| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaliplatin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.14197 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.125995 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.11681 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.107737 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0980751 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0938117 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0923506 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0920937 |
| ACTG1 | actin gamma 1 | 0.0918311 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0865008 |
| GRAMD1B | GRAM domain containing 1B | 0.0847971 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0818631 |
| FN1 | fibronectin 1 | 0.0772188 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0759822 |
| COL5A1 | collagen, type V, alpha 1 | 0.0747852 |
| ASPH | aspartate beta-hydroxylase | 0.0739592 |
| RAD51B | RAD51 paralog B | 0.0709292 |
| CALU | calumenin | 0.0700834 |
| OXR1 | oxidation resistance 1 | 0.0679045 |
| RCOR1 | REST corepressor 1 | 0.0675492 |
| PLEC | plectin | 0.0620801 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0617795 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0602095 |
| SBF2 | SET binding factor 2 | 0.0599563 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0591392 |
| RPS6 | ribosomal protein S6 | 0.0566757 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0556929 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0556773 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0552385 |
| ENO1 | enolase 1, (alpha) | 0.0543259 |
| B2M | beta-2-microglobulin | 0.0534642 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0528991 |
| CDH13 | cadherin 13 | 0.0517378 |
| VEGFA | vascular endothelial growth factor A | 0.0508578 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0504107 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0501042 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0491452 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.047759 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0470059 |
| HMGA2 | high mobility group AT-hook 2 | 0.0469944 |
| STC1 | stanniocalcin 1 | 0.0465854 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0460211 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0456485 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.045577 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0454959 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0446302 |
| HLA-B | major histocompatibility complex, class I, B | 0.0442298 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.04346 |
| ACTN4 | actinin, alpha 4 | 0.0424715 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.041296 |
| IGF2 | insulin-like growth factor 2 | 0.0392524 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0386722 |
| EGFR | epidermal growth factor receptor | 0.0385928 |
| EXT1 | exostosin glycosyltransferase 1 | 0.036978 |
| PRKCA | protein kinase C, alpha | 0.0363306 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0340221 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0339989 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0338666 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0323943 |
| RNF213 | ring finger protein 213 | 0.0305071 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303503 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0299159 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0296128 |
| LDHA | lactate dehydrogenase A | 0.0292986 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0292099 |
| PCBP2 | poly(rC) binding protein 2 | 0.0284537 |
| EZR | ezrin | 0.0275307 |
| RPLP1 | ribosomal protein, large, P1 | 0.0268655 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0264578 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0263659 |
| MCL1 | myeloid cell leukemia 1 | 0.0225986 |
| VCL | vinculin | 0.0217648 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0208675 |
| BPTF | bromodomain PHD finger transcription factor | 0.0201516 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0199794 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0197481 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0183072 |
| SIK3 | SIK family kinase 3 | 0.0182598 |
| RPLP0 | ribosomal protein, large, P0 | 0.0177079 |
| RPS8 | ribosomal protein S8 | 0.017186 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0162869 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0161672 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0144478 |
| MYOF | myoferlin | 0.0122493 |
| PGK1 | phosphoglycerate kinase 1 | 0.0112808 |
| LMO7 | LIM domain 7 | 0.0111255 |
| MYO1E | myosin IE | 0.0110394 |
| TMSB10 | thymosin beta 10 | 0.0107855 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0106652 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.00930006 |
| RPL37A | ribosomal protein L37a | 0.00874256 |
| RPLP2 | ribosomal protein, large, P2 | 0.00798055 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00741144 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.00411227 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00394552 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00375155 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00302411 |
| ATXN1 | ataxin 1 | 0.00208677 |
| RPS27A | ribosomal protein S27a | 0.00113627 |
| TENT5A | terminal nucleotidyltransferase 5A | 6.05414E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229244 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.187811 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.125902 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.123932 |
| PTK2 | protein tyrosine kinase 2 | -0.112651 |
| VIM | vimentin | -0.109936 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0947938 |
| PTMA | prothymosin, alpha | -0.0923205 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0863348 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0812451 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0768283 |
| RORA | RAR-related orphan receptor A | -0.0733728 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0728973 |
| ITGA6 | integrin, alpha 6 | -0.0697309 |
| ZNF292 | zinc finger protein 292 | -0.0689686 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0681443 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0658344 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0655981 |
| NDRG1 | N-myc downstream regulated 1 | -0.0644164 |
| GPHN | gephyrin | -0.0618039 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0597171 |
| CADM2 | cell adhesion molecule 2 | -0.0593898 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0581733 |
| ANXA2 | annexin A2 | -0.0574576 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0559858 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0551472 |
| SEPTIN2 | septin 2 | -0.0545716 |
| PEG10 | paternally expressed 10 | -0.0543178 |
| USP34 | ubiquitin specific peptidase 34 | -0.0494585 |
| GOLGB1 | golgin B1 | -0.0494399 |
| JMJD1C | jumonji domain containing 1C | -0.0492281 |
| PKM | pyruvate kinase, muscle | -0.048623 |
| ZNF608 | zinc finger protein 608 | -0.047263 |
| ARRDC3 | arrestin domain containing 3 | -0.047203 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0466548 |
| HDLBP | high density lipoprotein binding protein | -0.0463189 |
| RAD21 | RAD21 homolog (S. pombe) | -0.046237 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0447716 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0421879 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0411491 |
| RPL34 | ribosomal protein L34 | -0.0403379 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0398706 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0396619 |
| TOP1 | topoisomerase (DNA) I | -0.038941 |
| FAM13A | family with sequence similarity 13, member A | -0.0372644 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0369404 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0368962 |
| SMYD3 | SET and MYND domain containing 3 | -0.0352649 |
| RPL12 | ribosomal protein L12 | -0.0349823 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.03447 |
| GOLGA4 | golgin A4 | -0.0341515 |
| GPC6 | glypican 6 | -0.0340378 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0339678 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0338676 |
| DNER | delta/notch-like EGF repeat containing | -0.0337858 |
| RPS24 | ribosomal protein S24 | -0.0334882 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0326884 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0319571 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0314021 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0311622 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0309731 |
| LAMB3 | laminin, beta 3 | -0.030036 |
| RPS16 | ribosomal protein S16 | -0.0300326 |
| PHF3 | PHD finger protein 3 | -0.0294899 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0280846 |
| RACK1 | receptor for activated C kinase 1 | -0.0278423 |
| TXNRD1 | thioredoxin reductase 1 | -0.0268566 |
| FTL | ferritin, light polypeptide | -0.0266211 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0261194 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0261192 |
| MT2A | metallothionein 2A | -0.0252686 |
| H3-3B | H3.3 histone B | -0.0242207 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0241234 |
| ATP11A | ATPase, class VI, type 11A | -0.0238386 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0227203 |
| RPL37 | ribosomal protein L37 | -0.0226662 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0215321 |
| RPL11 | ribosomal protein L11 | -0.0200643 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0199007 |
| MED13L | mediator complex subunit 13-like | -0.019785 |
| SETD5 | SET domain containing 5 | -0.0192897 |
| PDE10A | phosphodiesterase 10A | -0.0190189 |
| FMNL2 | formin-like 2 | -0.0188435 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0175383 |
| BBX | bobby sox homolog (Drosophila) | -0.0170327 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0161766 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0156211 |
| SPAG9 | sperm associated antigen 9 | -0.0146075 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0131018 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0130601 |
| DST | dystonin | -0.0129921 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0128542 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0119857 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0106553 |
| CANX | calnexin | -0.0104636 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.00933984 |
| RTN4 | reticulon 4 | -0.00787793 |
| TPM4 | tropomyosin 4 | -0.00706417 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00693984 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.00625858 |
