| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Oxaliplatin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.182153 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.149597 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.126485 |
| PLEC | plectin | 0.113366 |
| NDRG1 | N-myc downstream regulated 1 | 0.0903774 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0818023 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0791303 |
| LAMC2 | laminin, gamma 2 | 0.0759257 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0711733 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0708698 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0689567 |
| TMSB4X | thymosin beta 4, X-linked | 0.0684122 |
| RPL37 | ribosomal protein L37 | 0.0682378 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0680746 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0642787 |
| HLA-B | major histocompatibility complex, class I, B | 0.0631776 |
| RPL35A | ribosomal protein L35a | 0.0616076 |
| SMAD3 | SMAD family member 3 | 0.0559854 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.055754 |
| EFNA5 | ephrin-A5 | 0.0549178 |
| DSPP | dentin sialophosphoprotein | 0.0543798 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0539827 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0532501 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0512935 |
| FTL | ferritin, light polypeptide | 0.051229 |
| RPL23 | ribosomal protein L23 | 0.0485883 |
| NAV2 | neuron navigator 2 | 0.0485721 |
| SDC4 | syndecan 4 | 0.047878 |
| VEGFA | vascular endothelial growth factor A | 0.0466434 |
| NONO | non-POU domain containing, octamer-binding | 0.0455261 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0447215 |
| KRT8 | keratin 8, type II | 0.0446514 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0443372 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0417589 |
| RPL3 | ribosomal protein L3 | 0.0415221 |
| MSN | moesin | 0.0392668 |
| HLA-A | major histocompatibility complex, class I, A | 0.0388277 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0377632 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.037465 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.036315 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0362487 |
| MYO5B | myosin VB | 0.0359733 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0355136 |
| LMO7 | LIM domain 7 | 0.035451 |
| LAMB3 | laminin, beta 3 | 0.0353417 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.034839 |
| RPL9 | ribosomal protein L9 | 0.0348202 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.034516 |
| ATXN1 | ataxin 1 | 0.0343438 |
| EGFR | epidermal growth factor receptor | 0.0342299 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0340454 |
| FLNA | filamin A, alpha | 0.033197 |
| FBXO32 | F-box protein 32 | 0.0320692 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0319065 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0309601 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0307546 |
| RNF213 | ring finger protein 213 | 0.0302231 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0301259 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0297963 |
| SON | SON DNA binding protein | 0.029579 |
| RPL11 | ribosomal protein L11 | 0.0294981 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0294396 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0294181 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0293957 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0292675 |
| INTS6 | integrator complex subunit 6 | 0.0291741 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0287209 |
| SVIL | supervillin | 0.0286699 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0285365 |
| MT2A | metallothionein 2A | 0.0285352 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0281859 |
| DBN1 | drebrin 1 | 0.0274698 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0264487 |
| KRT18 | keratin 18, type I | 0.0264218 |
| ANO6 | anoctamin 6 | 0.0264154 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0263781 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0262905 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.026133 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0255318 |
| RPL13A | ribosomal protein L13a | 0.0254159 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0251007 |
| LDHA | lactate dehydrogenase A | 0.0246649 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0242192 |
| RPS27 | ribosomal protein S27 | 0.0241088 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0239798 |
| ATP11A | ATPase, class VI, type 11A | 0.0239756 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0238171 |
| BRD2 | bromodomain containing 2 | 0.0236404 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0235137 |
| MX1 | MX dynamin-like GTPase 1 | 0.0234844 |
| RPS17 | ribosomal protein S17 | 0.0234247 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0230412 |
| HDAC9 | histone deacetylase 9 | 0.0229862 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0229781 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0228781 |
| DST | dystonin | 0.022822 |
| GOLGA3 | golgin A3 | 0.0227563 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0226117 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0225773 |
| DOCK5 | dedicator of cytokinesis 5 | 0.022522 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.319932 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137662 |
| PTMA | prothymosin, alpha | -0.124289 |
| POTEF | POTE ankyrin domain family, member F | -0.117282 |
| FN1 | fibronectin 1 | -0.105693 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0961593 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.084637 |
| UBC | ubiquitin C | -0.0770957 |
| HMGA1 | high mobility group AT-hook 1 | -0.074565 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0701947 |
| S100A10 | S100 calcium binding protein A10 | -0.0675928 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0661143 |
| RPL8 | ribosomal protein L8 | -0.0643733 |
| RPS23 | ribosomal protein S23 | -0.0639707 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0612596 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.05862 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0583366 |
| TFG | TRK-fused gene | -0.0581237 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0575471 |
| GOLGA4 | golgin A4 | -0.0529326 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0526116 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0497817 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0488482 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0477048 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0472771 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.046123 |
| TOP1 | topoisomerase (DNA) I | -0.0450236 |
| CCND1 | cyclin D1 | -0.0436945 |
| DEK | DEK proto-oncogene | -0.0434174 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0430614 |
| ZNF292 | zinc finger protein 292 | -0.0418214 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0408359 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0402538 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0401013 |
| RNF145 | ring finger protein 145 | -0.039951 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0395004 |
| TMEM123 | transmembrane protein 123 | -0.0393122 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.038517 |
| GNAS | GNAS complex locus | -0.0383219 |
| WASF2 | WAS protein family, member 2 | -0.0380916 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0377403 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0375164 |
| CCNL1 | cyclin L1 | -0.0366229 |
| CCNI | cyclin I | -0.036213 |
| CD2AP | CD2-associated protein | -0.035688 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0350969 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0347917 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0344609 |
| USP3 | ubiquitin specific peptidase 3 | -0.0343184 |
| RLF | rearranged L-myc fusion | -0.0341943 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0340142 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.033528 |
| RBM39 | RNA binding motif protein 39 | -0.033409 |
| SLMAP | sarcolemma associated protein | -0.0332119 |
| RBM25 | RNA binding motif protein 25 | -0.0323911 |
| DSTN | destrin (actin depolymerizing factor) | -0.032211 |
| FAM13A | family with sequence similarity 13, member A | -0.0320857 |
| SETD5 | SET domain containing 5 | -0.0314561 |
| CDC73 | cell division cycle 73 | -0.0313956 |
| RPL32 | ribosomal protein L32 | -0.0312658 |
| ZNF207 | zinc finger protein 207 | -0.0310026 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0306319 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0305605 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0301063 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0299106 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0298699 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0297381 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0293309 |
| TMEM263 | transmembrane protein 263 | -0.0291041 |
| CERT1 | ceramide transporter 1 | -0.0286756 |
| RPS15 | ribosomal protein S15 | -0.0285981 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0284046 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0283655 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0280164 |
| MEF2A | myocyte enhancer factor 2A | -0.0278074 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0276111 |
| RIOK3 | RIO kinase 3 | -0.0272369 |
| UPP1 | uridine phosphorylase 1 | -0.0272067 |
| RPS8 | ribosomal protein S8 | -0.0272032 |
| MAP4 | microtubule-associated protein 4 | -0.0269559 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0269545 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0265629 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0261524 |
| QKI | QKI, KH domain containing, RNA binding | -0.0258987 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0254813 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0254298 |
| HMGB1 | high mobility group box 1 | -0.0252117 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.025203 |
| KLHL24 | kelch-like family member 24 | -0.0251003 |
| CDK17 | cyclin-dependent kinase 17 | -0.0244747 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0243719 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0242081 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0240597 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0239041 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0237884 |
| NOP58 | NOP58 ribonucleoprotein | -0.0235112 |
| AREG | amphiregulin | -0.023509 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0233207 |
| SPAG9 | sperm associated antigen 9 | -0.022858 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0226085 |
