| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaliplatin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.182895 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.163567 |
| GRAMD1B | GRAM domain containing 1B | 0.108466 |
| YBX3 | Y box binding protein 3 | 0.101443 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0809213 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.078589 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0760827 |
| EGR1 | early growth response 1 | 0.0714329 |
| MCL1 | myeloid cell leukemia 1 | 0.0643601 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0623952 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0581623 |
| PLEC | plectin | 0.053335 |
| INTS6 | integrator complex subunit 6 | 0.0519149 |
| NONO | non-POU domain containing, octamer-binding | 0.0512694 |
| KRT18 | keratin 18, type I | 0.0507189 |
| ACTN1 | actinin, alpha 1 | 0.0502983 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0487758 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0487112 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0484085 |
| HSPA8 | heat shock 70kDa protein 8 | 0.047768 |
| ACTG1 | actin gamma 1 | 0.047744 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0464357 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0454801 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.044333 |
| RPL3 | ribosomal protein L3 | 0.0434674 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0427713 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0424946 |
| AFF3 | AF4/FMR2 family, member 3 | 0.041484 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0412194 |
| TMSB10 | thymosin beta 10 | 0.0411077 |
| ATP11A | ATPase, class VI, type 11A | 0.0410734 |
| HOMER1 | homer scaffolding protein 1 | 0.0403557 |
| CPNE1 | copine I | 0.0402071 |
| WWOX | WW domain containing oxidoreductase | 0.0400108 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0394083 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0388695 |
| AEBP2 | AE binding protein 2 | 0.0383803 |
| POTEF | POTE ankyrin domain family, member F | 0.0381137 |
| TPM3 | tropomyosin 3 | 0.0378886 |
| TPM2 | tropomyosin 2 (beta) | 0.0374226 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0368181 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0362195 |
| PRKCE | protein kinase C, epsilon | 0.0355687 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0355193 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0352413 |
| TLN1 | talin 1 | 0.035065 |
| FLNA | filamin A, alpha | 0.0350208 |
| KRT8 | keratin 8, type II | 0.0349148 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0348905 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0348701 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0347738 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0345421 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0345417 |
| MEF2D | myocyte enhancer factor 2D | 0.0344586 |
| SMAD3 | SMAD family member 3 | 0.0336341 |
| COPA | coatomer protein complex, subunit alpha | 0.033623 |
| HDAC4 | histone deacetylase 4 | 0.0335551 |
| FUS | FUS RNA binding protein | 0.0328092 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0325378 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0323376 |
| DIDO1 | death inducer-obliterator 1 | 0.0322414 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.032109 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0318453 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0315017 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0312511 |
| CEP250 | centrosomal protein 250kDa | 0.031235 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0308701 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0308552 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0307249 |
| INTS1 | integrator complex subunit 1 | 0.0306851 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0299103 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0298698 |
| PRELID3B | PRELI domain containing 3B | 0.0298222 |
| SEPTIN2 | septin 2 | 0.0294192 |
| VCL | vinculin | 0.0289765 |
| CMIP | c-Maf inducing protein | 0.0287141 |
| BRD4 | bromodomain containing 4 | 0.0284207 |
| RNF213 | ring finger protein 213 | 0.02837 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0283464 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0283226 |
| HYOU1 | hypoxia up-regulated 1 | 0.0282819 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0282729 |
| PFKP | phosphofructokinase, platelet | 0.0282454 |
| BRD2 | bromodomain containing 2 | 0.0278212 |
| MSN | moesin | 0.0276514 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0275962 |
| RBM19 | RNA binding motif protein 19 | 0.0273746 |
| PCBP2 | poly(rC) binding protein 2 | 0.0270771 |
| FMNL2 | formin-like 2 | 0.0269655 |
| JUN | jun proto-oncogene | 0.0268441 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0268324 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.026727 |
| ZYX | zyxin | 0.0262754 |
| YAP1 | Yes-associated protein 1 | 0.0260981 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0260791 |
| HLA-B | major histocompatibility complex, class I, B | 0.0259838 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0259123 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0258191 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0257284 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0255294 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.199278 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.140018 |
| TXNRD1 | thioredoxin reductase 1 | -0.0840333 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0743752 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0627019 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0563362 |
| RTN4 | reticulon 4 | -0.0530931 |
| BBX | bobby sox homolog (Drosophila) | -0.0528926 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.052388 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0512434 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0511791 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0493766 |
| PHIP | pleckstrin homology domain interacting protein | -0.0493549 |
| XPO1 | exportin 1 | -0.0482308 |
| ZNF292 | zinc finger protein 292 | -0.045813 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0457134 |
| SBF2 | SET binding factor 2 | -0.0449352 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0449328 |
| PTMA | prothymosin, alpha | -0.0444024 |
| ZFR | zinc finger RNA binding protein | -0.0429651 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0423598 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0408529 |
| MKI67 | marker of proliferation Ki-67 | -0.0405441 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.039726 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0393883 |
| CCND2 | cyclin D2 | -0.039109 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.039031 |
| GOLGA4 | golgin A4 | -0.0375145 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0372279 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0361967 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0360702 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0357011 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0353281 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0350788 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0349933 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0348924 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0344027 |
| H1-0 | H1.0 linker histone | -0.0342658 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0327012 |
| PCNX1 | pecanex 1 | -0.0325494 |
| NF1 | neurofibromin 1 | -0.0322719 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0319568 |
| RPS2 | ribosomal protein S2 | -0.0313871 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0311367 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0311255 |
| SEPTIN7 | septin 7 | -0.0308368 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0308285 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0307978 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0306822 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0305755 |
| OGA | O-GlcNAcase | -0.029763 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0293473 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0292509 |
| RASA2 | RAS p21 protein activator 2 | -0.0292188 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0290971 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0290604 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0289912 |
| WDR45B | WD repeat domain 45B | -0.0284664 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.028389 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0281998 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0281051 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0278752 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0275794 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0274539 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.027426 |
| CENPF | centromere protein F, 350/400kDa | -0.027219 |
| RPL12 | ribosomal protein L12 | -0.026986 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0267687 |
| R3HDM1 | R3H domain containing 1 | -0.0266017 |
| RPL26 | ribosomal protein L26 | -0.0265144 |
| SRP72 | signal recognition particle 72kDa | -0.0264695 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0264463 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0262964 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0260339 |
| THOC2 | THO complex 2 | -0.0257765 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0254114 |
| ABI2 | abl-interactor 2 | -0.0253445 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.025295 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0252846 |
| TPI1 | triosephosphate isomerase 1 | -0.0252432 |
| TLK1 | tousled-like kinase 1 | -0.0252375 |
| SRPK1 | SRSF protein kinase 1 | -0.0252096 |
| GPHN | gephyrin | -0.0250632 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0249708 |
| CD2AP | CD2-associated protein | -0.024711 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0245655 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0244988 |
| CCND1 | cyclin D1 | -0.0244309 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0243047 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0242273 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0241333 |
| TPX2 | TPX2, microtubule-associated | -0.0241232 |
| MED13L | mediator complex subunit 13-like | -0.0240596 |
| TNPO3 | transportin 3 | -0.0240436 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0235936 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0233983 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0233947 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0233633 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0233249 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0229904 |
