oxaliplatin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.17794 |
| DST | dystonin | 0.142455 |
| TP63 | tumor protein p63 | 0.127612 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.114515 |
| MT2A | metallothionein 2A | 0.107281 |
| HLA-B | major histocompatibility complex, class I, B | 0.0864704 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.085405 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0818336 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0792432 |
| CAPRIN2 | caprin family member 2 | 0.0764295 |
| DPYD | dihydropyrimidine dehydrogenase | 0.068457 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0682908 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0676053 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0675175 |
| CADM2 | cell adhesion molecule 2 | 0.0663509 |
| FMNL2 | formin-like 2 | 0.0645119 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0616594 |
| RNF213 | ring finger protein 213 | 0.0614268 |
| RAD51B | RAD51 paralog B | 0.0550106 |
| CD44 | CD44 molecule (Indian blood group) | 0.0542241 |
| POTEF | POTE ankyrin domain family, member F | 0.0535301 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0508639 |
| CMIP | c-Maf inducing protein | 0.0502745 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0495836 |
| PDE10A | phosphodiesterase 10A | 0.0495357 |
| PRELID2 | PRELI domain containing 2 | 0.0490475 |
| SP100 | SP100 nuclear antigen | 0.0483268 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0481911 |
| DNER | delta/notch-like EGF repeat containing | 0.0475473 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.047 |
| TGM2 | transglutaminase 2 | 0.0464661 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0448781 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0440252 |
| RUNX1 | runt-related transcription factor 1 | 0.0439845 |
| RIGI | RNA sensor RIG-I | 0.0437043 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0433904 |
| VCL | vinculin | 0.0408095 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0406908 |
| EXOC4 | exocyst complex component 4 | 0.0405378 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0398476 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0396794 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0395032 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0393784 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0383828 |
| PODXL | podocalyxin-like | 0.0382883 |
| TNS3 | tensin 3 | 0.0380155 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0370204 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0369676 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.036649 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0355227 |
| SMYD3 | SET and MYND domain containing 3 | 0.035082 |
| ENO1 | enolase 1, (alpha) | 0.0349622 |
| SMAD3 | SMAD family member 3 | 0.0346976 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.034691 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0338306 |
| RPS12 | ribosomal protein S12 | 0.0332857 |
| MT1E | metallothionein 1E | 0.0326002 |
| RPL31 | ribosomal protein L31 | 0.0324824 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0314977 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0314765 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0313618 |
| TMSB4X | thymosin beta 4, X-linked | 0.0313484 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0311998 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0308414 |
| ECE1 | endothelin converting enzyme 1 | 0.0305944 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0305566 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0300046 |
| PRKCE | protein kinase C, epsilon | 0.0298543 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0296554 |
| HLA-A | major histocompatibility complex, class I, A | 0.0293664 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0293647 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0290959 |
| INTS6 | integrator complex subunit 6 | 0.0290617 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0285646 |
| SDC4 | syndecan 4 | 0.0283684 |
| NONO | non-POU domain containing, octamer-binding | 0.0281785 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0281774 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0281356 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0279502 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0278079 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0276979 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0275975 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0274478 |
| PKM | pyruvate kinase, muscle | 0.0271959 |
| B2M | beta-2-microglobulin | 0.0271084 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0268388 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0267982 |
| WDR27 | WD repeat domain 27 | 0.0267489 |
| PLEC | plectin | 0.0267094 |
| RPL37 | ribosomal protein L37 | 0.0266996 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0266403 |
| MOK | MOK protein kinase | 0.0266052 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0266019 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0265778 |
| NEK10 | NIMA-related kinase 10 | 0.026557 |
| RPL37A | ribosomal protein L37a | 0.0265523 |
| RPL35A | ribosomal protein L35a | 0.0261384 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0257795 |
| PTK2 | protein tyrosine kinase 2 | 0.0255264 |
| RPS17 | ribosomal protein S17 | 0.0251988 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21874 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.164295 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.11907 |
| TXNRD1 | thioredoxin reductase 1 | -0.094674 |
| PTMA | prothymosin, alpha | -0.0766251 |
| VIM | vimentin | -0.0695463 |
| RAI1 | retinoic acid induced 1 | -0.0649728 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0574847 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0536929 |
| CANX | calnexin | -0.0532251 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0478384 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0421916 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0406481 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0404813 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0354554 |
| KLF6 | Kruppel-like factor 6 | -0.0313796 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0302408 |
| EZR | ezrin | -0.0292521 |
| SRGN | serglycin | -0.0292028 |
| GOLGA4 | golgin A4 | -0.0291272 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0290158 |
| ANXA1 | annexin A1 | -0.0286898 |
| WDR45B | WD repeat domain 45B | -0.0282947 |
| AHNAK | AHNAK nucleoprotein | -0.0278424 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0275612 |
| JMJD1C | jumonji domain containing 1C | -0.0263267 |
| EREG | epiregulin | -0.0256415 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0252576 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0249033 |
| TMEM41B | transmembrane protein 41B | -0.0243765 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0241671 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0235 |
| RTN4 | reticulon 4 | -0.0233118 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0212323 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0205942 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0205036 |
| TMEM123 | transmembrane protein 123 | -0.0201954 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0200603 |
| RBM39 | RNA binding motif protein 39 | -0.019935 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.019735 |
| UBC | ubiquitin C | -0.0194455 |
| ZFR | zinc finger RNA binding protein | -0.0193623 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0193233 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0192483 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0190395 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0187801 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0184203 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0181359 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0180131 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0178317 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0178073 |
| ZNF292 | zinc finger protein 292 | -0.0176863 |
| UPP1 | uridine phosphorylase 1 | -0.0173929 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0173104 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0171453 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0171152 |
| SBF2 | SET binding factor 2 | -0.0168662 |
| KLHL24 | kelch-like family member 24 | -0.0168291 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0168086 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0166653 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0166109 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0165165 |
| WASF2 | WAS protein family, member 2 | -0.0164067 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0163258 |
| CALR | calreticulin | -0.0161185 |
| YME1L1 | YME1-like 1 ATPase | -0.0161055 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.015969 |
| HMGA1 | high mobility group AT-hook 1 | -0.0159386 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0158115 |
| EMP1 | epithelial membrane protein 1 | -0.0157885 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0157079 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0156676 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0152393 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0152318 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0151131 |
| SRP72 | signal recognition particle 72kDa | -0.0150997 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0150685 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0150371 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0149401 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0149381 |
| S100A10 | S100 calcium binding protein A10 | -0.0149266 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0147447 |
| ZNF217 | zinc finger protein 217 | -0.014624 |
| RIOK3 | RIO kinase 3 | -0.0144381 |
| SEPTIN7 | septin 7 | -0.0143349 |
| CENPF | centromere protein F, 350/400kDa | -0.014303 |
| MORF4L2 | mortality factor 4 like 2 | -0.0142818 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0142696 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0142113 |
| RLF | rearranged L-myc fusion | -0.0141941 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0141673 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.014065 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.014035 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0139877 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0138857 |
| RASAL2 | RAS protein activator like 2 | -0.0138701 |
| NOP58 | NOP58 ribonucleoprotein | -0.013785 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0135976 |
| CD2AP | CD2-associated protein | -0.0135551 |
| MAP4 | microtubule-associated protein 4 | -0.0135051 |
