| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaliplatin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT17 | keratin 17, type I | 0.156613 |
| EGFR | epidermal growth factor receptor | 0.124429 |
| DSCAM | Down syndrome cell adhesion molecule | 0.121598 |
| IGF1R | insulin-like growth factor 1 receptor | 0.114078 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.109875 |
| MYO5B | myosin VB | 0.107993 |
| MYO1E | myosin IE | 0.107218 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.106081 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.105475 |
| LMO7 | LIM domain 7 | 0.104708 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0995793 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0957553 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0936162 |
| KYNU | kynureninase | 0.0926633 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0887285 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0816851 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.081537 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0808482 |
| MUC16 | mucin 16, cell surface associated | 0.0761069 |
| TXNRD1 | thioredoxin reductase 1 | 0.0760782 |
| ANXA2 | annexin A2 | 0.0752858 |
| SPAG9 | sperm associated antigen 9 | 0.0739839 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0729797 |
| MCL1 | myeloid cell leukemia 1 | 0.0727476 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0711841 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0694241 |
| LDHA | lactate dehydrogenase A | 0.0678428 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0659681 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0656548 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0654841 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0648666 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0646776 |
| ATXN1 | ataxin 1 | 0.0644944 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0642747 |
| RPL31 | ribosomal protein L31 | 0.0632223 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.062703 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0615162 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0614608 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0610175 |
| LAMC2 | laminin, gamma 2 | 0.060999 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0605298 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0603368 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0592954 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.058286 |
| FAT1 | FAT atypical cadherin 1 | 0.0581968 |
| EZR | ezrin | 0.0572044 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0563775 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0562863 |
| MSN | moesin | 0.05494 |
| FOXO3 | forkhead box O3 | 0.0532899 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0532841 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0516261 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0514196 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0513775 |
| RPL23 | ribosomal protein L23 | 0.0503537 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0494988 |
| CMIP | c-Maf inducing protein | 0.0487874 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0485167 |
| BPTF | bromodomain PHD finger transcription factor | 0.0473545 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0465653 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0464969 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0463067 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0463038 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.046216 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0456755 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0447639 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0447579 |
| GSK3B | glycogen synthase kinase 3 beta | 0.044657 |
| ABHD3 | abhydrolase domain containing 3 | 0.0431237 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0430442 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0427045 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0426182 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0424267 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0423708 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0418439 |
| NCOR2 | nuclear receptor corepressor 2 | 0.041812 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0415909 |
| RPL35A | ribosomal protein L35a | 0.0411469 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0408673 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.040845 |
| FMNL2 | formin-like 2 | 0.0407888 |
| BRD4 | bromodomain containing 4 | 0.0406844 |
| FGF13 | fibroblast growth factor 13 | 0.0401225 |
| RPL15 | ribosomal protein L15 | 0.0400212 |
| FRMD4A | FERM domain containing 4A | 0.0399661 |
| RPS13 | ribosomal protein S13 | 0.0399502 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0397704 |
| VEGFA | vascular endothelial growth factor A | 0.039762 |
| LAMB3 | laminin, beta 3 | 0.0395306 |
| TJP1 | tight junction protein 1 | 0.0390888 |
| SET | SET nuclear proto-oncogene | 0.0390685 |
| DSTN | destrin (actin depolymerizing factor) | 0.0378994 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0374037 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0370777 |
| USP53 | ubiquitin specific peptidase 53 | 0.03697 |
| SIK3 | SIK family kinase 3 | 0.0369404 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0362994 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0359537 |
| RPS25 | ribosomal protein S25 | 0.035895 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0355829 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.119037 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.107106 |
| FNDC3B | fibronectin type III domain containing 3B | -0.104595 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0991519 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0966287 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0964156 |
| VIM | vimentin | -0.0878327 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0870367 |
| CD44 | CD44 molecule (Indian blood group) | -0.083879 |
| MMP1 | matrix metallopeptidase 1 | -0.0808525 |
| MT2A | metallothionein 2A | -0.0806252 |
| NDRG1 | N-myc downstream regulated 1 | -0.0797386 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0752147 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.074623 |
| LOXL2 | lysyl oxidase-like 2 | -0.0733731 |
| METTL15 | methyltransferase like 15 | -0.072959 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0720681 |
| OGA | O-GlcNAcase | -0.0698773 |
| PRKCA | protein kinase C, alpha | -0.0696631 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0696582 |
| AK1 | adenylate kinase 1 | -0.0657488 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0635242 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0628973 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0626099 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0622438 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.061835 |
| MAP4 | microtubule-associated protein 4 | -0.0617053 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0603791 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0580853 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0580512 |
| RASA2 | RAS p21 protein activator 2 | -0.0575719 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0572078 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0572074 |
| ASPH | aspartate beta-hydroxylase | -0.0571706 |
| SEPTIN10 | septin 10 | -0.0571287 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0568854 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0563947 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0562601 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0560406 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0558258 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0557022 |
| JMJD1C | jumonji domain containing 1C | -0.055684 |
| KLF6 | Kruppel-like factor 6 | -0.0553104 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0537813 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0536507 |
| FTL | ferritin, light polypeptide | -0.0536293 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0536255 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0533109 |
| HPCAL1 | hippocalcin-like 1 | -0.0529914 |
| ZNF638 | zinc finger protein 638 | -0.0526225 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0524107 |
| RPS19 | ribosomal protein S19 | -0.0523073 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0522054 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0506327 |
| FRMD5 | FERM domain containing 5 | -0.0505451 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0503613 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0497793 |
| RORA | RAR-related orphan receptor A | -0.049415 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0493749 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0485349 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0484753 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0481703 |
| FLNB | filamin B, beta | -0.0474607 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0466251 |
| GLIS3 | GLIS family zinc finger 3 | -0.046292 |
| APP | amyloid beta (A4) precursor protein | -0.0459094 |
| CA12 | carbonic anhydrase XII | -0.0456247 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0452334 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0447684 |
| C1D | C1D nuclear receptor corepressor | -0.0444773 |
| GNAS | GNAS complex locus | -0.0440434 |
| TMEM165 | transmembrane protein 165 | -0.0437689 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0432051 |
| ATP13A3 | ATPase type 13A3 | -0.0428012 |
| PKM | pyruvate kinase, muscle | -0.0427825 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.042485 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0422707 |
| FAM13A | family with sequence similarity 13, member A | -0.0420606 |
| CDK17 | cyclin-dependent kinase 17 | -0.0420596 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0419818 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0418971 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0417978 |
| RBM47 | RNA binding motif protein 47 | -0.0413883 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0411521 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0411285 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0411176 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0410301 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0409937 |
| RSF1 | remodeling and spacing factor 1 | -0.0406837 |
| NF1 | neurofibromin 1 | -0.0406047 |
| EHBP1 | EH domain binding protein 1 | -0.0399984 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0397762 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0396595 |
| RPS11 | ribosomal protein S11 | -0.0392748 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0390437 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0386785 |
| SQSTM1 | sequestosome 1 | -0.038472 |
| RTN4 | reticulon 4 | -0.0382838 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0382614 |
| SMYD3 | SET and MYND domain containing 3 | -0.0377523 |
