| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaliplatin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Oxaliplatin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.204282 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.164554 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.116579 |
| SMAD3 | SMAD family member 3 | 0.0965884 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0877737 |
| HLA-B | major histocompatibility complex, class I, B | 0.0874856 |
| HLA-A | major histocompatibility complex, class I, A | 0.0820328 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.066514 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0630932 |
| LDHA | lactate dehydrogenase A | 0.0626376 |
| HMGA2 | high mobility group AT-hook 2 | 0.0603805 |
| GLIS3 | GLIS family zinc finger 3 | 0.059574 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0581006 |
| MT2A | metallothionein 2A | 0.0580082 |
| NONO | non-POU domain containing, octamer-binding | 0.0570684 |
| MLPH | melanophilin | 0.0545587 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0540542 |
| HDAC9 | histone deacetylase 9 | 0.0531345 |
| BICC1 | BicC family RNA binding protein 1 | 0.0505722 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0476007 |
| ASPH | aspartate beta-hydroxylase | 0.0454083 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0443623 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0439682 |
| INTS6 | integrator complex subunit 6 | 0.0438967 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0430221 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0419529 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.041022 |
| VCL | vinculin | 0.0409856 |
| EXT1 | exostosin glycosyltransferase 1 | 0.040675 |
| VEGFA | vascular endothelial growth factor A | 0.0405628 |
| PGK1 | phosphoglycerate kinase 1 | 0.0401169 |
| RPL37 | ribosomal protein L37 | 0.0396264 |
| ATXN1 | ataxin 1 | 0.0381923 |
| RPL35A | ribosomal protein L35a | 0.0380313 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0364527 |
| RPL37A | ribosomal protein L37a | 0.0362493 |
| DST | dystonin | 0.0359947 |
| RPL11 | ribosomal protein L11 | 0.0358466 |
| DUSP10 | dual specificity phosphatase 10 | 0.0358196 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0343347 |
| COL5A1 | collagen, type V, alpha 1 | 0.0333343 |
| FAM20C | family with sequence similarity 20, member C | 0.0328504 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0324603 |
| TMSB4X | thymosin beta 4, X-linked | 0.0323064 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0318432 |
| HLA-C | major histocompatibility complex, class I, C | 0.031247 |
| CEP250 | centrosomal protein 250kDa | 0.0311058 |
| AHNAK | AHNAK nucleoprotein | 0.0307808 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0302169 |
| VCAN | versican | 0.029975 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0296633 |
| RPL9 | ribosomal protein L9 | 0.0295028 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0283597 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0283057 |
| FLNA | filamin A, alpha | 0.0281902 |
| PLEC | plectin | 0.027962 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0279005 |
| RNF213 | ring finger protein 213 | 0.0278356 |
| RPL31 | ribosomal protein L31 | 0.0274217 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0271854 |
| RPL13A | ribosomal protein L13a | 0.0271813 |
| RPLP2 | ribosomal protein, large, P2 | 0.0270243 |
| APP | amyloid beta (A4) precursor protein | 0.0267012 |
| RPL38 | ribosomal protein L38 | 0.0263667 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0257582 |
| RPL23 | ribosomal protein L23 | 0.0257318 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0254488 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0251025 |
| MSN | moesin | 0.0250905 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0250641 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0247504 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0243534 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0242557 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0238616 |
| HLA-E | major histocompatibility complex, class I, E | 0.0230429 |
| ENO1 | enolase 1, (alpha) | 0.0229197 |
| ACTN1 | actinin, alpha 1 | 0.022908 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0227333 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0225914 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0225852 |
| SYNJ2 | synaptojanin 2 | 0.0221818 |
| RPS24 | ribosomal protein S24 | 0.0220461 |
| CPNE1 | copine I | 0.0215475 |
| AFDN | afadin, adherens junction formation factor | 0.0214646 |
| RPS25 | ribosomal protein S25 | 0.0211488 |
| RPS16 | ribosomal protein S16 | 0.0210051 |
| FTL | ferritin, light polypeptide | 0.0209514 |
| ACTG1 | actin gamma 1 | 0.0209036 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0208471 |
| SFTPA2 | surfactant protein A2 | 0.0207955 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0207896 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0207528 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0205318 |
| NAV1 | neuron navigator 1 | 0.0204942 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0194398 |
| SVIL | supervillin | 0.0194302 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.019202 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0190222 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0187859 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0187728 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190678 |
| VIM | vimentin | -0.140223 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.138818 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0795984 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0686626 |
| GOLGA4 | golgin A4 | -0.0535109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.052307 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0504745 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0478719 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0465915 |
| CADM1 | cell adhesion molecule 1 | -0.0451413 |
| JMJD1C | jumonji domain containing 1C | -0.0439066 |
| PTMA | prothymosin, alpha | -0.0438449 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0419736 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0416782 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.04064 |
| ZNF292 | zinc finger protein 292 | -0.0394922 |
| RTN4 | reticulon 4 | -0.0391588 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0389965 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0389212 |
| UBC | ubiquitin C | -0.0368825 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0368576 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0366376 |
| PLIN2 | perilipin 2 | -0.0364937 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0355137 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0350371 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0348806 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0342377 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0340937 |
| TPM4 | tropomyosin 4 | -0.0324235 |
| DEK | DEK proto-oncogene | -0.0324036 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0315726 |
| MAP4 | microtubule-associated protein 4 | -0.0304405 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0301816 |
| RAI1 | retinoic acid induced 1 | -0.0291131 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0286634 |
| RBM39 | RNA binding motif protein 39 | -0.0286076 |
| SNX9 | sorting nexin 9 | -0.0275964 |
| GNAS | GNAS complex locus | -0.0274445 |
| SBF2 | SET binding factor 2 | -0.0273499 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.02732 |
| WASF2 | WAS protein family, member 2 | -0.0269661 |
| ATP13A3 | ATPase type 13A3 | -0.0264966 |
| TXNIP | thioredoxin interacting protein | -0.0261624 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0260182 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0260078 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0255337 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0255024 |
| RPL32 | ribosomal protein L32 | -0.0252923 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0251974 |
| CCNL1 | cyclin L1 | -0.0250365 |
| CTSD | cathepsin D | -0.0249796 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0249381 |
| HMGA1 | high mobility group AT-hook 1 | -0.0240773 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0238064 |
| DIAPH2 | diaphanous-related formin 2 | -0.0237917 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0235656 |
| ARF4 | ADP-ribosylation factor 4 | -0.0234858 |
| KLF6 | Kruppel-like factor 6 | -0.0233805 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0233576 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0232307 |
| MMP12 | matrix metallopeptidase 12 | -0.0230764 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0230559 |
| CLMP | CXADR-like membrane protein | -0.0230522 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0228983 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0228666 |
| IER3 | immediate early response 3 | -0.0227584 |
| CD99 | CD99 molecule | -0.0227247 |
| TMEM41B | transmembrane protein 41B | -0.0226954 |
| TKT | transketolase | -0.0222881 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0219279 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0218484 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0217593 |
| SEC24A | SEC24 family member A | -0.0217546 |
| TAPBP | TAP binding protein (tapasin) | -0.021753 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0216784 |
| RPL8 | ribosomal protein L8 | -0.0216616 |
| CD44 | CD44 molecule (Indian blood group) | -0.0215781 |
| RPS23 | ribosomal protein S23 | -0.0213952 |
| ASTN2 | astrotactin 2 | -0.0211409 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0211191 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0209031 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0208671 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0206759 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0206114 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0201272 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0201012 |
| C3 | complement component 3 | -0.0198838 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0197087 |
| PHIP | pleckstrin homology domain interacting protein | -0.0195565 |
| UBXN4 | UBX domain protein 4 | -0.0194026 |
| PCBP2 | poly(rC) binding protein 2 | -0.0191874 |
| COL1A1 | collagen, type I, alpha 1 | -0.0188816 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0186935 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0184142 |
| SETD5 | SET domain containing 5 | -0.0184131 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0177703 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0176447 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0170269 |
| TMEM263 | transmembrane protein 263 | -0.0169124 |
